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The metabolism of xenobiotics was monitored by analyzing aryl hydrocarbon hydroxylase, epoxide hydrase and ethoxycoumarin O-deethylase activities as well as the activity of UDPglucuronosyltransferase using both p-nitrophenol and 4-methylumbelliferone as aglycones. At each fixed train duration, maximal bradycardia was achieved with pulse frequencies between 80--120 Hz and remained maximal up to 160 Hz. A follow-up program for women with previous gestational diabetes mellitus. In contrast, control antibodies recognizing the choline-binding proteins (CBPs) PspA and PspC showed high reactivities. The key exposures were baseline energy intake, physical activity at work, alcohol consumption and smoking status.

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Their structures were established by extensive two dimensional (2D) NMR techniques and chemical evidence. While the neutrophil plays an essential role in defending against bacterial infection, it can also cause significant injury to the host tissue. Stimulation of lens epithelial cells with IGF-1 for 10 minutes to 24 hours resulted in the sustained activation of both Akt and p70 S6K.

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Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. Comparison of the intravenous and intraperitoneal routes of administration of tritiated thymidine in studies of cell production in the gastrointestinal tract of the rat.

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Our studies revealed that deletion of Lcn2 in Hfe-knockout mice does not influence hepatic iron accumulation in Hfe(-/-) mice, or their response to iron loading, as the phenotype of HfeLcn2(-/-) mice remained indistinguishable from that of Hfe(-/-) mice. Nitrogen-fixing associations of fungi and bacteria have been isolated from the soil and flooring of coniferous forests. Secondary glaucoma was defined as glaucomatous optic nerve damage and/or visual field abnormalities suggestive of glaucoma with ocular disorders that contribute to a secondary elevation in IOP. Previous studies have shown that neural oscillations in the 8- to 12-Hz range influence sensory perception. a total of 113 patients, with 127 symptomatic and asymptomatic plaques, were studied.

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Maternal anthropometric risk factors for caesarean delivery before or after onset of labour. In addition, the greater the quantity of human milk fed, the lower the morbidity. The disease was thought to be caused by a congenital cholestatic syndrome associated with intermittent oedema in childhood, resembling the rare Aagenaes syndrome. This case demonstrates that sentinel node biopsy can be performed safely in children.

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A reappraisal of the major advances in the diagnostic pathology of adrenal cortical lesions and tumors in the last 25 years is presented, with special reference to the definition of malignancy in primary adrenal cancer and its variants. This unexpected association, if confirmed in future studies, could influence risk-related treatment strategies for cardiovascular disease.

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Albino rats, both males and females were adrenalectomized (Adx.), either on the eleventh or the twenty fifth day after birth and the body weights recorded daily until the sixtieth day when all the animals were sacrificed. Some contributions of electron microscopy to knowledge of human platelets. The PAHs extraction enhancement factor compared to water was about 200. When dividing cells are subjected to abrupt nutrient shift-up by transfer from a chemostat culture to medium with excess food, or shift-down from a well-fed culture to exhausted medium.

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TFE3 is a bHLH-ZIP-type transcription factor that regulates the mammalian Golgi stress response. Diastereoselective synthesis of arylglycine derivatives by cationic palladium(II)-catalyzed addition of arylboronic acids to N-tert-butanesulfinyl imino esters. Effect of transient BK viremia and viruria on long-term renal allograft survival and function. The author discusses possible reasons for the lack of a facilitatory effect of regularity.

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The Shedler-Westen Assessment Procedure (SWAP): making personality diagnosis clinically meaningful. The athletes are evaluated by clinical protocol which includes Holter monitoring ergometric test, echocardiography study, thyroid check and transesophageal electrophysiologic study at rest and during exercise. Subcutaneous nodules with malignant presentation, but caused by infection Fluorescent microscopy and Western blot analyses revealed specific binding of the anti-flagella pentabodies to the C.

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None of the laboratory animals, including the marmoset, provided an approximation of the enzyme profile associated with human faecal flora. The anterior cortex is relatively strong in tension, the posterior in compression. Separable sustained and selective attention factors are apparent in 5-year-old children.

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Cotton bracts are adapted to a microenvironment of concentrated CO2 produced by rapid fruit respiration. Systolic dysfunction is often associated to diastolic alteration, pseudonormal and restrictive filling pattern are related with poor prognosis. There was however an association with increased cataracts and pneumonia hospitalisations.

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Perceptions of health-related quality of life of men and women living with coeliac disease. It is concluded that the increase in blood glucose following the administration of oxytocin is secondary to the release of glucagon and that oxytocin exerts a direct stimulatory effect on glucagon and possibly insulin secretion. Management of villous papillomas of the lower portions of the sigmoid and the rectum.

