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Cyclophosphamide
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Cyclophosphamide

Cyclophosphamide is the generic name of the prescription drug Cyclophosphamide, a chemotherapy drug for people with certain cancers. It’s prescribed for non-Hodgkin lymphoma, Hodgkin lymphoma, multiple myeloma, small-cell lung cancer (SCLC), leukemia, ovarian cancer, retinoblastoma, neuroblastoma, and breast cancer. Cyclophosphamide is sometimes used to treat kidney damage. Doctors may also prescribe Cyclophosphamide off-label to treat some kidney infections; systemic sclerosis or scleroderma (hardening of the organs and body tissues); and juvenile arthritis. The Food and Drug Administration (FDA) approved Cyclophosphamide as Cyclophosphamide in 1959, and Baxter International, Inc. manufactures it.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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This endogenous IFN-alpha inducer may be of pathogenic significance, since a reported occasional adverse effect of IFN-alpha therapy in patients with non-autoimmune disorders is development of anti-dsDNA antibodies and SLE. Thus, SRM-based imaging of the actin cytoskeleton and associated proteins often remains challenging and poorly reproducible.

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Further observations on immunization of sheep against Schistosoma mansoni and S. The aim of this study was to compare the efficacy of interproximal plaque removal by the hydrodynamic shear forces produced by 2 electric toothbrushes (toothbrush A, Sonicare Plus and toothbrush B, Braun Oral B) using laboratory-grown plaque biofilms in an anatomically correct in vitro brushing model. Endocytic vacuoles (receptosomes) containing influenza virus were isolated from the cytoplasm of Ehrlich ascitic carcinoma cells and characterized. Spectroscopic determination of the dynamic electrical spark temperature of nonel tube igniter Here, we provide evidence, using electron cryomicroscopy, in conjunction with light-scattering, fluorescence and kinetic analyses, that the SH3 domain facilitates the binding of the N-terminal extension of the essential light chain isoform (ELC-1) to actin.

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Streptomyces lividans contains a minimal functional signal recognition particle that is involved in protein secretion. Reliability and validity of a daily diary for premenstrual syndrome. The number of I-125 seeds or the total activity that is required to deliver the prescribed dose for the target volume can be predicted.

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Large defects, especially when associated with multiple operations and radiotherapy, are poor recipient beds for nonvascularized bone grafts. Four DDT-resistant strains were less irritated by DDT than normal colonies, the difference being significant in the two culicine resistant strains. As the result of a possible interaction of monensin and sulphachlorpyrazine, mortality was 1.7 per cent in the male and 11.2 per cent in the female birds. We report the results of LASIK in a 51-year-old woman with subsequent early-diagnosed mycobacterial keratitis and compared this case to treatments and outcomes reported in the literature. Influences of percutaneous coronary intervention on myocardial activity in myocardial infarction patients with different viable myocardium

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The information in the report is based on data assembled for the biennial report of program plan characteristics early in 1978. Participants completed a survey consisting of 12 domains that provided the basis for tailoring the AMI and shaping the campaigns. During the interview process, interviewers must be aware of and overcome these errors. This is a severe problem because it often masks broad and weak ENDOR signals.

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Quitting cigarettes completely or switching to smokeless tobacco: do US data replicate the Swedish results? The MEDLINE and CINAHL databases were searched from June 1, 2005, to July 8, 2011, to ensure overlap with the search strategies used previously. The disease was found to be caused by bilateral aplasia of the parotid and submandibular glands.

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In contrast, progressive truncation of the alphaIIb-subunit cytoplasmic domain did not reproduce these effects. TC also diminished the depressing effect of BSP on state III respiration of liver mitochondria in vitro. A continuous internal quality assurance study of the activities of an anatomical pathology department in an Australian teaching hospital was undertaken over a five year period. The activity profiles of opioid agonists and non-steroidal analgesic agents have been compared against different nociceptive stimuli in the mouse and rat. Ethical, administrative, and logistical barriers initially proved formidable and prevented the implementation of KPD programs in the United States.

