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Specific 125I-iodination of cell surface lipids: plasma membrane alterations induced during humoral immune attack. Soluble oligonucleosomal complexes in synovial fluid from inflamed joints.

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IRRELATION OF KETO STEARIC ACIDS TO FATTY ACID METABOLISM IN THE RUMINANT MAMMARY GLAND. Odour sweetness increased regardless of PROP taster or sweet liker status. Patients with severe CKD show an increased risk of morbidity and mortality following gastrectomy, and their prognosis is usually poor. These findings highlight the inhibitory role of IgG4 in autoimmune disease and have important implications for the treatment of BP as well as other antibody mediated inflammatory and autoimmune diseases.

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The epidermal growth factor (EGF), its cognate receptor (EGFR) and related family members have been shown to be important in normal, as well as the malignant growth of many cell types including: glioblastomata, astrocytomas, medulloblastomata, non-small cell lung carcinoma (NSCLC) and breast cancer. All animals were autopsied at the end of the experiments, and organ probes were removed for blood flow analyses. Positron emission tomography (PET) with (18)F-fluorodeoxyglucose (FDG) has been reported to be unreliable for identifying viable myocardium in acute myocardial infarction (AMI), especially in areas with discordance in myocardial blood flow (MBF) and glucose metabolism. Motor nerve function decreases with age and can cause abnormalities in motor function. In studies examining the functional and structural consequences of resistance exercise in knee OA, stratification of analyses by varus-valgus laxity should be considered.

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mucilaginosa in toenail infection and suggest that this emerging yeast should also be considered an opportunistic primary causative agent of onychomycosis. They were addressed by feedback and corresponding amendments to protocol documentation.

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We previously proposed Emax Vd as a normalized form of Emax for heart size relatively independent of wall volume Vm, where Emax is the slope of the end-systolic pressure-volume line and Vd is its volume axis intercept. Sustained aerobic exercise did not counteract the tumor-promotional effect of increased consumption of a high-fat diet, suggesting that diet is more influential in PCa progression than exercise. Large serotonin-like immunoreactive amacrine cells in the retina of developing Xenopus laevis. The translation of viral proteins and the shut-off of host protein translation during cell infection were not inhibited in either mutant.

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An intron capture strategy used to identify and map a lysyl oxidase-like gene on chromosome 9 in the mouse. Gender Disparities in the Prevalence of Undernutrition and the Higher Risk among the Young Women of Indian Tribes. The test compound offered better action than mebendazole except against H. Substitution in this position by alkyl, alkenyl, cycloalkenyl, and alkoxy groups in many cases gives compounds whose potencies and selectivities are significantly greater than those of the parent compound. From a database of 480 children with unilateral SNHL, 148 had OAE data.

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This gives a possible experimental scheme to map a squeezed vacuum field state onto a nuclear spin state with very long storage times (hours). The identification of this nested series of somatostatins suggests that prosomatostatin processing in lamprey more closely resembles that observed for procholecystokinin than that of mammalian or other piscine prosomatostatins. Sugar derived hexacoordinated phosphates: chiral anionic auxiliaries with general asymmetric efficiency. Semantic analysis of mood adjectives in relation to positive and negative affect: evidence for combining similarly valenced mood subscales in quantitative reviews.

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For the characterization of membrane changes related to Adriamycin resistance in tumor cells, we have developed monoclonal antibodies against Adriamycin-resistant human myelogenous leukemia K562 (K562/ADM). It is shown how the expected pure phase modulation response is substantially modified in the following aspects: 1) a coupled amplitude modulation, 2) a non-linear behavior of the phase modulation, 3) some amount of unmodulated light, and 4) a reduction of the effective phase modulation as the angle of incidence increases. In addition, the adjuvant effects of bacterial toxins were much more prominent for the mucosal than the parenteral route.

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210 dogs with primary hyperparathyroidism and 200 randomly selected, age-matched control dogs that did not have primary hyperparathyroidism. Plasmid pWBG707 was isolated mostly in the open circular form and analysis with EcoRI restriction endonuclease suggests that pWBG707 is a new conjugative plasmid distinct from the other conjugative plasmids reported in S.

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An unusual case of airway rescue in the prone position with the ProSeal laryngeal mask airway. There are distinct differences in psychological features with regard to gender in patients with HFrEF.

