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The 1983 Mental Health Act in five local authorities: a study of the practice of approved social workers. Fabry disease is a rare X-linked lysosomal storage disease characterized by the dysfunction of multiple systems, including significant gastrointestinal involvement such as diarrhea, abdominal pain, early satiety and nausea. Propagation of photic evoked responses recorded from the retina, optic chiasm, lateral geniculate body, and visual cortex of the nutritionally rehabilitated rat visual system. A clear correlation was shown between the short-term prognosis after splenectomy and the degree of hypersplenism. Ormosil based on mercaptosilsesquioxane-modified silicate (SiO2/SSQ-SH) particle was prepared by sol-gel process involving a co-condensation of the hydrolyzed 3-mercaptopropyl-trimethoxysilane (MPTMS) and tetraetoxysilane (TEOS).

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In order to document the toxic reactions related to the pathogenic mechanisms of mineral fibers, asbestos and other mineral dusts were examined for their potency to produce lipid peroxidation using the thiobarbital method for MDA measurement. Serum estrone, estradiol, estriol, progesterone, 17 alpha-hydroxyprogesterone, and testosterone were determined in the sera of 25 normal males and 25 patients with obstructive azoospermia. A unique sib pair afflicted by limb girdle muscular dystrophy type 2A (LGMD2A) is described showing a slowly progressive autosomal recessive type of muscular dystrophy with onset in the third and fourth decades.

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At equal distances and times run DBA/2J mice lacked the acute increase in precursor cell proliferation known from C57BL/6. A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB. Cluster analysis is a valuable data analysis strategy when analyzing multiple related variables. To explore the role of Dlx1as, a natural antisense transcript, in mice brain development.

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The location of the developmental site and cell dynamics of the dental lamina are parameters of a possible source for odontogenic epithelial stem cells, but the phylogenetic history is not known. The results indicate that SEI-1 was consistently overexpressed, while p16 was consistently underexpressed. Toxicological assessment of combined lead and cadmium: acute and sub-chronic toxicity study in rats.

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We conclude that PGHS monomers comprising a dimer, although identical in the resting enzyme, differ from one another during catalysis. The neuroradiological findings of children with developmental language disorder. Indium-Free Fully Transparent Electronics Deposited Entirely by Atomic Layer Deposition. We reported earlier on 1,500 hospital employees whose desire for hepatitis B vaccine was assessed.

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Stroke and TIA are recognized complications of acute herpes zoster (HZ). Estimated respiration rate was the lowest for benthivorous profundal morph, contrasting with the higher values estimated for the other morphs that inhabited shallower and warmer water. These results support a possible causal relation between the production of H(2)O(2) and actin dynamics in ABA-mediated guard cell signalling: ABA triggers H(2)O(2) generation that causes the reorganization of the actin cytoskeleton partially mediated by ARP2/3 complex, and ARP2/3 complex-mediated actin dynamics may feedback regulate H(2)O(2) production. Virtual proprioception with real-time step detection and processing. We divided mothers with PTSD into those with diagnoses present the year before delivery (active PTSD) and those only with earlier diagnoses (historical PTSD).

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Possible anatomical substrates of thought disorder in childhood complex partial seizure disorder and schizophrenia are discussed. Prior studies have shown a propensity for children with bilateral AOM to be infected with bacterial pathogens, specifically Haemophilus influenzae. Rate constants and activation parameters for the mobility of bulk and DNA-associated glycol-water solvents.

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Physiology and biophysics of hemi-gap-junctional channels expressed in Xenopus oocytes. The integrated responses of gastrin and STS showed significant correlation (P less than 0.01).

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Although HPA activation has generally been relegated to an immunosuppressive role, recent evidence suggests that stress and HPA activation can be immunoenhancing in certain situations. The role of individual, interpersonal, and organizational factors in mitigating burnout among elderly Chinese volunteers. A compilation of 17 observations of ball lightning showing the most energetic effects is presented along with estimates of their energy content. The effect of topiramate prophylaxis on medication use and medical resource use for migraine patients was studied. Nine independent isolates exhibited an 8- to 19-fold reduction in adherence and contained a transposon in the same locus.