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typhimurium assay or mutagenic or clastogenic in vivo in the mouse and rat micronucleus test. A histopathological diagnosis of botryomycosis tubo-ovarian abscess was made on submitted tissues. Polymorphism in glutathione-S-transferases: a risk factor in alcoholic liver cirrhosis. Limitations of these techniques and powerful applications on the horizon are also presented as we embark on an era where controlled experiments can be performed in complex mammalian models.

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Special attention is paid to the problems of expert institution readiness for work under conditions of extreme situations depending on the medical-and-tactical characteristics of damage focus. As most previous studies reporting non-significant or opposite results used females only, we also discuss some sex-related particularities that may contribute to explain unexpected results.

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Austronesian mortuary ritual in history: transformations of secondary burial (famadihana) in highland Madagascar. Renal autotransplantation as a means of revascularization in renovascular hypertension. We here present a method to analyze the response to adjuvant chemotherapy online in individual patients. Protective immunity against fungal pathogens is achieved by the integration of two distinct arms of the immune system, the innate and adaptive responses.

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Because suckling stimulation also releases epinephrine from the adrenal medulla, the present experiments tested whether catecholamines of adrenal origin may participate in the adrenergic regulation of OT release during lactation. Nonlinear dynamics of driven relativistic electron plasma waves.

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Here we discuss, with special emphasis on neural stem/precursor cells, potential mechanisms that may be involved in the action of cell-based therapies in stroke. Aspects of the bioaccumulation of heavy metals are reviewed and possible evidence of homeostasis is highlighted.

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On the mechanism of thrombogenesis during pharmacological thrombolysis. Compression arthrodesis resection of the knee (key-Charnley method) The anti-tumor activity of NPPA-PTX was also evaluated in vitro and in vivo.

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RESULTS OF THE STUDY OF TYPHOID VACCINES IN FOUR CONTROLLED FIELD TRIALS IN THE USSR. Lymphoproliferative disorders have also been linked with mast cell disease but an association with multiple myeloma has not previously been described. Noninvasive measurements of myocardial blood flow (MBF) with PET revealed an abnormal coronary vasomotor response to cold pressor test in healthy long-term smokers. Our results demonstrate that a sustainable increase of TGF-beta protein in mouse intestinal tissue can be induced after oral administration by gavage of a TGF-beta expressing DNA vector that was packed in chitosan nanoparticles. The specimen is illuminated from the side with a thin light sheet that overlaps with the focal plane of a wide-field fluorescence microscope.

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A pyridyl-monoannulated naphthalene diimide motif self-assembles into tuneable nanostructures by means of solvophobic control. The size of the blind spot (namely the vertical diameter) and the pertinent intraocular pressure are measured several times (every half an hour), in the course of which the effect of an oral dose of glycerol combined with ascorbic acid is observed. The sex-age-specific incidence rates of Grade 1, Grade 2, and Grade 3 second primary colorectal cancer (SPCRC) increased gradually with age, especially in females. These results suggest that MpiCP-1 suppresses and reverses the development of the bitterness taste that results from the pepsin hydrolysis of soybean protein by releasing mainly hydrophobic amino acids from the C-termini of the bitter components. Analyses evaluated the relationship between sleep syndromes and demographic factors, health status, and disability.

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Mapping the regulator of G protein signaling 4 (RGS4): presynaptic and postsynaptic substrates for neuroregulation in prefrontal cortex. Its prevalence, long premalignant course, and favorable response to early intervention make colorectal cancer an ideal target for screening regimens. Both the CBF lesion and the ADC lesion increased in size from first to second examination. Use of advance care planning, it is argued, can prevent moral dilemmas and improve end-of-life care.

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This study suggests a possible relation between hypercholesterolaemia and prostate cancer. Preventing after-effects of disaster trauma: the information and support centre. Combined antibiotic-immunoglobulin therapy was most effective at reducing mortality.

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Four boys aged between 7 and 9 years were referred to our clinics with the complaints of intraoral alveolar swelling or facial asymmetry on the affected area. The clinical aspects of gastrointestinal pathologies in 21 AIDS patients are examined.

