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Clarazole (Ketoconazole)

Clarazole is an imidazole antifungal agent. Clarazole has oral tablet, cream and dandruff shampoo formulations. The oral formulation is available in USA since 1981. Clarazole is the only member of the imidazole class that is currently used for treatment of systemic infections. Clarazole is a highly lipophilic compound. This property leads to high concentrations of Clarazole in fatty tissues and purulent exudates. Expectedly, the distribution of Clarazole into cerebrospinal fluid is poor even in the presence of inflammation. Its oral absorption and solubility is optimal at acidic gastric pH. While Clarazole was more widely used before the development of newer, less toxic, and more effective triazole compounds, fluconazole and itraconazole, its use has now been limited. It now appears as an alternative drug for specific indications.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

Similar Products:
Phexin, Suftrex, Barazan, Vaclo, Gabator, Gastrolan, Klindacin, Antivir, Claromycin, Aroxin, Eupantol, Adiva, Duomox, Pansec, Zepoxin, Cliz, Duricef, Venlift, Ulceral, Prednisolone, Ofloxacin, Belivon, Claron, Azel, Biogel, Amodex, Clavucid, Zefu, Simarc, Clavubactin, Trichazole, Nemasole, Llanol, Duracan, Lancid, Buscogast, Tamsol, Unixime,

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The principles of paternity exclusion and current systems of paternity testing are reviewed. To examine whether Chinese studies of child sexual abuse (CSA) in the general population show lower prevalence rates than other international studies, and whether certain features of these studies may help to account for variation in estimates.

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We report the cases of 2 children with occult, unicentric Castleman disease whose primary presenting feature was a chronic, unexplained, iron-refractory, microcytic anemia. We did not use any date or language restrictions in the electronic searches for trials.

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Muscle disease caused by mutations in the skeletal muscle alpha-actin gene (ACTA1). Since 1997, autologous stem cell transplantation (ASCT) had been applied to more than 40 children with polyarticular or systemic juvenile idiopathic arthritis (JIA). Ab initio calculations of YAg, YCu and NiAl crystal defect energies support the observed deformation modes of these intermetallics. Virus particles indistinguishable from purified virions were detected by electron microscopy in phloem exudate.

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Glucose and maltodextrin in enteral diets have different effects on jejunal absorption of nutrients, sodium and water and on flow rate in mini pigs. jejuni behaved identically to cholera toxin on non-denaturing polyacrylamide gel electrophoresis. Peptidyl-arginine deiminase 4 (PAD4) has been shown to convert arginine residues into the non-genetically encoded citrulline residue. The effects of inhibitory control training on alcohol consumption, implicit alcohol-related cognitions and brain electrical activity.

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The failure of testosterone lotion to aggravate acne vulgaris in teen-age males. These processes are thought to realize a non-hormonal initial event to a benign or malignant disease. It was concluded that the FMTMT, as compared to the SSTMT, required finer and more rapid laryngeal control to coordinate respiratory driving pressures and glottal resistance, and hence was more susceptible to impairment of the laryngeal mucosal reflexogenic system. In this chapter, we discuss the advantages and limitations of activation tag screening and describe a protocol for identifying activation tag lines with enhanced cell expansion, using dark-grown Arabidopsis thaliana seedlings as an experimental system.

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First announcement of the Fanconi anemia International Registry. Psychoactive pharmaceuticals at environmental concentrations induce in vitro gene expression associated with neurological disorders.

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As this study is a survey involving a large male sample, homogeneous with reference to age, race and country of origin (southern Italy), the frequency of XLI could be estimated at about 1.98 per 10,000 males. Data were available for 118 patients with first-episode schizophrenia in a longitudinal treatment study.

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No heme release was observed for deoxy, oxy, carbonyl, or azide derivatives of the Aplysia myoglobin, or when the distal HisE7 of the apohemoprotein is replaced by leucine or valine. They face forward and slightly downward and may have significant overlap in visual fields. We selected 15 studies: 9 assessed the rate of DE after CNB and 6 the impact of CNB on outcome endpoints. In fact gastric microcirculation supplies both nutrients and bicarbonate to the gastric mucosa and provides removal of back-diffused hydrogen ions. The records of all patients diagnosed with perianal abscess from January 2011 to December 2011 were reviewed.

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The next decade should prove to be an exciting one for those involved in the molecular analysis and clinical management of human muscular dystrophies. An unusual case is presented of three dental developmental anomalies, a hypomaturation-hypoplastic with taurodontism form of amelogenesis imperfecta, hypodontia of the premolars and an odontoma, occurring in an otherwise normal boy.