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Insertion studies are performed to assess force administration and electrode trajectories during implantations of the Nucleus 24 Contour and Nucleus 24 Contour Advance electrodes into a synthetic model of the human Scala Tympani, using associated methods. During Easter 2012, ghost crab burrows were counted on beach sections open and closed to traffic. We also measured residential distance to major roadways and near-residence traffic density at birth and in mid-childhood. Medical records were reviewed for signalment, clinical signs, concurrent diseases, clinicopathologic findings, and results of radiography and ultrasonography. Amonafide failed to produce clinical responses in the doses and schedule employed.

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Determination of D- and L- forms of aspartic acid in Achilles tendon tissue as an indicator of age Furthermore, motor activity parameters and cardiovascular measures of the patients were related to agitation and retardation and overall, patients with lower motor activity levels demonstrated lower SBP levels. MSCs have some features (surface molecules and cytokine production, etc.) common to so-called traditional bone marrow (BM) stromal cells, which have the capacity to support hemopoiesis.

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Long-working-distance microscopic imaging in a turbid medium by use of an ultrafast optical Kerr gate. The presence of nerve fibres in the coronal odontoblast layer of teeth at various stages of root development. Soft tissue sarcomas of the trunk wall (STS-TW) are usually studied together with soft tissue sarcomas of other locations. Reticuloendothelial system Fc receptor function in systemic lupus erythematosus.

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Calcitonin gene-related peptide: enteric and cardiovascular effects in the dog. Spectral analysis of heart rate variability during isoflurane anesthesia.

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Smectic blue phases (BP(sm)) are original physical systems of thermotropic liquid crystals, displaying a double geometrical frustration: the extension of chirality in the three spatial dimensions, such as classical blue phases, and the competition between smectic order and helical twist, such as twist grain boundary (TGB) phases. An invariant asparagine residue belonging to a highly conserved domain in all protein kinases is instrumental in the protein kinase activity of the v-mil gene product. The value of Doppler velocimetry in predicting fetal distress or perinatal infection was investigated in 60 patients with premature rupture of the membranes (PROM) between 25 and 38 weeks of gestation.

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The coexistence of immunoreactivities for tyrosine hydroxylase (TH) and glutamic acid decarboxylase (GAD) and/or gamma-aminobutyric acid (GABA) was revealed in various brain regions in colchicine-injected and untreated rats, using the peroxidase-antiperoxidase method. Administration of neutralizing anti-Fas ligand antibody in vivo blocked induction of silicosis. Gene fragments were identified by sequencing plasmids of positive colonies chosen randomly. A perfusion quantification model is presented that allows the use of thinner ss inversion slabs by taking into account the offset of RF slice profiles between ss and nonselective inversion slabs.

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Spectroscopic investigation of S-Ag interaction in omega-mercaptoundecanoic acid capped silver nanoparticles. The cecal mucosa was challenged with three food antigen extracts, a buffer control and a positive control (histamine).

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This paper is a summary of systematic reviews (health technology assessment reports) of the performance and effectiveness of ambulatory blood pressure measurements for the diagnosis of hypertension. We aimed to elucidate, if children and adolescents with overweight/obesity differ from normal-weight asthmatics in lung functions parameters (FEV1, FEV1/VC, MEF50 and SRtot) and in exhaled nitric oxide (FeNO). The present paper attempts to discuss and evaluate the mechanisms of change that have been proposed as mediators of successful treatment of migraine headache. INTRASPECIFIC AND INTERSPECIFIC NUCLEAR TRANSPLANTATIONS IN TRITURUS.

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Therefore, the two-step proteolytic processing may represent a regulatory mechanism that controls cell surface expression of membrane-bound and soluble forms of CIRL. Recovery of enzyme activity did occur by 1 week if the neurotoxic effect of methylenedioxymethamphetamine was blocked by fluoxetine. The models include brain injury, neurotoxic damage, genetic diseases and inflammatory demyelination. Transient increased serum levels of this lipoprotein during acute myocardial infarction (AMI) and surgical interventions have been found. Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position.

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ER beta can enhance proliferation and invasion of breast cancer cells. Eukaryotic organisms package their genome into a number of physically distinct chromosomes, which replicate during S phase and condense during prophase of mitosis to form paired sister chromatids. Both groups had similar rates of comorbid anxiety and affective disorders.