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Hand radiographs from local patients and cases identified from the literature with confirmed Poland syndrome were examined for evidence of carpal bone involvement. The first was directly distributed to all Canadian residents and collected by local representatives of the SOGC Junior Member Committee in November 2002. Biodegradation of cis-1,2-dichloroethylene and vinyl chloride in anaerobic cultures enriched from landfill leachate sediment under Fe(III)-reducing conditions.

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Concentrations of 5-, 12-, 15-HETE versus myeloperoxidase activity in the periulcerous area were investigated in 40 peptic ulcer patients. Studies on serum fatty acid composition of inhabitants in a rural area, Kyoto

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Investigations of extracellular photobiochemical restoration of carbon dioxide Enlarged lymph nodes with their long axis greater than 10 mm and a short-to-long axis ratio greater than 0.5 were considered as metastatic.

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Major and Minor Duodenal Papilla Neuroendocrine Tumors in Type 1 Neurofibromatosis: Case Report. process including the dissertation carries a high cost, not only to the students who fail to complete their programs, but also to society at large due to the expenditure of scarce education resources. The activity of DPPIV/CD26 was markedly higher in PTC than in FTA, TNH, and nontumour tissues. We highlight the orbital manifestations of acute myeloid leukemia and the role of peripheral blood smear in the diagnosis of these cases.

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annual variation in absolute food availability) and variation in the timing of peak mass (i.e. Functional divergence analyses suppose that following each round of genome duplication, coevolution of ligands and their binding regions in the receptors has occurred, adjusting the endothelin signaling system to the increase of possible ligand-receptor interactions.

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The effects of 10-week physical training on both the activity and concentration of gamma-glutamyltransferase (gamma-GT) in plasma were investigated on 7 sedentary healthy male students. A Japanese multicenter study of osseointegrated implants placed in irradiated tissues: a preliminary report. On the importance of cytohistological studies in the diagnosis of vesical neoplasms

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Cross-linking of MHC class I (MHC-I) molecules on human T cells induces signal-transduction events, including activation of tyrosine kinases, tyrosine phosphorylation of phospholipase C-gamma 1, and elevation of the intracellular free calcium concentration. Gastric cancer was the cause of death in 2 men and 1 woman treated for gastric ulcer. Association of CYP3A5 genotypes with blood pressure and renal function in African families. Carcinomas caused death in five cases, four of which had initial signs of metastatic disease. In Experiment I, each box was cued by a digit shown at fixation.

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Experimental evidence of light coupling and guiding capabilities of the 1DPC is provided together with a possible application for fluorescence-based remote sensors. The inhibition of CYP3A4-mediated metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin (BFC) by CAM was assessed in Supersomes, using the fluorometric CYP3A4 inhibition assay. A novel fluorescent fatty acid, 5-methyl-BDY-3-dodecanoic acid, is a potential probe in lipid transport studies by incorporating selectively to lipid classes of BHK cells. Incorporation of a wide panel of antibody markers with clinico-cytological correlation is recommended in forming an exact diagnosis in these cases. The advantages of early surgical management are compared to the results with expectant management.

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Thus, children do not seem to be at greater risk for developing ethambutol inducted optic damage as compared to adults. Sexual practice and understandings of safe sex: assessing change among 18- to 19-year-old Australian tertiary students, 1988 to 1994.

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Structure of the pathology of the senile kidney and its diagnostic difficulties Previous concerns about feeding behaviour in cocaine exposed infants may reflect the quality of the feeding interaction rather than infant feeding problems related to prenatal exposure. Incorporation of glucose into lipid-linked saccharides in aorta and its inhibition by amphomycin. Functional carbon nanospheres have been synthesized from analytically pure glucose by a composite-molten-salt (CMS) method. This review summarizes the data from studies reflecting the validity, limitation and advantages of fecal elastase-1 in assessing pancreatic function in cystic fibrosis patients.

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Prescribing antidepressants in primary care is a more effective clinical activity than prescribing placebo. This novel approach can be of great benefit for refractory OCI cases with almost no added morbidity or complications. The design of the trial was controlled, randomized, double blind and crossover.

