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Alprostadil, a prostaglandin, has been marketed for many years as a urethral stick and an intracavernous injection for the treatment of ED. Erectile dysfunction (ED) is a very common disorder with a deep impact on quality of life on both patients and partners. Several options are available for treating ED: oral pharmacotherapy with phosphodiesterase 5 (PDE5) inhibitors currently represents the first-line option for many patients with ED. It is now available in the form of a cream (Vitaros/Virirec), a noninvasive treatment which combines an active drug (Alprostadil, a synthetic prostaglandin E1) with a skin enhancer improving its local absorption directly at the site of action.

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Alprostadil, Caverject, Edex, Vitaros,

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