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Structure of hydroxyl radical-induced DNA-protein crosslinks in calf thymus nucleohistone in vitro. Anti-CD3 monoclonal antibody prolongs survival of fetal pig pancreas grafts in NOD mice.

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A variety of applications in cellular imaging, developmental biology and automated high-content screening applications are presented, which demonstrate that EosFP is a powerful tool for in vivo monitoring of cellular processes. Transcriptomic Analyses of Adipocyte Differentiation From Human Mesenchymal Stromal-Cells (MSC).

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Determination of Fe, Al, Ca in silicon metal by XRF spectrometry pneumoniae DNA present in the real-time PCR for the samples was calculated, and no significant differences in the amount of DNA between symptomatic and asymptomatic subjects were found. The aim of the SPARSE study was to evaluate the effects of the anti-tumor necrosis factor agent etanercept on NSAID intake and conventional clinical outcomes in axSpA patients. Perfusion althesin, pentazocin and an association of halothane was used in more than 500 eye operations. MDR-1 (also known as PGY1) was induced following administration of aflatoxin B1, 2-(acetylamino)fluorene (AAF), N-hydroxy-2-(acetylamino)fluorene, isosafrole, phenothiazine, and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), but not after phenobarbital or 7-hydroxy-2-(acetylamino)fluorene treatment.

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Controls were 305 African-American women without breast cancer, selected through random-digit dialing and frequency matched to cases by age and county. Health inequalities in Lithuania: education and nutrition habits. Maternal intakes of PUFAs in late pregnancy were associated with risk of later obesity differently in girls and boys. Two failures of cortisone in the preventive treatment of cicatricial stricture of the esophagus

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The charts of the 170 patients consecutively treated by the Institut Curie/Hospital Cochin/Hospital Necker Group between September 1, 2001 and August 31, 2002, were analysed. Biologically based dosimetry models that incorporate the important determinants of benzene flux, including interactions with other chemicals, will enable prediction of target tissue doses of benzene and metabolites at low exposure concentrations relevant for humans.

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Distal renal tubular acidosis developed in a patient with polyarteritis nodosa. Three Kif3 family members (Kif3A, Kif3B, and Kif3C) have been identified and characterized in mice. The detection of carious lesions on the proximal surfaces of teeth. The phytoplankton abundance influenced positively the zooplankton abundance, what indicates the prevalence of bottom-up control routes in the lateral lagoons system.

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Anti-CD40L mAb alone strongly suppressed each of these responses. The effect of psychosocial stress on muscle activity during computer work: Comparative study between desktop computer and mobile computing products. Three-dimensional structure of catalase from Micrococcus lysodeikticus at 1.5 A resolution. These paths are computed with a variant of the fast marching method and few parameters are required. The first formal World Health Organization Consultation on obesity concluded that the global epidemic is an unintended consequence of modernization, economic development, urbanization and other societal changes.

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BPP exhibits an alpha/beta-fold which is similar to the mammalian and amoeba profilins. In this case, the anaesthetic management of a child with limb-girdle muscular dystrophy is presented.

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The cardiovascular effects of oxodipine, a new dihydropyridine calcium channel blocker, were studied after i.v. Thyroxine deficient groups of all ages had reduced body weight, litter size and serum thyroxine and calcium level. The present findings also suggest that the VDR polymorphisms do not modify the effect of regular aerobic exercise on BMD. The patients were randomly assigned into two groups in a double-blind manner to perform sciatic nerve block either by the parasacral technique (Group I) or by the posterior approach (Group II). Acute correction of nocturnal hypoxemia and sleep pattern using continuous nasal positive pressure in patients with obstructive sleep apnea syndrome

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Still, results from this observational cohort suggest that mortality risk in the most vulnerable elderly population can be reduced through a program of supportive care. This study has shown that HIV associated oral lesions are prevalent in our environment and antiretroviral therapy does not have significant correlation with occurrence of these lesions in HIV infected children. Obesity is a chronic inflammatory state with resultant effects on immune, metabolic, respiratory, cardiovascular, gastrointestinal, hematologic, and renal function. An exemplary case study of a 28-year-old woman, plus episodes from the lives of seven other informants with the condition, are analyzed in order to understand, on the one hand, local social relationships between people with albinism and other individuals in family and community settings, and on the other hand, the interconnections between persons with albinism and global humanitarian actors and the broadcast media.

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Morbidity and mortality from staphylococcal toxic shock remain high, despite the availability of antibiotics to which the microorganism is sensitive. Novel inhibitor for fibroblast growth factor receptor tyrosine kinase. The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring.

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Pituitary receptors for GnRH and estradiol, and pituitary content of gonadotropins in beef cows. SAMe restores the changes in the proliferation and in the synthesis of fibronectin and proteoglycans induced by tumour necrosis factor alpha on cultured rabbit synovial cells.

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Adults who experienced childhood sexual abuse frequently find dental treatment difficult to tolerate. Measuring the role for Met endosomal signaling in tumorigenesis. Brief Behavioral Treatment for Insomnia in Persons Living with HIV. This emerging knowledge has implications for our understanding of ECM calcification beyond atherosclerosis. Relationship between central nervous system hydrogen ion regulation and amino acid metabolism in hypercapnia, II.