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Difference in the perception of the horizon during true and simulated tilt in the absence of semicircular canal cues. The further course of the disease was found to be an inflammatory reaction. The prevalence of gallstones is significantly higher in patients with liver cirrhosis, and the related risk factors are diabetes, hypertriglyceridemia and severity of liver cirrhosis.

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In addition, the computational expense to determine the electron density and its corresponding energy for a large scale structure, such as a carbon nanotube, is shown to be much more efficient compared to the conventional Hartree-Fock method using the 6-31G Pople basis set. Retrospective clinical magnetic resonance imaging study and prospective magnetic resonance imaging volunteer study of the appearance of the ligamentum flavum. The specific activity of pyroglutamyl peptidase II in Y79 retinoblastoma cells was greater than the highest activity found in other cell lines by approximately one order of magnitude. The sample comprises over 3000 year 9 pupils (aged 13-14 years) in 45 mixed secondary comprehensive schools in England.

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Percutaneous left brachial catheterization using 5-French preformed (Judkins) catheters. Impaired amino acid metabolism and its management in chronic renal failure Ovariectomy evoked an increase in total lipid and phospholipid concentration, has no effect on glycerides and lowered total cholesterol concentration in rat adrenals, while estradiol replacement diminished concentration of all classes of lipids studied. Follow-up status of each patient domiciled outside the treatment centre was analysed from a postal questionnaire.

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On the basis of the results of this study, dental surgeons should consider cementing fixed prosthesis with resin cements for patients who are exposed to marked variations in environmental pressure, such as divers and submariners during escape drills. An association between elevated serum MBL and diabetic nephropathy was also observed. Autoimmune strain (NZB/kl) mice, in which autoimmune disease can be spontaneously induced, were used in this study.

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Recent legislation affecting diathermy, short-wave and similar apparatuses Normal transcription and postranslational processing of the preprotachykinin (PPT)-I gene and regulated release of substance P and neurokinin A by the rat pancreatic endocrine cell-line, RINm5F, has been demonstrated, using radioimmunoassays (RIAs), reversed-phase (rp)HPLC and Northern blot analysis. Two hundred patients who had undergone primary, unilateral TKA for knee osteoarthritis were randomized to 1 of 2 interventions 4 weeks after surgery, and 41 patients eligible for enrollment who did not participate in the intervention were tested 12 months after surgery (standard of care group). CD40 is one of the key molecules involved in the survival, growth and differentiation of B lymphocytes. Nimesulide-L-lysine-beta- or gamma-cyclodextrin complexes were prepared by spray-drying.

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The fragile nature of bilayer membranes is the major difficulty for the application of the artificial bilayer technique to the development of biosensors. Affymetrix GeneChip microarrays are typically processed using model-based algorithms that require all of the data in order to adequately estimate the model.

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The ServOMap system we implemented is able to deal with hundreds of thousands entities with an efficient computation time. Chemesthetic responses to airborne mineral dusts: boric acid compared to alkaline materials. The two-by-two table method, receiver operating characteristic curve, and Bland-Altman analyses were used to characterize the ability of CE-MRA to discriminate carotid and arch anatomy, suitability for CAS, and degree of carotid stenosis.

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Trigeminal thresholds (i.e., pungency, localization and eye irritation) could be obtained on all repetitions only for some terpenes using that same criterion. Redox potentiometry coupled with optical spectroscopy allowed the midpoint potential of the redox center to be determined for the CbiXL from both B. However, VILIP expression increased the beta-adrenergic receptor-stimulated cyclic AMP (cAMP) level in these cells severalfold.

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The study reviewed 1521 panoramic radiographs of Saudi and non-Saudi subjects who attended RCsDP clinic from November 2009 to November 2010. The likely structure of equine corticotropin releasing factor is: Ser-Glu-Glu-Pro-Pro- Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg- Ala-Glu - Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2. Publishing and its associated factors in teachers of scientific research in schools of medicine in Peru

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Population growth, life-cycle saving, and international differences in steady-state optimal saving rates. Therefore, we hypothesise that the unrealised benefit of cervical cerclage is at least in part due to the type of suture material used. Three patients obtained a significant improvement of esophageal symptoms after the first injection.

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This novel Ahr action on cell plasticity points to a role in cancer progression. Patients with severe renal dysfunction eliminate argatroban at a rate similar to that in healthy volunteers, while those with hepatic disease have a marked decrease in argatroban elimination.

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The remainder of the program uses the counts per minute, SCR or ESR, and post-dialysis volume of paired plasma and buffer samples generated from the dialysis procedure to compute the extent of binding after correction for background radiation, counting efficiency, and intradialytic shifts of fluid between plasma and buffer compartments during dialysis. Supratentorial lobar pilocytic astrocytomas: report of 45 operated cases, including 9 recurrences.