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The study evaluated how the detection efficiency varies with the length and width of Gabor wavelets of depth ripple in random element patterns. Twenty-two patients had previous microsurgical resection and all patients experienced various cranial neuropathies. Consequently, there is potential for significant pharmacokinetic (PK) interactions between these two classes of medications.

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The fibrinogen RIBS-I epitope (gamma373-385) appears proximate to the gamma408-411 adhesive domain but is not involved in interaction between receptor-bound or surface-adsorbed fibrinogen and platelet GPIIbIIIa. If a three dimensional (3D) ultrasound dataset is acquired without manual intervention of the technician, repeatability and patient follow-up could be improved. Granulocytes from healthy rabbits and from rabbits with P multocida infections were equally competent. Despite recent data that suggest that the overall performance of drug-eluting stents (DES) is superior to that of bare-metal stents, the long-term safety and efficacy of DES remain controversial. Clinical and technical measures to improve the fit of whole-cast fixed dentures to the denture bed

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The mechanistic basis of these abnormalities, as well as their potential relationship to dentate granule cell neurogenesis, is unknown. It describes procedures to use and techniques for interpreting test results, and finally includes a study of normal reference values. This biotechnology is more likely to develop into medicine for preventing a genetic disease if corrective genome editing is integrated into assisted reproductive technology, represented by in vitro fertilization. Genome wide association studies for complex diseases are typically followed by more focused characterization of the identified genetic region. A modified version of the Composite International Diagnostic Interview was administered to a probability sample of 8098 community respondents.

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In contrast, all 4 HEMA/EMA biopsies contained collections of pDCs in lymphocytic infiltrates close to filler particles and adjacent sarcoidal granulomas. From the possible methods of general anaesthesias, in practice injection anaesthesia has been generally accepted for several reasons.

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By GABA-immunocytochemistry it was demonstrated that not only Golgi axons but also the Golgi somata and presynaptic dendrites contain GABA, suggesting that this inhibitory transmitter is an operating factor in many of the newly formed synapses. Speed/time of cognitive performance is commonly decreased early after on-pump surgery either. Similarly, eNOS nitration induced by NO exposure was reduced by p21ras C118S transient transfection, and increased by the overexpression of wild-type p21ras. We offer a variety of comparisons between the QWB and Medical Outcomes Study Short Form 36 (SF-36).

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The most frequently used methods for detecting antibodies are the indirect immunofluorescence test and the enzymatic immunoassay (ELISA). The functional recovery of 47 right-brain-damaged stroke patients was studied over a 2-year period. Quality standards for performing stent-graft procedures as well as for pre- and postoperative patient management are lacking, so far. Neither of the metabolites, MBuP, MBzP or PA, supported growth of the test organism, while in resting cell transformation, the monoesters were hydrolyzed to PA to a very minor extent, which was found to be a dead-end product in the degradation process. Thawed vitreous samples were sonicated with HPLC grade water and the aqueous layer was extracted three times with chloroform and then three times with n-butanol.

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Several studies investigated the association of histologic scores of donor kidney biopsies obtained before engraftment with posttransplant outcomes. Long-term local control and cosmetic outcome are excellent and similar to patients boosted with either electrons or photons. In addition, a vector containing HPV16E6/E7 was transiently transfected into oral cancer cell lines. Clinical evaluation of endoscopic trimodal imaging for the detection and differentiation of colonic polyps.

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The highly diversiform and well developed lymphoid tissues of sturgeons may serve as basis of efficient immune mechanisms. In some substances, therapy can be determined by control of plasma concentration levels, in other drugs dosage is possible exclusively according to clinical effects.

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Inhibition of apoptotic pathways failed to inhibit BCG-induced cell death in UC cells. During expansion, fluid reabsorption by the nephron segments did not differ appreciably among the three groups. The tilt of the limb segments was calculated by combining the signals of the accelerometer and the rate gyroscope. Desired vancomycin trough serum concentration for treating invasive methicillin-resistant Staphylococcal infections. Genome typing of adenovirus strains isolated from conjunctivitis in Japan, Australia, and the Philippines.

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Labeled tectospinal and crossed tectoreticular neurons were far outnumbered by neurons with ipsilateral reticular projections. Conditioned medium from coculture experiments indicated that the release of LCN2 from macrophages induced tube formation and proliferation in cultures of primary human lymphatic endothelial cells in a manner dependent on the kinase PI3K and subsequent induction of the growth factor VEGFC, which functioned as an autocrine signal stimulating the receptor VEGFR3. We have demonstrated that the lateral and basolateral amygdala nuclei fail to form in neuroD2 null mice and neuroD2 heterozygotes have fewer neurons in this region. The significance of stereotactic biopsy in the diagnosis and treatment of central nervous system lymphomas Kinetic investigation of human 5-lipoxygenase with arachidonic acid.