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Amino acid sequence of crustacean hyperglycemic hormone (CHH) from the crayfish, Orconectes limosus: emergence of a novel neuropeptide family. It has been experimentally demonstrated that intracerebral administration of the tridecapeptide alpha-MSH or even its COOH-terminal tripeptide can in fact inhibit cutaneous inflammation induced by the application of topical irritants and intradermal injection of cytokines.

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A 40-year-old man with combination of left ventricular-right atrial communication and aneurysm of the atrioventricular membranous septum is presented. PCR proved more sensitive than suckling mouse inoculation in detecting this Coxsackievirus, but a combination of both methods was required for genotypic characterization.

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The change in Rentrop score and improvement in angina status was correlated. The stratification ability of the UICC tumour node metastasis (TNM) system was compared with that of a modified system. A second finding is that the preferences for wetland conservation are heterogeneous and can be linked to livelihood characteristics.

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Conclusively, the present study clearly shows that musk ketone negatively affects reproduction and early life-stage survival in zebrafish. In validamycin A biosynthesis, as well as that of acarbose, the valienamine and validamine moieties are ultimately derived from a C(7) sugar, sedoheptulose 7-phosphate, which is cyclized to 2-epi-5-epi-valiolone by a cyclase that operates via a dehydroquinate (DHQ) synthase-like mechanism. Three purification processes have been used: electrophoresis and electro-elution, double chromatography (gel filtration and ion-exchange chromatography) and single ion-exchange chromatography. A small, but statistically significant, decrease of extracellular homovanillic acid levels was found in the mediorostral neostriatum/hyperstriatum ventrale of imprinted chicks compared to control animals, whereas changes of 5-hydroxyindoleacetic acid were not detected. Expressions of VEGF and Ki-67 in eutopic endometrium of patients with endometriosis and effect of Quyu Jiedu Recipe on VEGF expression.

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Focus groups and semistructured individual interviews were used for data collection. The alteration in these circadian urinary and haematic rhythms implies that in psoriasis not only the skin is involved: all the circadian structure seems to be perturbed and the cause of the disease should mot be searched only in the epidermis. We performed fMRI on the human parieto-occipital cortex in order to identify the neural processing regions of stereopsis. These results demonstrate that human fetal adrenal cells, in contrast to those of the adult, do not become desensitized to ACTH.(ABSTRACT TRUNCATED AT 250 WORDS) We report here the design, synthesis, and characterization of new (dioxo)Mo(VI) epoxidation catalysts based on monoanionic tridentate ligands.

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Furthermore, it was shown that monovinyl protochlorophyllide was not formed from divinyl protochlorophyllide either in barley or in cucumber etiochloroplasts. Our objectives were to assess the risk of adverse pregnancy outcome, disease flares, fertility rate, and co-morbidities in SLE women compared to healthy controls. The majority of these patients subsequently developed a disease recurrence. Family infection with certain orphan viruses was also evident from antibody development which occurred following isolation of virus in the sentinel child. The objective of the present study is to investigate the effect of HNE on tissue factor (TF) procoagulant activity expressed on cell surfaces.

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EFFECT OF PREPARATIONS INCREASING THE EXCITABILITY OF NEURAL CENTERS ON THE COURSE AND OUTCOME OF EXPERIMENTAL POLIOMYELITIS In a pioneering way, we sought to evaluate the expression of heparanase 1 (HPSE1) and heparanase 2 (HPSE2) in glandular and in stromal tissues.

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Clinical, hygienic and therapeutic remarks on the epidemiology of salmonellosis (wien type) in a neonatal medical ward R5/PTG recruits the phosphatase to the places where glycogen synthesis occurs, allowing the activation of glycogen synthase and the inactivation of glycogen phosphorylase, thus increasing glycogen synthesis and decreasing its degradation. It has been shown by investigations of polarization spectra and the dependence of the degree of fluorescence and phosphorescence polarization on emission wavelength that in non-polar solvents at 77 degrees K the molecules of Mg porphin and Mg tetraphenylporphin possess true symmetry D4h. Effect of ipriflavone on bone mass in elderly osteoporotic women. In order to avoid additional posterior stabilization in patients who undergo anterior reconstructive surgery, an anterior cervical transpedicular screw fixation, which offers higher stability is desirable.

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The efficacy, safety, and benefits of statins make them the drugs of choice. Children with asthma with at least 2 years of continuous enrollment who had medical claims for asthma diagnosis and antiasthmatic medications were selected. Reflexometry: an early prognostic test for assessing postoperative hypothyroidism

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Since this is one of the key mechanisms of signal transduction, malfunction of these potassium channels leads to a wide variety of severe diseases. Values estimated on the basis of a logistic model (EC10, EC20, and EC50) were more appropriate than NOECs and LOECs for evaluating toxicity of the test substances. The validity of the Di-EL, a parent report technique, was examined through comparisons with other measures of language development.

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Disparities between the usual patterns of clinical and anatomic involvement in giant cell arteritis underlie the potential diagnostic difficulties in this disease. Males had mean t-PA activity of 0.50 iu/ml which was significantly lower (p less than 0.01) than the females 0.64 iu/ml.