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The development of this questionnaire is an important step in providing a reliable and validated instrument for use to guide appropriate investigations, referrals, or interventions in clinical and research settings. The ratio of maximal to partial expiratory flow rates (VM/VP) was significantly correlated with methacholine airway responsiveness, even after adjustment for age and baseline FEV1. Idiopathic headaches (migraine, cluster headache) are very often accompanied by alimentary canal disturbances. Specific somatostatin-binding to cytosol of bovine gallbladder mucosa. Reverse genetics was used to identify mutations in a gene, No Transmitting Tract (NTT), encoding a C2H2/C2HC zinc finger transcription factor specifically expressed in the transmitting tract.

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Subcutaneous right leg metastasis from rectal adenocarcinoma without visceral involvement. The work input is fully utilized to decrease the entropy of the outflowing streams compared to that of the inflow. Our results show strain variability in the genome-encoded repertoire of iron-transporting systems and differences in efficacy to use complex iron sources for growth and biofilm formation. At 2 wks after injection, a necrotic cleft was clearly visible, along with collapse of the trilaminar zones.

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Gi affects the agonist-binding properties of beta-adrenoceptors in the presence of Gs. On the other hand, a hyperglycemic factor from the CNS inhibits glycogen synthesis and stimulates glycogen breakdown in these cells.

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Principles and applications of Raman spectroscopy in pharmaceutical drug discovery and development. Attenuation of hypoactivity by TRH and analogues was not due to increased dopaminergic function because apomorphine (5 mg/kg) was ineffective. Estrogen receptor positive or estrogen receptor negative primary carcinomas did not show any predilection for spread to any particular site. To investigate a possible association between transporter gene polymorphism and gallstone formation, we examined five common polymorphisms in the ABCG5 (Q604E) and ABCG8 (D19H, Y54C, T400K, A632V) genes in patients with gallstone disease (GS).

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Reducing the overlap problem in the proton NMR spectra of oligosaccharides by application of pseudo-four-dimensional homonuclear HOHAHA-HOHAHA-COSY. administration of a new standardized sonographic contrast agent. Variations in serum copper and ceruloplasmin levels in advanced gastrointestinal cancer treated with polychemotherapy. In situ ATR FTIR studies of SO4 adsorption on goethite in the presence of copper ions.

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Nerve growth factor promotes corneal epithelial migration by enhancing expression of matrix metalloprotease-9. Current studies are defining the essential relationship between carboplatin AUC and the likelihood of achieving a therapeutic response in various tumor types. Although these numbers are too small for us to arrive at conclusions, we think it is possible that there are some mechanisms connecting GH replacement therapy and recurrence of certain brain tumors.

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The amplitude of intra-annual variability generally increased with latitude. Impaired interleukin 1 and interleukin 2 production following in vitro abortive infection of murine spleen mononuclear cells by Semliki Forest virus. Evaluation of microvascularization in focal salivary gland lesions by contrast-enhanced ultrasonography (CEUS) and Color Doppler sonography. Histochemical in situ evaluation ofLDH and reactive oxygen species (ROS) were also performed.

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In comparison to the sexual attitudes of an untreated control group those of the sample group were found to be more permissive after than before the program. The lipid-derived inflammatory mediators leukotrienes (LTs) are produced during vascular injury. Nursing staff stress from challenging behaviour of residents with dementia: a concept analysis. Cotransfection of BAD with constitutively active Akt cDNA strongly inhibited this change. Adaptation to larval crowding in Drosophila ananassae and Drosophila nasuta nasuta: increased larval competitive ability without increased larval feeding rate.

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What is known, however, is that different areas in the brainstem transmit information to the thalamus and cortex necessary for sleep-wake regulation. Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease. We have adapted it to the usual case of ignoring the distribution of the whole set of observed variables, but assuming that some knowledge about the marginal distributions is available. Alterations in nuclear phosphoproteins of a temperature-sensitive Chinese hamster cell line exposed to non-permissive conditions. Due to the presence of these BKV sequences, pRP-c replicates in human cells allowing amplification of inserted cDNAs.

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Congenital thoracic ectopic kidney is a very rare developmental anomaly and the rarest form of all ectopic kidneys. Based on this unexpected differential sub-cellular localization, 15 other GST family members were expressed as GFP fusions in tobacco. They produce sufficient excitatory drive within the spinal networks to generate coordinated locomotor activity.

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Prospective memory performance is sensitive to regular and even moderate ecstasy use. Seven patients with polypoid mucoceles of the ethmoid sinuses were examined by computed tomography (CT).