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The precision of remote context memories does not require the hippocampus. We have used a piezoelectrically driven diaphragm to study the flow of solid helium through an array of capillaries. Thus, there appears to be a rise in the fetal level of cortisol with gestational age in late pregnancy, whether or not labor takes place.

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The hypothesis that was tested was whether the progression of symptomatic CVD or LED was more frequent or more rapid in patients with elevated plasma homocysteine levels. As a result, the sides of the tongue moved to form a narrow central groove. We assessed the potential for cross-amplification and whether loci were biased toward exons, as compared to markers derived from genomic DNA. The role of soluble adhesion molecules in evaluating endothelial cell activation in preeclampsia.

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Correlation of fine structure with neurotransmitter levels in acute brain oedema in cats. In anaesthetised, artificially ventilated guinea pigs, frequency-related NC bronchoconstrictor responses evoked by antidromic electrical stimulation of the vagus nerves were reduced by BW443C81 (100 micrograms/kg/min i.v. They may also induce the hyper-reactivity reaction and then become the reason of allergic or autoagression diseases. The relationships between calprotectin levels and Candida counts were assessed by using the Spearman rank correlation test.

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Both 2-L polyethylene glycol with ascorbic acid (2-L PEG/Asc) and sodium picosulfate with magnesium citrate (SP/MC) are low-volume combined agents for colonic preparation. Instead the ability to signal differentiation correlated with structural features shared by the EpoR, GMER, and E/beta receptors.

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New Echocardiographic Tehniques in Pulmonary Arterial Hypertension vs. Fourteen days after tumor inoculation, the mice with more than 2 mm diameter tumors were given an intravenous injection of 1 mg/kg of free TPP or TPP loaded into control PEG-PE micelles or into mAb 2C5-PEG-PE tumor-targeted immunomicelles. Elastomeric microFNs localized chemical reactions between the biomolecules and the surface, requiring only microliters of reagent to cover square millimeter-sized areas.

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Reduced cancer morbidity and mortality in a prospective cohort of women with distal forearm fractures. Auxin stimulates Aux/IAA degradation by promoting the interaction between a ubiquitin protein ligase (E3) called SCF(TIR1) and the Aux/IAA protein.

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Nickel subsulfide (Ni3S2), nickel sulfate (NiSO4), nickel chloride (NiCl2), and nickel oxide (NiO), are four compounds encountered by workers in the nickel-refining and electroplating industries. The activity of the selenium-independent glutathione peroxidase was increased, whereas those of catalase, glutathione reductase and the selenium-dependent glutathione peroxidase were unaffected.

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The absence of a non-treated group of women with endometriomas as a further control prevents comment on the presence of a progressive decline in ovarian reserve related to endometrioma per se. Moreover, this study showed that Mg depletion induces modification of nutrient uptake, especially Zn and Mn.

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Critical illness--a lived reality for patients and their families. Translocation and compartmentation of adenine nucleotides in mitochondria

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Simultaneous quantification of eleven bioactive components of male flowers of Eucommia ulmoides oliver by HPLC and their quality evaluation by chemical fingerprint analysis with hierarchical clustering analysis. Eye-tracking studies on exploration of faces and objects in autism provided important knowledge but only in a constraint condition (chin rest, total time looking at screen not reported), without studying potential differences between subjects with autism spectrum disorder (ASD) and controls in spontaneous visual attention toward a screen presenting these stimuli.

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Shared care planning between cardiac rehabilitation specialists and primary health providers could improve long-term adherence by ensuring continuity of care of patients who have completed a Phase 2 cardiac rehabilitation program, either facility or home based. This review details efforts to define the mechanism of this reaction and two emerging fields closely tied to this process.

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Biostatistical study on the arrangement of the superficial veins of the cubital fossa in Iraqis. The lysosomal enzymes separated by Percoll gradients showed three different types of distribution.

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Effects of asymmetrical triazine copper complexes on superoxide radical formation and on the Sendai virus multiplication. Together, our results suggest an important role for cross talk among Smad, p38 MAPK, JNK, and PI3K pathways in mediating the augmented expression of hAT(1)R following TGF-beta1 treatment in hPFB. No major differences in signal intensity, in its organ or intracellular distribution were observed between the postovulatory and the luteal phase of the cycle. We label the phosphatidylserine of rat brain microsomes through the base-exchange reaction and study the export of this lipid to mitochondria in a reconstituted system.

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