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The action of Avermectin (MK 936) on identified central neurones from Helix and its interaction with acetylcholine and gamma-aminobutyric acid (GABA) responses. Thc BRIDGE1 element from the fish Fugu rubripes is homologous to Penelope, and database searches detected additional homologous sequences among Expressed Sequence Tags from the flatworm Schistosoma mansonii and the nematode Ancylostoma caninum. Health and Safety managers were surveyed about guidelines relating to healthy work and lifestyle behaviours which impact/influence hydration. The transfected cells displayed growth inhibition and an increased rate of apoptosis. By examining the process of meaning construction, clinicians can detach from repetitive interpretations of therapy discourse that lead to conversational closure.

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The effects of early and late diagnosis on the results after brain tumor surgery. Short-Sleep mice have significantly lower thresholds to both flurothyl-induced and bicuculline-induced convulsions, as well as being more likely to suffer from paroxysms during ethanol withdrawal.

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A review of this material has permitted an estimate of egg consumption on each of 912 subjects. This effect is analogous to removing a segment of endoderm and mesoderm across the heart-forming area and results in various degrees of cardia bifida. None of the carers had organised, or planned to organise, ongoing telehealth monitoring beyond the study.

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On the recovery of spermatogenesis after cyproterone acetate therapy Infant massage is increasingly being used in the community with babies and their primary caregivers. The brainstem dorsal raphe nucleus (DRN) contains an abundant distribution of nitric oxide (NO) synthase (NOS)-containing neuronal profiles in two distinct populations: faint- and intense-immunoreactive cells in midline (ventromedial and dorsomedial) and lateral wing subregions, respectively.

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In contrast, inhibition of the constitutive NF-kappaB in HSC-2 cells by adenovirus-mediated gene transfer of a dominant-negative IkappaBalpha suppressed the IFNgamma-induced expression of the CXCL9 and CXCL10 mRNAs. Thrombotic complications after substitution with a FVII concentrate. Part of the mercury contained in the soluble phase of this organ is bound to metallothionein. Less well appreciated is the potential role of surface-active material in maintaining the patency of small airways and in transporting particles from the alveolar surface to the small airways. Pigs could be subclinically infected with PPRV by inoculation or contact with infected goats.

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This study was designed to investigate whether combination therapy with Enzastaurin and other targeted agents including Sorafenib and Sunitinib enhanced anti-tumor efficacy in renal cell carcinoma cell lines. In this study braided leads were compared with a lead incorporating a localised stainless steel electrode in 17 patients undergoing routine cardiac surgical procedures. Response properties of inferior colliculus (IC) neurons were studied in traquilized C57BL/6J mice during a period of rapid auditory system development between 12 and 17 days of age.

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Results showed that abundant phenotypic variation was presented in the population, and variation explained by genotype, environment, and genotype by environment interaction were all significant for each trait. A few factors have already been identified and two broadly different approaches to discover other virulence factors are now being used.

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Using an animal experimental infection model it could be demonstrated that with indole-positive Proteus the higher broth MIC correlated better to the observed data than the lower agar MIC when a beta-lactamase-producing strain was tested. A 56-year-old Samoan man with a documented history of hypertension, who presented with atrial fibrillation and hypotension, quickly developed renal failure with a serum urea nitrogen of 1.370 g/L and a serum creatinine of 92 mg/L. These findings may be of significance for the proposed use of the D-isomer as a class-III antiarrhythmic agent. We identified one significant QTL on chromosome 7 and 4 suggestive QTLs on chromosomes 3, 5, 10 and 13.

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All agents induced erythromycin and ethylmorphine demethylation in proportion to cytochrome P-450. The ability of these drugs to prevent KA-induced neuronal degeneration correlated with their anticonvulsant action. A subarachnoid hematoma localized in the left Sylvian fissure was identified on plain computed tomograms. The concentration of IL-8 in the basolateral medium was measured by using enzyme-linked immunosorbent assay, and the expression of IL-8 mRNA was measured by using competitive reverse transcription--polymerase chain reaction. Functional polarization of leukocytes is a requisite to accomplish immune function.

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It is suggested that sesamol conjugated metabolites are primarily eliminated from the plasma via the kidney by active tubular secretion. Although lipogenic enzyme inductions are reduced by fat feeding, this reduction decreases with aging and is particularly detectable in the case of acetyl-CoA carboxylase and fatty acid synthetase activities. Cardiovascular abnormalities and impaired exercise performance in adolescents with congenital adrenal hyperplasia. Significantly less service waste by weight (0.31 lb/meal) and volume (0.05 gal/meal) was discarded in period 3 than in period 1 (0.37 lb/meal and 0.15 gal/meal, respectively).

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The lean animals appeared to be more sensitive to the initial hyperphagic effects of PD-117302 than their obese littermates, although this initial hyperphagia was followed by a subsequent decrease in food intake so that by the end of the six-hour test period the animals treated with PD-117302 had eaten less than the saline-treated controls. In our work we diminished the influence of all other physical parameters that could influence the dissolution rate, e.g.