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This change in responsiveness of dopamine neurons following repeated ethanol administration could be related to changes in the sensitivity of kappa-receptor systems and/or an increase in dynorphin tone in the nucleus accumbens. At present, lipoprotein apheresis, combined with high-dose statin and ezetimibe therapy, is the best available means of treating patients with homozygous and statin-refractory heterozygous familial hypercholesterolaemia (FH). Considering the utility of the rodents, the interspecies similarity of the Ang II-forming pathway, and the effect of chymase in the hamsters, the present model is considered useful for studies evaluating the effect of Ang II and chymase in the canine heart with chronic pressure overload. It is quite evident the pathogenesis of psoriasis is modulated by immune-mediated mechanisms that invoke activated T cells and inflammatory cytokines, such as tumor necrosis factor-alpha.

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The level of abuse depicted in the illegal material was high, all but one consumed pornography from other fields of sexual deviation. It is probable that the reversible pneumopathy was induced by the treatment with cyclosporin A. Our results suggest that genetic diversity of epiphytic lichen demes may not necessarily be impacted by stand-level disturbances for extended time periods.

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cities were randomly assigned to one of three theory-based, structured group interventions: family-based HIV prevention, adolescent-only HIV prevention, and adolescent-only health promotion. Here we present the detailed description of sample preparation for protein and peptide MALDI imaging assays.

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Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages. An increase of adrenaline content in the hypothalamus is determined by acetaldehyde. Clinical significance of erythropoietin levels in renal carcinoma. Vascular endothelial cells maintained in the absence of fibroblast growth factor undergo structural and functional alterations that are incompatible with their in vivo differentiated properties.

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However, dynorphin-A appears to act via mu receptors in CA1, but kappa receptors in the dentate gyrus. Congenital dacryocystocele is an unusual type of nasolacrimal obstruction. Interfering substances in tissue extracts were removed by gel filtration on centrifugally-eluted mini-columns of Sephadex G-25 prior to incubation of polyglutamate substrate with tissue extract hydrolase.

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The regimes used two recombinant viral vectors, attenuated fowlpox strain FP9 and modified vaccinia virus Ankara (MVA). In this study, we conducted a critical analysis of the devices and techniques and their results.

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Post-test revealed that the plasma membrane-dominant staining pattern of SSTR 2A was significantly related to the reduction of GH by octreotide. X-ray self-emission of radiatively heated materials with different values of Z has been investigated. Oxaprotiline, a noradrenaline uptake inhibitor with an active and an inactive enantiomer.

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The patient has had a follow-up CT scan every six months, and one and a half years later remains disease free. Comparison of metatranscriptomic samples based on k-tuple frequencies. Frequency-dependent conductivity in sputtered amorphous phosphorus thin films. An antitrust analysis of physician specialty networks under changing market conditions. The results of this study support the use of indirect open reduction and internal fixation with a single extraperiosteal lateral plate, without the use of allograft struts, for the treatment of a femoral shaft fracture about a stable intramedullary implant.

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Because of an increasing demand for quality comparative effectiveness research (CER), methods guidance documents have been published, such as those from the Agency for Healthcare Research and Quality (AHRQ) and the Patient-Centered Outcomes Research Institute (PCORI). Good linear correlations between GIAO-CCSD(T) calculated (11)B NMR chemical shifts of hypercoordinate boronium 1-6b and borenium 7-9b ions and (13)C NMR chemical shifts of the corresponding isoelectronic carbonium 1-6a and carbenium 7-9a ions, respectively, were found. benthamiana plants acclimated to moderate drought stress showed reduced disease symptoms.

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Acute pernicious or sho-shin beri-beri is characterised by atazanavir pronunciation of names haemodynamic and biochemical features which include hypotension, high cardiac output, low peripheral vascular resistance, lactic acidosis and high mixed venous content. The results of this study revealed a significant difference in specific progesterone-binding capacity between proliferative and secretory endometria (P less than 0.001). The application software is a common data collection tool that can assist in building a data registry for health outcomes research. Clinical diagnostic and epidemiological assays would benefit from accurate detection of duplications and deletions commonly missed by conventional methods of polymerase chain reaction (PCR) amplification and sequencing of individual exons. NAT2 genotype is an indicator for isoniazid dosage adjusting for tuberculosis treatment.

