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There has been a steady increase in the number of patients with cleft lip and palate being treated at our hospital. Patients undergoing CABG living in areas with high deprivation scores are younger, have more clinical risk factors, and experience more postoperative cardiovascular complications than patients living in low deprivation score areas.

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Systematic review of antimicrobial treatments for diabetic foot ulcers. Nerves treated with glycerol did not show any severe pathological changes. A mobile robot therapist for under-supervised training with robot/computer assisted motivating systems. Of those subjects categorized as having problems with transportation, 88 per cent were women. Mechanisms of resistance to beta-lactam antibiotics in Acinetobacter calcoaceticus.

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The purpose of this study was to determine the effect of an introductory educational planning workshop on perception of teaching competencies by medical educators. However, one obvious limitation is represented by extrapolating to the ventricle events which occur at the sinus node level. These data show functional knee kinematic and kinetic differences between the two graft types that point to an earlier or better functional recovery in patients undergoing ACL reconstruction with HS graft than PT graft. The effect of spinal cord injury on sexual function and the problems that ensue are discussed. From January 2008 to June 2013, 244 patients undergoing intraoperative surgical staging after radical surgery for NSCLC were included in prospective study.

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Four new indole alkaloids were obtained from two Kopsia species, 6-oxoleuconoxine (1) from the leaf extract of K. Transient hippocampal down-regulation of Kv1.1 subunit mRNA during associative learning in rats. Our previous studies have defined reactive stroma in human prostate cancer and have developed the differential reactive stroma (DRS) xenograft model to evaluate mechanisms of how reactive stroma promotes carcinoma tumorigenesis.

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Mean followup in the treated group was 14.5 years (range 12 to 20). Hyperimmune horse anti-bothropic serum, used in serum therapy, was analyzed for its IgGT content and protective ability.

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To investigate differences between African American and White family caregivers in self-reported health, use of social support and external resources, and emotional and financial strain in the context of their care of a family member with advanced cancer. In experiment 1, rats experienced either 1 or 11 cycles of ETOH exposure and withdrawal.

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Hybrid cholecystectomies were performed in acute experiments on 50-kg pigs under general anesthesia. Minimum 2-year follow-up consisted of an ASIA motor score, an FIM, and the SF-36.

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Further studies are required for more detailed investigations of male dispersal, feeding behaviour and mating patterns in this urban setting. Renal and hepatobiliary dysfunction in chronic obstructive pulmonary disease. The forces at the yield point were lower for Optocal than for Optosil artificial test food.

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Protamine sulfate was most efficiently phosphorylated by all of the PKC subtypes tested, although this phosphorylation was independent of phosphatidylserine (PS) and diacylglycerol (DAG) or 12-O-tetradecanoylphorbol 13-acetate (TPA). Mycophenolate mofetil combined with cyclosporin A and methotrexate was used for prevention of acute graft-versus-host disease after transplantation.

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MetaboLights is the first general-purpose open-access curated repository for metabolomic studies, their raw experimental data and associated metadata, maintained by one of the major open-access data providers in molecular biology. We have synthesized and tested a cis-cleaving ribozyme designed to have thermodynamically stable stem-loop structures. The tetracycline-off (Tet-Off) system, which is a binary expression system that uses a tetracycline-controlled transactivator protein (tTA) and its tetracycline operator sequence (tetO) binding site, was developed as a method for temporally controlling gene expression. MRI contrast enhanced study of cartilage proteoglycan degradation in the rabbit knee.

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Clinical data and trauma score were obtained via medical record review. Persistence of abnormal chloride ion permeability in cystic fibrosis nasal epithelial cells in heterologous culture. The relationship between increased folate stetabolism and the increased requirement for folate in pregnancy. Mycoplasma pneumoniae infection and acute intravascular hemolysis. Primary choriocarcinoma of the lung manifesting as diffuse alveolar hemorrhage.

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In this article, some of the applications of biosensors for environmental control are described. Impact of federal legislation on dental practice and dental education.

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Small differences in bacterial loads were detected between gnotobiotic and conventionally reared A. Comparison of the development of isometric contractile properties of embryonic avian normal and dystrophic skeletal muscle. We have developed a method for scarless ligation of multipart gene segments in a truly sequence-independent fashion. This review aims to examine QoL in alcohol abuse and dependence by reviewing the instruments used to measure it and by analyzing the impact of alcohol abuse and dependence and of treatment on QoL. 33S hyperfine interactions in H2S and SO2 and revision of the sulfur nuclear magnetic shielding scale.

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The new technique was tested on 4 autogenous vein grafts (2 months after insertion) and revealed a significant decrease in intimal thickness from proximal to distal levels. Blocking the uptake of ovalbumin via the macrophage mannose receptor by using mannan led to a comparable uptake of ovalbumin by dendritic cells from all three mouse strains. Recent findings on the etiology, treatment and prophylaxis of male fertility disorders Interestingly, sequestration of endogenous VEGF in EOMA cultures resulted in a dramatic decrease in nuclear beta-catenin and a reduction in CD1 levels, whereas addition of exogenous VEGF elicited increased nuclear beta-catenin localization and increased CD1 levels in HUVEC.