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Previous studies focusing on single coregulators demonstrated that each coregulator is required for regulation of only a subset of all the genes regulated by a steroid hormone. Role of cytochrome b-559 in arachidonic acid activation of resting human neutrophils. The results of MRI and sonography, if either was performed, were included. Compound 1 exhibited cytotoxic activity against human cervix adenocarcinoma HeLa and murine hepatocellular carcinoma MH134 cells. We also show that transcriptional activity of reporter constructs containing human angiotensinogen gene promoter with nucleoside A at -20 is increased on cotransfection of an expression vector containing human estrogen receptor-alpha coding sequence in human hepatoma cells (HepG2) followed by estrogen treatment.

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Correlation with growth characteristics and hormone sensitivity. Enhancement of class I HLA antigen expression by cytomegalovirus: role in amplification of virus infection. Fragmentation of single biliary calculi with an electromagnetic generator Effects of halide ligands and protic additives on enantioselectivity and reactivity in rhodium-catalyzed asymmetric ring-opening reactions. Mosquito heparan sulfate and its potential role in malaria infection and transmission.

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This organochlorine mixture mimics that which contaminates the Arctic marine food chain. The Ka of cGMP for activation of monomeric mutants (PKG Ibeta (delta1-52) and PKG Ibeta L17A/I24A/L31A/I38A/L45A/I52A) is 2- to 3-fold greater than that for wild type dimeric PKG Ibeta, and there is a corresponding 2- to 3-fold increase in cGMP-dissociation rate of the high affinity cGMP-binding site (site A) of these monomers.

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Sequence-dependent correction of random coil NMR chemical shifts. The aim of this study was to select specific targets locating on the surface of epithelial ovarian cancer cells. Myeloid leukemia of Down syndrome: relation to parvovirus B19 infection and wilms tumor gene (WT1) expression.

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We describe two patients with clinical and radiological evidence of primary posttraumatic midbrain haemorrhage occurring in isolation associated with good recoveries. Large-scale preparation of rat liver mitochondria in high yield. The results revealed that the accumulation of biomass and the nutritional elements nitrogen (N), phosphorus (P), potassium (K), calcium (Ca) and manganese (Mn) in cucumber plants were significantly increased for intercropping treatments during the two growing seasons compared to monoculture. The data stress the need for a more careful selection of antibiotics in the treatment of shigellosis.

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Do patients in Dutch nursing homes have more pressure ulcers than patients in German nursing homes? Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES clones, similar to what was observed in Zfp57 mutant embryos in the previous studies. These pathology findings are in agreement with comparative studies on the metastatic behavior of different histological types of breast cancer: invasive lobular carcinoma differs from invasive ductal carcinoma by its tropism for gastrointestinal and internal genital organs. In addition, the availability of datasets with sequential images of the same tumor that are needed to characterize in vivo growth patterns for human lung cancers is limited due to treatment interventions and radiation exposure associated with multiple scans.

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Infantile spasms on weaning from breast milk containing anticonvulsants. In infants with severe congestive heart failure, earlier correction should be contemplated, although it carries a higher morbidity. Dermal delivery of lidocaine was estimated by microdialysis in 8 volunteers. Helminth co-infections in this population were associated with increased markers of the Th2 immune response, and with a host immune regulatory phenotype that may suppress allergic effector responses such as immediate hypersensitivity reactions in the skin. Factors Affecting the Pharmacokinetics, Biodistribution and Toxicity of Gold Nanoparticles in Drug Delivery.

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Here today and not gone tomorrow: the curse of chronic pain and other central sensitization syndromes. Without a multidisciplinary team, the potential to cure a select group of patients could be missed. A new amoeba, isolated from well water in Gambia, West Africa, is described and named Phreatamoeba balamuthi n. The intrinsic properties of the feed solution/suspension and the processing conditions were adjusted to ensure robustness of the process and give uniform and reproducible products, with diameters ranging from the sub-micrometer scale to a few micrometers. Evolution of barium autoionizing Stark spectra with energy and field.

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In addition, somatostatin-like immunoreactivity was seen in cells situated at the top of pituitary cleft specially in a cone-shaped extension of the intermediate lobe. Solitary bone cyst: treatment with freeze-dried cancellous bone allograft. The role of T cell immunoglobulin and mucin domain-3 in immune thrombocytopenia. Physiological principles for the design of hepatic contrast agents. Respondents were linked to the register by the Swedish personal registration number.

