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Centriole inheritance has historically been ascribed to a template mechanism in which the parental centriole contributed to, if not directed, assembly of a single new centriole once each cell cycle. Supporting students in self-regulation: use of formative feedback and portfolios in a problem-based learning setting. The development of micronodular cirrhosis was significantly inhibited in rAAV/HO-1-transduced animals as compared to controls. In fact, clinically derived NAI-resistant variants with different NA mutations have shown different transmissibilities in ferrets (M.

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The objectives of this study were to describe the natural history of bronchiolitis obliterans syndrome (BOS) in a large consecutive series of patients from a national center in accordance with the most recent grading criteria, and to examine the prognosis with respect to onset and severity of BOS. Association of different allelic forms of group specific component with susceptibility to and clinical manifestation of human immunodeficiency virus infection.

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Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff. Moreover, the newly proposed tests can easily be extended to the case of more than one covariate. The development of efficient mucosal vaccines therefore represents a top prority in modern vaccinology.

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Mean scatterer spacing was estimated from the spectral autocorrelation, and the effective scatterer diameter and effective acoustic concentration were estimated from the Gaussian form factor. Insulin sensitivity was determined using the homeostasis model assessment. Sacral nerve root dimensions and bladder and urethral pressure responses to intradural and extradural sacral nerve root stimulation were measured to determine the optimal location and size for sacral nerve root electrodes. Two phases of MDH response to JH, dependent on ecdysteroids, could be observed. Cortical human bone samples from three tightly dated components of a single Sicilian site were chemically analyzed employing the highly sensitive technique of inductively coupled plasma emission spectroscopy.

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How these develop in an at-risk population, infants in poverty, is unknown. T1 and T2 were reported in one block of trials, and only T2 in another block (order counterbalanced across subjects).

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Blood flow rate: an important determinant of urea clearance and delivered Kt/V. A clone expressing the bifunctional antibody has been previously described by our group and was found in this investigation also to express monospecific antibodies as well as Ig forms with mismatched light and heavy chains. In the setting of RNFL thickening, despite increased light retardance in PE and ON eyes, SLP revealed that NAION eyes have less retardance, possibly associated with ischemic axonal loss. A new congenic strain, named SHR.LEW-Anxrr16 (SLA16), was developed from a cross between LEW (donor) and SHR (receptor) rats and then evaluated in several anxiety-related tests.

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The results showed that, when subjects were told to talk at different rates, response rates of the schizophrenics and controls were fairly comparable. A well-resolved ice-like (H2O)8 cluster in an organic supramolecular complex. The aim of present study was to characterize the topographical effect of thiopental on the EEG during induction of anesthesia. Time Correlation Function Modeling of Third-Order Sum Frequency Vibrational Spectroscopy of a Charged Surface/Water Interface. Dipicolinic acid (DPA) is a multi-functional agent for cosmetics, antimicrobial products, detergents, and functional polymers.

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Although much is known about the long-term outcome of stroke patients in terms of mortality and disability, there has been little research on the patient-centered outcome of health-related quality of life (HRQoL). Resting-state functional connectivity in anterior cingulate cortex in normal aging. These results confirm that VLA-4-expressing cells infiltrate the conjunctiva and that the interaction between VLA-4 and VCAM-1 is needed for the development of EC.

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For a moderate to severe injury, an impact energy threshold of 4 J, or a corresponding strain energy density of 25 kJ/m, was established. Injection of 200 microg of CRP 24 h before induction of ITP markedly decreased thrombocytopenia induced by anti-CD41.

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We have examined whether toll-like receptor (TLR)2-mediated stimulation by macrophage-activating lipopeptide-2 (MALP-2), originally purified from Mycoplasma fermentans, induces cyclooxygenase (COX)-2 and prostaglandin (PG)E(2) in human placental trophoblast cells. It is related to a syringoma and must be distinguished from a sweat gland carcinoma. We report the fine mapping of the H2-M class I gene cluster, which includes the previously reported M4-M6, the M1 family, the M10 family, and four additional class I genes. NEW VIEWPOINTS ON THE DIAGNOSIS AND THERAPY OF THE MALIGNANT GOITER

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Assuming that toxic and/or mutagenic agents may affect the ribosomal genes, satellite associations in human lymphocytes were analysed following exposure to X-rays and compared with the satellite association pattern of subjects exposed to TCDD. Only for the males in the North-west were there significant differences (P less than 0.05) in the proportions of textile workers in the three cancer sites of the tongue, mouth and pharynx.