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An X-linked congenital dermatological condition, Bloch-Sulzberger syndrome (incontinentia pigmenti), associated with chronic eosinophilia, was also present. Two-dimensional echocardiography and B-mode ultrasonography for the diagnosis of loculated pericardial effusion. The disease etiology, patient demographics, anatomical classification, and clinical course were investigated. Right ventricle dysplasia (RVD) is a rare clinical entity, described in young people, and a known cause of ventricular arrhythmias and sudden death. Immunoreactive cells for somatostatin and prostatic acid phosphatase were strongly detected in the carcinoid area and gradually blended to the follicular epithelium.

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Changes in membrane surface properties of hepatic peroxisomes of rats under several conditions as determined by partition in aqueous polymer two-phase systems. As in other patients, bladder stones may reflect a voiding mode that fails to ensure complete bladder emptying, but they can also be due to more specific accidents, such as a foreign body introduced into the bladder during intermittent catheterization. Pancreaticoduodenectomy (PD) is one of the most complicated procedures.

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The involvement of hypoxia in the pathogenesis of CL is in agreement with studies in mouse strains with a spontaneous rate of CL in which exposure to hypoxia has been shown to increase the rate and hyperoxia to decrease the rate. N-myc oncogene amplification and catecholamine metabolism in patients with neuroblastoma. The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network. Febrile children were serially recruited and demographic and clinical data were collected using a standardized data collection tool. The substitution analysis revealed a particular importance of residues F131, G135, I137, L138, H140 and L142 for the stability of the protein.

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By using the GST fusion protein including the full length of Grb2/Ash, we have found that c-Cbl and an unidentified 135-kD protein (pp135) are associated with Grb2/Ash. Flexible endoscopic single-incision extraperitoneal implant and fixation of peritoneal dialysis catheter: proof of concept in the porcine model. First, we evaluated the potency of individual replicon DNA or particle vaccine against TeNT, which induced strong antibody and protective responses in BALB/c mice following 2 or 3 immunizations.

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Glycoprotein-surfactant interactions: a calorimetric and spectroscopic investigation of the phytase-SDS system. Piroxicam-beta-cyclodextrin: effects on gastrointestinal blood loss and gastric mucosal appearance in healthy men. The effect of medicinal plants used in Chinese folk medicine on RANTES secretion by virus-infected human epithelial cells.

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Central representation of the anterior lateral line nerve in dwarf catfish No significant differences were found for side of body or sport. An interaction type of genetic screen reveals a role of the Rab11 gene in oskar mRNA localization in the developing Drosophila melanogaster oocyte. During sinusoidal rotation or translation, primary vestibular afferents modulate their discharge rates at the frequency of motion, effectively transmitting frequency-modulated (FM) signals.

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The results show that in keratinocytes ATRA-promoted phosphatase activity controls the proteostasis and activity of complex I. A clinical comparison of oxymorphone-acepromazine and butorphanol-acepromazine sedation in dogs.

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In this study, hydrocortisone was given to pregnant rats and the development of the fetal dopamine (DA) and norepinephrine (NE) systems in the CNS was investigated. Importantly, several of the discriminator genes were upregulated in a mutant Snail-transfected MCF7 cell known to exhibit features of EMT, thereby indicating a crucial role for EMT in the pathogenesis of MCBs. The tumor should be resected if possible, and continued low gastrin levels after operation provide evidence of a complete resection.

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The patient had many of the characteristic findings of subacute sclerosing panencephalitis, including a history of measles in early childhood, myoclonus, periodic complexes on electroencephalographic testing, persistently elevated serum and cerebrospinal fluid antimeasles immunoglobulin G (IgG) titers, and a cerebrospinal fluid oligoclonal IgG gammopathy. Pharmacological management of arrhythmias is not curative, is sometimes difficult, and may be associated with significant morbidity.

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Here we study Fe-TMPyP, a tetrapyrrole that binds to the prion protein PrP and inhibits misfolding, examining its effects on PrP folding at the single-molecule level with force spectroscopy. Early signs of compromised retinal flow and anterior ischemic optic neuropathy were demonstrated with fluorescein angiography. The results demonstrate that the phononic band diagram of such structures can be tuned mechanically. The soluble ferrochelatase contained one mole of iron in each mole of the enzyme.

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This article presents a score test for genetic linkage in nuclear families which applies to any trait having a distribution belonging to the exponential family, which includes binary and normal distributions, and distributions which are skewed or have nonnormal kurtosis. Biomimetic MRI contrast agent for imaging of inflammation in atherosclerotic plaque of ApoE-/- mice: a pilot study. Statistical analysis included Cox regression and Kaplan-Meier curves.

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