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Forty Caucasian premenopausal women aged between 18 and 47 years, presenting with diffuse androgen-dependent alopecia, were enrolled into this study. Use of a modern micropump system allowed for continuous addition of adenosine and potassium to whole blood cardioplegia. Combined usage of sorbents and antiseptics substantially increases their curative properties. Horvitz Center for Palliative Medicine (1987-1999): development of a novel comprehensive integrated program. In spite of such a marked variability in presentation, the common findings of herniation and displacement of the mesencephalon and roof of the diencephalon allowed us to postulate that the primary defect of occipital encephalocoeles is an abnormality of the tissues overlying the mesencephalon of the developing brain.

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Astrocytic hamartomas are typically white, well-circumscribed, elevated lesions arising in single or multiple areas of the retina and epi- or peripapillary optic nerve. Simpler eucaryotes generally contain fewer pARTs: two in the fly D. We have shown that the types of mutations induced by these cancer-associated variants are different from those induced by the wild-type enzyme.

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There is considerable debate about the appropriate conceptualization of pathological gambling and its place in psychiatric nosology. In addition, relevant questions are presented for those persons who are considering accepting an interim position, including questions about the position itself and their preparation and personal goals and considerations for leaving the temporary position. The yeast complementation assay can be used to further dissect the structure-function relationship of the WRB/CAML heteromultimer in the absence of endogenous receptor proteins. In doing so, a range of information technology and other resources available to medical imaging practitioners are identified with the intention of encouraging the application of the evidence based paradigm in radiography and radiology. The MR-mRNA was demonstrated in all pyramidal cell fields (CA1-4) of the hippocampal formation and the granular neurons of the dentate gyrus.

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Rapid procedure for erythrocyte packed cell volume and sedimentation rate determinations. In contrast, sTNF-alpha stimulated the expression of TRAF1 and TRAF2, recruiting both molecules onto the cell membrane poststimulation. To identify candidate retrograde signals, we used a microarray screen to identify genes that are preferentially expressed in the synaptic region of muscle, and we analyzed one such gene, CD24, further. The evaluation of the performances of brain-computer interface (BCI) systems could be difficult as a standard procedure does not exist. The 4.2 kb and 3.2 kb mRNAs were very highly expressed in the blastula (Fig.

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Black liquor is a pulping waste generated by the kraft process that has potential for downstream bioconversion. Nasal SA carriage is frequent in patients with persistent allergic rhinitis. These techniques can provide complementing and unique information in the evaluation of myocardial blood flow, function, and viability.

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There was a significant negative correlation between the spindling time and the tissue histamine levels. Mucosal formation in the neotympanic cavity by using silicone packing in chronic otitis media with generalized destruction of the tympanic mucosa Lignin from the cell walls was isolated and characterized by thioacidolysis followed by gas chromatography and mass spectrometry. MiR-634 sensitizes nasopharyngeal carcinoma cells to paclitaxel and inhibits cell growth both in vitro and in vivo. Clinical symptoms, laparotomy and slaughter findings of a case with cystic kidneys of a young bull are described.

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It appears that the main hemodynamic effect of Ro 23-6152 in hypertensive patients is a decrease in peripheral resistance. Antigen-specific memory B cells generate anamnestic responses and high affinity antibodies upon re-exposure to pathogens.

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Aneuploidy involving chromosome 1 in failed-fertilized oocytes is unrelated to maternal age and occurs at a frequency similar to that for chromosomes 16, 18, and 21. Intranasal administration of Semax for 6 days decreased the volume of cortical infarction and improved retention and performance of conditioned passive avoidance response. The interleukin (IL)-12 family, composed of heterodimeric cytokines including IL-12 (formed by IL-12p35 and IL-12p40 subunits), IL-23 (formed by IL-23p19 and IL-12p40 subunits), IL-27 (formed by IL-27p28 and EBI3 subunits) and IL-35 (formed by IL-12p35 and EBI3 subunits), establishes a link between innate and adaptive immunity that involves different immune effector cells and cytokines to tumors. The extent of injury observed with oxmetidine was both time and concentration dependent and was similar in hepatocytes maintained in culture for 2, 24 or 48 h. All-electron self-consistent GW approximation: application to Si, MnO, and NiO.

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Since supine LBNP and upright LBPP are lacking significant differences, we conclude that both simulations are suited to simulate the cardiovascular and biomechanical conditions during activity in lunar and Martian gravities. Displacement of globe into ethmoid sinus by orbital medial wall fracture with good recovery of vision. This is in agreement with serotonin involvement in the maintenance of the hibernation state.

