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Both painters and hairdressers displayed in their fingernails significantly lower percentages of sulfur, but higher percentages of carbon than unexposed controls. Bioavailability and phase II study of oral UFT plus leucovorin in patients with relapsed or refractory colorectal cancer. The defective macrophage migration in PAI-1-deficient mice can be restored by wild-type but not by a mutant PAI-1 that does not interact with LRP. Formation of nitro products from the gas-phase OH radical-initiated reactions of toluene, naphthalene, and biphenyl: effect of NO2 concentration. Because soy and elemental formulas are nonlactose-containing diets, the role of lactose in facilitating the intestinal absorption of minerals is of considerable nutritional importance.

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In the rainbow trout, however, immunosuppression was evident only at doses of TCDD approaching the 80-day, single-dose, parenteral LD50 of 20 micrograms/kg. Only in rare cases diagnosis could be made immediately on the basis of clinical symptoms. Most gelatinases, except for the 88- and 84-kDa gelatinases, were abolished by pretreatment with EDTA or phenanthroline, but not by pretreatment with a serine/threonine protease inhibitor. Opi1 also interacts with a newly identified functional domain of the transcriptional activator Ino2 (RID, repressor interaction domain). The article provides data on the pathogenesis, hemodynamics and the contractile function of the myocardium in chronic diseases of the lungs aggravated with pulmonary hypertension.

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Cortistatin overexpression in transgenic mice produces deficits in synaptic plasticity and learning. One-electron transfer reactions of diquat radical to different reduction intermediates of oxygen. Taurine, methionine, cysteine, lysine and ornithine levels were higher in yoked rats at the late phase while tyrosine was higher in yoked rats during the early phase. Writing for publication, in the nursing profession, is considered essential for the development of the profession and individual career advancement.

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In contrast, the 5-lipoxygenase (5-LO) inhibitor ZM 230,487 significantly decreased HO-1, iNOS and nitrite, which were not affected by zileuton. Revealing of the above variants allows one to determine the time of the antenatal damage of developing placenta. To investigate this possibility, we established a packaging cell line in which both wild-type and mutant Env proteins could be expressed simultaneously in a single cell. Administration at the acrophase of endogenous glucocorticoids significantly attenuated Dex-induced wasting of the gastrocnemius (Ga) and tibialis anterior (TA) muscles that comprise mostly fast-twitch muscle fibers. Four other, unrelated DR17-binding peptides showed the same pH-dependent binding characteristics as p3-13.

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Although the molecular pathways that regulate protein levels are well-studied, the functional implications of RNA accumulation and its regulatory mechanisms in cardiomyocytes remain elusive. A mass spectrometer of reversed geometry, which permits ion selection according to its mass-to-charge ratio before the ions enter the electric sector, was used to isolate the ion corresponding to the mass of each particular sidechain. The sedimentable sterols in gallstone patients before and during ursodeoxycholic acid and simvastatin treatments. Some types of toxicity observed during therapy with these drugs have gained much attention. Peer-reviewed literature suggests that olopatadine is clinically superior to the other anti-allergic molecules because of its strong anti-histaminic qualities and its unique ocular mast cell stabilizing properties.

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Data collected included co-morbidities (diabetes mellitus, hypertension, congestive heart failure), creatinine clearance (CLCR), concomitant treatment with potentially nephrotoxic drugs, vancomycin trough concentrations, total daily dose, and duration of therapy. Infertility treatment after conservative management of borderline ovarian tumors. Characterization of 5-HT1A receptor functional coupling in cells expressing the human 5-HT1A receptor as assessed with the cytosensor microphysiometer. The authors presented an analysis of 10 cases of eosinophilic fasciitis (EF): 6 men and 4 women aged 18 to 55. The antihypertensive action of beta-antagonists may be in part due to blockade of these facilitatory presynaptic beta-adrenoceptors.

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It was found that the shed snakeskin became more permeable after Azone or lauryl alcohol pretreatment, with a greater permeability increase for more hydrophilic and larger-molecular size permeants. Patients with locally advanced disease who are otherwise candidates for operation have a significantly higher response rate to chemotherapy and tolerate the treatment reasonably well. Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin. In this paper, we carry out an in-depth theoretical investigation for inference with missing response and covariate data for general regression models.