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Twice-weekly tests of sexual behaviour showed a significant elevation of both mount latency and ejaculation latency, and suppression of mounting rate after 2-3 weeks of treatment. This injury is the most prevalent cause of sensorineural hearing loss in humans, especially from occupational exposure. No correlation between the thrombogenic factor V (G1691A), factor II (G20210A), methylenetetrahydrofolate reductase (C677T), or the plasminogen activator inhibitor (PAI)-1 promotor (4G/5G) genotypes and the risk of infection with E.

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The results showed that the expression level of PAL was increased by using Lactococcus Lactis bias codons in both Lactococcus Lactis NICE systems. Autologous greater saphenous vein is considered to be the optimal material for peripheral arterial reconstruction and coronary artery revascularization. Immediately after the foam was administered the extent of spread varied considerably, though in no instance did it extend beyond the rectosigmoid. Comparison with existing procedures is presented and experimental evidence of the accuracy improvements due to the use of a correction algorithm is shown.

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Cardiac magnetic resonance imaging in children with congenital heart disease. One probable missense mutation, A10462G (13412V), was further detected in 2 families, although cosegregation of this allele with the breast cancer phenotype was not complete. Cirrhotics who underwent orthopedic surgery had a significant increase in hepatic decompensation within 90 days of surgery compared to matched controls.

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Rational design and construction of an overproducing shikimic acid Escherichia coli by metabolic engineering Fluorometric detection of active alkaline phosphatase and gamma-glutamyl transferase in fluid dairy products from multiple species. THE D-STATE: A REVIEW AND DISCUSSION OF STUDIES ON THE PHYSIOLOGIC STATE CONCOMITANT WITH DREAMING. The intriguing association between OC use and a higher incidence of low back pain, does not enable us to conclude that there is a causal connection, but it should lead to further studies.

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Early lethality of mice null for the BMP1 gene Bmp1 or the mTLL1 gene Tll1 has impaired in vivo studies of these proteinases. The effect of dietary supplementation with an olive and soybean oils mixture.

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This suggests that immune processes are modulated by intrinsic biological rhythms. Although the mineral concentrations in water samples were generally very low some subjects received 10 per cent or more of their recommended dietary intake of Cu and Zn from this source.

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The lower limit of detection (LLOD) for 2-chlorohippuric acid and 2-chlorobenzyl-N-acetylcysteine was 1ng/ml and 0.5ng/ml in pooled urine from the pre-exposed subjects. At the in vivo length, the obstructed ureter developed less active force and less stress in response to a suprathreshold electrical stimulus than did control ureters. The functional associations of SHP2 with PDGFR beta, which transduces major growth signals in vascular SMC, identify a crucial function of SHP2 in blood vessels in consert with PDGFR beta. Focal injections of botulinum toxin A are used successfully for the treatment of hyperkinetic facial wrinkles. Kinetics and mechanism of the acid-base equilibrium of mexazolam and comparison with those of other commercial benzodiazepinooxazole drugs.

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Overall, chimpanzee samples had higher anti-SFV IgG titers than humans. Once the pain system is inhibited, other systems modulate and mediate adaptive responses that expedite the survival of the animal. The histochemical data show that the most intense accumulation of lead is found in animals kept in an environment containing 0-05 mg Pb per 1 g of the soil. Investigation of mixed-mode monolithic stationary phases for the analysis of charged amino acids and peptides by capillary electrochromatography.

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We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effects in the nematode: baicalein enhances the resistance of C. PAS measurements indicated that the bileaflet MHV activated platelets at a rate more than twice that observed with the monoleaflet MHV. Neuropeptide processing by single-step cleavage: conversion of leumorphin (dynorphin B-29) to dynorphin B.