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A new transformation pathway, based on a Pmm2 orthorhombic intermediate state with two SiC units per cell, is found to be energetically favored over the traditional R3m mechanism. Comparison of RIFLE and AKIN criteria in the evaluation of the frequency of acute kidney injury in post-liver transplantation patients. For safer treatment of seminal vesicles (SVs), we initiated a new technique using an anchor applicator for high-dose-rate interstitial brachytherapy (HDR-ISBT) of prostate cancer. The study demonstrates that BVDV may be transmitted in cattle by artificial insemination (AI). Subsequently, the Fo complex was isolated and analyzed by sodium dodecyl sulfate-gel electrophoresis, as well as immunoblotting using antibodies raised against subunit b.

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Construction of patient-specific surface models from MR images: application to bioelectromagnetism. Studies in vitro showed that the amount of prolactin released in response to an iv injection of 50 micrograms kg-1 VIP was greater in incubating birds deprived of their nests for 24 hr than in laying hens. Primary sclerosing cholangitis (PSC) is a cholestatic disease characterized by chronic inflammatory fibrosis of the extra- and intrahepatic bile ducts. Administration of morphine (30 mg/kg i.p.) for 3 days resulted in tolerance to morphine hypothermia and also cross-tolerance to ethanol-induced hypothermia. The manuscript addresses the pathophysiology and pharmacogenetics of angioedema, reviews its classification and assesses the diagnosis and management of angioedemas exacerbated and induced by NSAIDs.

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Fifty per cent of the patients developed a second carcinoma within 5.5 years from the time of resection of their first tumor, and the time interval for the entire group ranged from one to 23 years. Effect of the surface charge on deformation dynamics in lipid membranes The methodology illustrates (a) a novel route for formation of the N-alpha-D-glucosyl-asparagine link, and (b) stereo-controlled construction of the glycan backbone alpha-Glc-(1----6)-beta-Glc-(1----6)-Glc in which the reactivity of each pentenyl glycosyl donor is controlled by an appropriate promoter.

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The following parameters are recorded: measure of brain edema, concentration of the aminergic neurotransmitters in four different brain areas, neurological status, behaviour, mortality. By means of analysis of variance we analyzed a possible association of APA with stroke severity and interactions regarding stroke severity between APA and other clinical measures. Expression in breast tumors has been documented, but the transcriptional regulation of SULT1A1 in human breast tissue is poorly understood. Some scientists have tried to prove the absolute relevance of these symptoms to psychological etiologies whereas others have insisted on biological causation. In addition to these compensation mechanisms, hyperfiltration was probably present in many cases of acute urinary tract infection with intact or unilaterally damaged kidneys.

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Our findings reveal a distinct mechanism of resistance for the H171T IN mutation to ALLINI BI-D and indicate a previously undescribed role of the His171 side chain for binding the inhibitor. The risk may even be reduced by an individual approach to the procedure.

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Unlike other dipeptidyl peptidase 4 (DPP-4) inhibitors, the excretion of linagliptin is mainly through a biliary route. In this paper, we present a full velocity difference model for a car-following theory based on the previous models in the literature. Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

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We conclude that opiate receptor agonists and antagonists do not affect vasoreactivity in the rat lung circulation and that the methyl- and propylparaben preservatives in Narcan are pulmonary vasodilators. The participation of phospholipids in the intrinsic pathway of the coagulantion process. Categorization and discrimination are the processes underlying violent aggression.

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To establish if individually tailored doses of MP can reduce myelotoxicity in ALL patients carrying mutations in the TPMT gene.To establish if variable number of tandem repeats (VNTR) genotype influences the treatment effects of MP. INACTIVATION OF ACTH BY HUMAN PLASMIN SYSTEM AND EFFECT OF PLASMIN INHIBITORS. Prelamin A is subsequently internally cleaved by the zinc metalloprotease Ste24 (Zmpste24) protease, which removes the 15 C-terminal amino acids, including the CaaX modifications, to yield mature lamin A. Our pilot study demonstrates that P-gp expression may be a reliable independent prognostic factor of survival in patients with ovarian serous carcinoma. Leukotriene E4 (LTE4) was transaminated to 5(S)-hydroxy-6(R)-S-(2-keto-3-thiopropionyl)-7,9-trans-11,14-cis- eicosatetraenoic acid (tentatively designated as LTG4) by cysteine conjugate aminotransferase I purified from rat liver supernatant in the presence of alpha-ketoglutaric acid or alpha-keto-gamma-methiolbutyric acid.