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The dynamic kemstro classification packaging of DNA into chromatin is a fundamental step in the control of diverse nuclear processes. Hypothesis and practice: are there several types of treatment for ductal carcinoma in situ of the breast? Cold-trapping of persistent organic pollutants in the mountain soils of western Sichuan, China.

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Pooled analyses were not done because studies did fugentin augmentin antibiotic side not follow similar methods over comparable time periods. Pretreatment with BMY 7378 (5 mg/kg) significantly attenuated the reductions in glucose utilization in the hippocampus, entorhinal, piriform and cingulate cortex, induced by 8-OH-DPAT (0.25 mg/kg).

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There are some clinical and pathological characteristics in the amoxicillin clarithromycin omeprazole for h-pylori side effects patients with PBC. Treatment with anti-TNF-alpha MAb has been accepted as a successful maintenance therapy for patients with inflammatory bowel diseases (IBD). A consistent clinical and neurophysiologic pattern of either temporal or frontal lobe cortical secondary involvement was found in the patients of our series. They also discuss the role of pentobarbital-induced hypothermia. The Greyhound values were compared with 2 groups of Boxers with and without arrhythmogenic right ventricular cardiomyopathy (ARVC), and to a group of non-Boxer control dogs from a previous study.

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The effect of a putative 5-HT antagonist methysergide hymox amoxicillin rash (UML) was also examined. Structural, optical and photocatalytic properties of these nanostructures have been studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), photoluminescence (PL) and UV-vis absorption spectroscopy. Hydranencephaly in a twin gestation was demonstrated prenatally by ultrasonography and confirmed following delivery by cranial computerized axial tomography (CAT). Three kinds of gum with mean fracture stresses of 3.52 x 10(4) N/m(2) (Gum 1), 5.35 x 10(4) N/m(2) (Gum 2), and 14.0 x 10(4) N/m(2) (Gum 3) were used. Cellular and acellular cementum and the cells that form them are postulated to have different characteristics, and the relationship between these two tissues is not well understood.

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Thus, CAFs might be a therapeutic target for inhibition of gastric cancer. Sputum p38 MAPK activity was measured by cilamox syrup and honey Western blotting and sputum levels of CXCL8 and neutrophil, and lung function was measured. A fast redistribution of metal atoms occurs upon mixing the AgxAu38-x and Au38 nanoclusters in solution, as observed by mass spectrometry. Yeasts have a single major Cdk that mediates distinct cell cycle transitions via association with different cyclins. The histological observations indicated that the apatite ceramic was closely contacted with newly formed bone tissue without any rejection phenomenon up to 2 weeks.

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Collaborative care models have improved depression outcomes in primary care settings, and this study aimed to provide more information on testing such methods in specialty HCV care. It has been previously demonstrated that an embryonic raphe grafted into a serotonin-depleted hippocampus restores normal serotonin innervation of the hippocampus and behaviors associated with serotonin. Determining effects of freezing on pasta filata oxybutynin er doses and non-pasta filata mozzarella cheeses by nuclear magnetic resonance imaging. Regulation of ribosome assembly by molecular chaperones --functional analysis of nucleolar AAA-ATPase NVL2

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The HIV-1 nef protein does not have guanine nucleotide binding, GTPase, or autophosphorylating activities. Additional research is necessary to assess the optimal dose, duration, and probiotic strain or strains used specifically for facilitating enteral denai moore elsewhere review zevin nutrition in this population. Biomaterials have been modified in their properties and surface structure and loaded with growth factors to increase MSC functionalities.

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Understanding the limitations of each model available, including the nuances of tumor gene signatures, is critical for investigators exploring the phamacokinetics and efficacy of breast cancer therapies, especially in the context of gene profiling and individualized targeted therapy. tamiram 500mg nome generico Comprehensive postacute rehabilitation program in the Southern United States. The author relates natural and savage profiles of these bacterias, characterized by multiresistance due to large use of antibiotics. Statistical analysis of the data demonstrated significant linear correlations between several parameters (e.g., DO and biochemical oxygen demand, biochemical oxygen demand and fecal coliforms, biochemical oxygen demand and fecal streptococci). These observations indicate that high energy shock waves are cytotoxic to tumor cells in vitro and in vivo.