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To define a general framework of current approaches to the discovery of disease-associated genes and the role of genetic factors in influencing disease risk through the integration of genome technology and traditional epidemiologic methods. Phosphorylation of elongation factor and its kinase expression in Rat m. These novel molecules are designed to meet specific applications. Entry of cyclic nucleotides into frog muscles in vivo and in vitro

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This case report deals with a 68-year-old man in whom a contusion resulted in a complete loss of the iris through an Elliot fistula. The deposits were subsequently curetted with the use of a transcutaneous upper and lower eyelid blepharoplasty approach and found to be entirely pretarsal.

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Interleukin-1 stimulated bone resorption and produced marked resorption when present simultaneously. Secondary brain vesicles labeling are dependent on the neuroepithelium differentiation.

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The Modification of Diet in Renal Disease Study cohort may not be representative of all patients with nondiabetic CKD because participants were more likely to reach kidney failure than death in follow-up. An overview will be given of imaging studies that looked at the role of stress (hormones) on memory. Initially this increase was caused by epithelial cells (0.25 and 1 h) and later by neutrophils (1, 2, 3, and 4 h).

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The AAA method provides a more accurate correction and makes possible, for the first time, the adequate correction of posterior sites. REACTIVITY OF THE LYMPHORETICULOENDOTHELIAL SYSTEM IN HUMAN CANCER. NSS may also be considered in cases of low-stage RCC with a normal contralateral kidney, especially in patients with local or systemic conditions that may adversely affect renal function in the future. The early diagnosis with nerve repair should yield excellent results and prevent permanent paralytic deformity. Multivariate analysis using the generalised linear model was conducted on variables associated with 72-hour ED re-attendance.

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Evidence for direct and indirect mechanisms in the potent modulatory action of interleukin-2 on the release of acetylcholine in rat hippocampal slices. This fitness defect was reversed by selective depletion of neutrophils or by inhibition of DAO in vivo with a small-molecule inhibitor. Elastase activity (ng/mg total protein) was assayed from 4-week-old cultures. Clinical trials in peanut, milk, egg, and wheat allergy provide evidence that OIT can effectively desensitize a majority of individuals to a food allergen. By this reason the patient underwent exploratory thoracotomy and the diagnosis was confirmed by the biopsy of the resected specimen: pulmonary epidermoid carcinoma.

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This large retrospective analysis supports the use of PORT for pathologic lymph node positive stage III esophageal squamous cell carcinoma. Uncertainty estimation in seismo-acoustic reflection travel time inversion. Classification of minor stroke: intra- and inter-observer reliability.

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Here we show that male GPR7-/- mice develop an adult-onset obese phenotype that progressively worsens with age and was greatly exacerbated when animals are fed a high-fat diet. Although both Stat4 and Stat6 are expressed in mammary tissue, it seems unlikely that they will have a significant function as each of these Stats is activated in response to a limited number of cytokines. Interaction of heavy metals and pyrene on their fates in soil and tall fescue (Festuca arundinacea). The plasmon frequencies agree well with existing calculations, while damping effects are underestimated by almost 1 order of magnitude. The effect of nutritional status on fatty acid synthesis in brown adipose tissue was compared with the effect of cold-exposure.

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Quantitative bone histology in the hypercalcemia of malignant disease. Assessment of pain by parents in young children following surgery. isolates, has been shown to be antigenic in humans with Lyme borreliosis, and a target for antibody-mediated disease resolution in the mouse model. Ovulation induction for in vitro fertilisation using clomiphene citrate and low-dose human menopausal gonadotrophin. To determine the effect of oropharyngeal air column area, parapharyngeal fat pad thickness, pterygoid muscle thickness, and parapharyngeal wall thickness on snoring.

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Synthetic studies toward mannopeptimycin-E: synthesis of the O-linked tyrosine 1,4-alpha,alpha-manno,manno-pyranosyl pyranoside. Thus, it can be considered as a periodontal inflammatory biomarker and deserves further consideration. Plasma Hcy levels were measured using fluorescence polarization immunoassay (Abbott Diagnostics).