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The model suggests that the direct effect of age on cognition is substantially reduced when social, life style, physiological, and brain state variables are allowed to become intervening variables. Disease severity was assessed using two scales: the global initiative for chronic obstructive lung disease (GOLD) stage and BODE index. Here, we show that autumn coloration is stronger in species facing a high diversity of damaging specialist aphids. MIF-794CATT(5-8) microsatellite polymorphism was genotyped by polyacrylamide gel electrophoresis (PAGE).

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tritici Marchal, a discriminatory dose screen was developed to test large populations of U. The current concepts with respect to proposed etiology, epidemiology, and clinical features are discussed.

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The study attempts to estimate the demand for cigarettes in Tanzania and presents simulation results on the effect of the cigarette excise tax on smoking participation, government revenue, and related topics. One of these proteins is a 30 kDa adhesin, pI 4.9 that was described as a laminin ligand in previous studies, and it was more highly expressed in more virulent P. Stent placement with the monorail technique for treatment of mesenteric artery stenosis. Especially stathmin, polyubiquitin and heterogeneous nuclear ribonucleoprotein seem to play an important role in pre- and postnatal development. In all other patients treatment of asymptomatic gallbladder stones is unnecessary as well as any surveillance.

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Ia afferent excitation of motoneurones in the in vitro new-born rat spinal cord is selectively antagonized by kynurenate. NMR solution structural studies have served to define this conformational change and elucidate the mechanism of the linkage between calcium binding and the induced structural changes. The aim of this review is to examine the effect of PTA on quality of life (QOL) in patients with intermittent claudication. Below this CPP break point, FVa varied directly with CPP, and above the break point FVa varied inversely with CPP. Variables were grouped into: 1) general information, 2) postoperative period and 3) follow-up period.

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Two cases of invasive Haemophilus influenzae type f infection are presented: a three-week-old boy with meningitis and a 62-year-old woman with arthritis and bacteremia. Two additional populations, including a FFPE series of aged counterpart (A: 29 patients) and a group of healthy young controls (C: 21, blood provided), were also investigated to compare NGS profiles. Some of the questions are as follows: What is the best antigen form (eg, peptides, proteins, or tumor lysates)?

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Moreover, EIV have crossed the species barrier to infect dogs, pigs, and camels and therefore may also pose a threat to humans. Translocation and rotation of tRNA during template-independent RNA polymerization by tRNA nucleotidyltransferase. Amikacin given alone at a dose of 50 mg/kg, in one, two, or three divided doses, showed remarkable activity.

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The obtained data raise the problem of RNAATA application in molecular biology experiments. This study showed that condensation type polymers may show too large volumetric changes when exposed to fluids, and therefore should no longer be used in prosthetic devices. For patients who started LMV treatment in the middle stage, the mortality rate of the test group was lower.

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GPC3 inhibition of BMP2 activity is independent of attachment of the glypican on the cell surface and post-translational glycanation, and thus appears to be mediated by the core glypican protein. Role of the induced dipole moment in the collisional interference in the pure rotational spectrum of HD-He and HD-Ar. 1985)-were evaluated for their ability to detect synchronous cell assemblies from simulated spike train data.

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Nondestructive method for the characterization of ion-implanted waveguides. The technically simple performance according to the original method of Drapanas is recommended provided that anatomical variants at the surgical trunk of the vena mesenterica superior are known. These results suggest that islet neogenesis in this culture system at least partly represents the de-differentiation of islet cells into a duct-cell-like phenotype, with further re-differentiation in appropriate conditions. The mechanism by which raloxifene acts in the chemoprevention of breast cancer remains unclear.

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Section I provides a brief introduction to classical mediation outside the realm of clinical healthcare. Calculating psychoacoustic parameters of amplitude modulated narrow noise bands.

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Staged introduction of antiretroviral therapy into a family with multiple HIV-infected members. We report here the first description and comparison of the structural development of individual, functionally identified neurones in the mammalian forebrain. Eighteen semi-structured interviews were conducted with medical students who had participated in the CRT. Transcriptional and translational levels of MMP-8, -9, -13, and TIMP-1 increase during the early stages of C. Additionally, ISEcp1B provided -35 and -10 promoter sequences, contributing to the high-level expression of the bla(CTX-M-19) gene.