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Antabuse (Disulfiram)

Antabuse was the first medication approved by the U.S. Food and Drug Administration (FDA) to treat chronic alcohol dependence. In its pure state, Antabuse is a white to off-white, odorless, almost tasteless powder, which is soluble in water and alcohol. Antabuse, an alcohol-aversive or alcohol-sensitizing agent, causes an acutely toxic physical reaction when mixed with alcohol. Continuing research and clinical findings have clarified Antabuse's mode of action and established its safe and effective use in the treatment of alcohol use disorders (AUDs) in some patient groups.

Other names for this medication:
Disulfiram, Antabuse, Anticol, Aversan, Esperal, Etabus, Tenutex,

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This may be mediated by a change in the expression of the two isoforms of the PR, with an increase in the PRA:PRB ratio, and this is accompanied by an increase in the expression of the estrogen receptor. In addition, osteoclast activity is critically regulated by osteoblasts that can respond to bacterial pathogens and foster both inflammation and osteoclastogenesis. The physiological effects of beta-adrenergic receptor stimulant on the rabbit lacrimal gland

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The rest required either additional medication or trabeculectomy. Adjuvant concurrent chemoirradiation in locally advanced rectal cancer confers a significant improvement in local control and overall survival compared with either modality alone. Therefore, the multiple unit drug delivery system can be described by adding the velocity-time equations of different pellets to calculate the theoretical equations. It was time-consuming and it required rigorous and simultaneous data collection and analysis, including reflective writing. In addition, the clearance of retroviruses by the entire manufacturing process of an immunoglobulin, human plasminogen, a murine monoclonal antibody and a recombinant human protein were studied.

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The interaction between two non-depolarizing neuromuscular blocking agents, pancuronium bromide and vecuronium bromide, has been studied at standardized levels of neuromuscular blockade and alternating the sequence of their administration, in 40 surgical patients. A newly identified AMSH-family protein is specifically expressed in haploid stages of testicular germ cells. Then, a continuous hydrogen production experiment was conducted by using bean curd manufacturing waste as an actual organic waste at pH 5.5 at 35 degrees C.

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Triply differential cross section for ionization in ion-atom collisions. The goal of this paper is to investigate dose distributions for three small animal radiation treatment modalities. In asynchronous broods, A-chicks had higher baseline corticosterone than their siblings, contrary to our expectations.

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tularensis) LVS, to elicit immunity in mice against subsequent systemic and aerosol challenge with highly virulent strains of the pathogen. SPECIAL MEDICAL COMMITTEE INVESTIGATING MATERNAL MORTALITY IN NEW SOUTH WALES: REPORT ON DEATHS ATTRIBUTED TO RENAL DISEASES AND PREGNANCY, 1957-1960. The Anger camera and the pertechnetate ion in the routine evaluation of thyroid uptake and imaging. The distribution of somatostatin immunoreactive forms in three tissues of the anglerfish (Lophius piscatorius L.) was analyzed by a combination of gel permeation, High Pressure Liquid Chromatography and amino acid analysis.

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Based on landscape classification of remote sensing data and spatial expression of environmental factors, the abiotic ranges of forest landscape distribution in Changbai Mountain Natural Reserve were determined by using GIS. Forty-one patients younger than 2 years of age with no experience of egg intake due to concerns regarding allergies or a non-specific clinical response to eggs were enrolled. Newer design features provide for smaller delivery size (16 fr), facilitate accurate placement, and provide the option when the device is partially deployed to recapture and reposition the device if necessary.

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Results indicated that vascular injuries are crucially responsible for perioperative and postoperative crisis. Gemcitabine plus nab-paclitaxel regimen was demonstrated to increase survival compared with gemcitabine monotherapy and is therefore indicated as first-line therapy in patients with metastatic PDAC and performance status Eastern Cooperative Oncology Group (ECOG) 0-2. New applications of FTIR micro-spectroscopy in the field of forensic science Stem cells first enter the thymus around the 11th to 12th days of gestation in BALB/c mouse embryos. The only antibiotics judged to be so unpalatable as to potentially jeopardize compliance were dicloxacillin, oxacillin, erythromycin/sulfisoxazole, and cefpodoxime.

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He made outstanding contributions to the study of leprosy, the identification and isolation of the active principle in the lepromin reagent, the use of lepromin test for identifying persons susceptible to leprosy, the use of an antileprosy drug as a means of chemoprophylaxis, the nurturing of the Indian Journal of Leprosy and developing it as one of the foremost leprosy journals, are a few of his major contributions. Haemocytes are the invertebrate blood cells and thus have been shown to be involved in defence mechanisms.

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The personality of pursuit: personality attributions of unwanted pursuers and stalkers. The Maudsley Hospital: design and strategic direction, 1923-1939.

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Major differences between lung, skin and liver in the microsomal metabolism of homologous series of resorufin and coumarin ethers. Effects of fasting, feeding, and bethanechol chloride on pancreatic microsomal protein synthesis in vitro. Vitamin D-induced calcium-binding protein: comparative aspects in kidney and intestine.

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Mouse horizontal cells are coupled by gap junctions composed of connexin57. Wyeth-14,643 (WY) belongs to a diverse class of compounds which have been shown to produce hepatic peroxisome proliferation and hepatocellular carcinoma in rodents. Healthcare costs associated with antiretroviral adherence among medicaid patients. In the period 1969-1981 24 patients between the ages of 27 and 74 were operated on. Intradermal melanocytic nevus with lymphatic nevus cell embolus: A case report.

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The role of triglyceride-rich lipoprotein families in the progression of atherosclerotic lesions as determined by sequential coronary angiography from a controlled clinical trial. Extended use of the internal mammary artery graft: important anatomic and physiologic considerations. By this effect no cost-containment, which is one of the legislative purposes for Integrated Health Care, will be achievable. Immunocytochemical examination of wild-type neurons in cell culture showed RPTPsigma protein in the growth cone. Acetaldehyde accumulation in excised wheat roots induced by plant growth substances.

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Subsequently the retrograde labeling of the substantia nigra neurons was studied after combined injections of the two fluorescent retrograde tracers in two of the above structures, in different combinations. The filament, straight and tilted with respect to its rotation axis for small driving torques, undergoes at a critical torque a strongly discontinuous shape bifurcation to a helical state. Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast.

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