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We report such a case with a crossed fused ectopic pelvic kidney (L-type) with PUJO and its successful laparoscopic management. Local anesthetic lidocaine induces apoptosis in human corneal stromal cells in vitro. NSCLC cells transduced with HA-TTAA also show decreased tumorigenicity in xenograft models. The effect of somatostatin on experimental intestinal obstruction.

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Effects of diet energy level and tomato powder consumption on antioxidant status in rats. In conclusion, the lack of TLR2 was associated with an impaired host resistance to GBS infection, likely due to a diminished bacterial clearing and a consequent enhanced inflammatory response. All famotidine doses produced marked suppression of gastric secretion.

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This effect, however, was only seen when high doses of DES not included in conventional regimen were given. Oxygen desaturation during sleep in patients with chronic obstructive pulmonary disease Use of tissue oxygen tension measurements during resuscitation from hemorrhagic shock. Healthy volunteers with similar demographic characteristics served as control subjects.

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TSO induced CYP2B1/2, UGT2B1, and Mdr1b in males more than in females, suggesting that TSO could increase their expression via CAR. No cytopathogenic effect of the virus on the cells was demonstrated.

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Age-related alterations in the noradrenergic innervation of the cerebral cortex were investigated in young (3-4 months) and aged (28-29 months) Fischer-344 rats. The CSF humoral immune response is more active among African Americans (AAs) than among Caucasian Americans (CAs) with multiple sclerosis. Reference lists of identified clinical trials and personal files were reviewed.

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Etanercept is a dimeric fusion protein that binds to tumor necrosis factor and blocks inflammatory response. However, once phosphorylated the ability of IGFBP-3 to bind IGF-I is enhanced, resulting in increased association of the IGF-I with the cell membrane. LT patients receiving cyclosporine (CsA) or tacrolimus (FK) had a similar fibrosis progression rate and alphaSMA and TGFbeta(1) expression. We used murine long-term marrow cultures and a defective recombinant retrovirus vector containing the simian virus 40 large T antigen to immortalize marrow stromal cells which can support hematopoiesis in vitro for up to 5 weeks.

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While the use of intraocular lenses has not achieved widespread acceptance as a form of aphakic correction, we have obtained encouraging results in some of our patients. While this in itself does not suggest an intervention, surgical time under general anaesthesia would be a useful addition to existing risk models in plastic surgery.

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Differences are found between private and NHS patients, the latter being more physically affected. Thus, results of adenosine thallium-201 tomography are nearly always abnormal in patients with late coronary graft stenosis. Management of DBP formation can potentially be improved by reducing cyanobacteria as well as DBP precursors derived from other phytoplankton.

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EEG was recorded from 21 sites during an eyes-closed resting condition and Fourier transformed to provide estimates for total power and absolute and relative power in the delta, theta, alpha and beta bands, and for the theta/alpha and theta/beta ratios. Suggested strategies to improve healthcare access for patients with learning disabilities include: developing individualised health action plans, simplifying communication styles and providing accessible facilities and tailored resources. We conducted a cross-sectional survey in North-Central, North-West, South-East, South-South and South-West geopolitical zones of Nigeria.

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Patients with mild to moderate DSP based on nerve conduction studies were randomized into one of three treatment groups in a double-blind fashion: placebo or AS-3201 at 5 or 20 mg/day. Preliminary spectral studies of the metabolism of human brains, tumors, and a muscle of the forearm during exercise obtained with the modified system are presented. Treatment related complications included alopecia, diarrhea, weight loss, and thrombocytopenia. A day later, two clumps of rounded cells are positioned to either side of, i.e.

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Logistic regression and competing risks survival analyses were used to adjust for baseline variables and a marginal structural model analysis to adjust for confounding by evolution of disease severity before the onset of delirium. The clinico-pathological expressions of Epstein-Barr virus infection in lymphoid tissues.

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There was no evidence of an association between methylxanthine consumption and benign breast disease in the total study population. The efficacy of metallic stents in this situation is not clear, but some investigators suggest that the implantation of metallic stents in obstructed ureters may be safely and effectively performed in patients with incurable malignancies. Periodical literature about cancer survivors, health behavior models, and the IMCHB. Embryonic forebrain tissue from 17-day embryos was transplanted into the midline cerebellum of 10-day-old rat pups. Pasture infectivity with trichostrongylid larvae in the northern Guinea Savanna of Nigeria.

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However, the low quality of record keeping may imply underestimation. Interleukin-6 (IL-6) has been implicated in the development of cardiovascular disease.