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Additional findings of note are increases in activity in the frontal lobes, particularly the anterior cingulate cortex, as well as deactivation of the limbic system, particularly the hippocampus. Assertion modeling and stimuli effects on assertive behavior and self-efficacy in adolescents. The RapID-ANA System (Innovative Diagnostics Systems, Inc., Atlanta, Ga.) was used to test 102 strains of 14 species of phenotypically similar bile-inhibited Bacteroides from humans. In this phase I trial, RD of cisplatin was identified as 20 mg/m(2).

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Peptides 5 (Ac-SHAVAS-NH2) and 6 (Ac-SHAVSA-NH2) were found to be more effective than the parent peptide 1 in decreasing the resistance of the cell monolayer. This formulation maintained a significant level of AZT in tissues rich in galactose specific receptors and had a prolonged residence in the body resulting in enhanced half-life of AZT. Its performance has been assessed with human blood at 37 degrees C and in use with Antarctic fish blood (Pagothenia borchgrevinki) at -1.5 degrees C. CD95 (Fas) may control the expansion of activated T cells after elimination of bacteria in murine listeriosis. However, a considerable degree of proofreading can be obtained in less strongly driven systems, dissipation only 0.1-1 kT/step.

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The second stage of the process was characterized by an inversion in the balance in activity between these signal transduction pathways and by a concomitant decrease in apoptosis. Health-care workers (HCWs), due to their regular contact with patients are at a high-risk of acquiring this disease. Chronic Kidney Disease (CKD) is a major non-communicable chronic disease that is associated with adverse clinical and economic outcomes. The ileum had blunted villi, a decrease in villus-crypt ratio and a mild edema in the lamina propria.

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The analgesic action with a lower dose occurs earlier than the anti-inflammatory action. Archeological and ethnographical data suggest that vilca was used and is still used by native shamans as a sacred seed in South America, due to its hallucinogenic effects. The purpose of this study was, therefore, to determine whether monoamine- and histamine-synthesizing enzymes and neurotransmitters exist within neurons of adult human cardiac ganglia. For patients with resected rectal cancer who have already received 5-FU-based neoadjuvant chemoradiotherapy, postoperative 5-FU-based chemotherapy prolongs the CSS of groups in ypStage III. The diagnosis was confirmed by surgical exploration in all 11 patients.

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Our model is fully analytical, yet it accurately reproduces the force-extension curves, as well as the transient kinetic behavior, seen in DNA overstretching experiments. In incubating hens, the dopaminergic inhibition is diminished, allowing for the increased PRL level observed during incubation.

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RNase protection analysis showed M-CSF mRNA already in unstimulated astrocytes without striking up-regulation by the stimuli. This study examines the frequency of spontaneous abortions in pregnancies achieved by artificial inseminations with donor semen (AID), with special respect to the use of cryopreserved semen and ovulation induction with clomiphene citrate. Treatment of bronchial asthma with small doses of papaverine combined with beta stimulators The hybrid structures exhibits a turn-on electrical field of 4.36 V/microm and a field enhancement factor of 1157, which benefit from the high-aspect ratios of both ZnO nanowires and carbon cloth.

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Beam line shutters and the medical room walls provide sufficient shielding to enable access and use of the facility without affecting other experiments or normal operation of the multipurpose research reactor at MIT. Nosocomial bacteriuria in elderly inpatients may be leading to considerable antibiotic overuse: an audit of current management practice in a secondary level care hospital in New Zealand.

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Delivery and scavenging system for small animal inhalational anesthesia. Special delivery: Liposomal drug-delivery systems in which prodrugs are activated specifically by disease-associated enzymes have great potential for the treatment of severe diseases, such as cancer.

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Effect of iopanoic acid on radioiodine therapy of hyperthyroidism: long-term outcome of a randomized controlled trial. Although early mortality in severe psychiatric illness is linked to smoking and alcohol, to our knowledge, no studies have comprehensively characterized substance use behavior in severe psychotic illness. Are congenital virus infections possible in successive pregnancies?

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Penetrating lung trauma in the majority of patients may be treated conservatively with a low incidence of infection or complication. At 11:00 h on the day of the experiments, normally fed rats received an intracerebroventricular injection of artificial cerebrospinal fluid, anti-leptin serum, or normal rabbit serum. Provider advertisements for stereotactic radiation were prominent and aggressive. Toxicoproteomics: a parallel approach to identifying biomarkers.

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Logistic multivariate analysis was used to predict response to the PFT. The influence of methotrexate and of betamethasone on a following phototoxic reaction to 8-methoxypsoralen and long-wave ultraviolet light (PUVA) was studied in the mouse. Association between oral HSV-1 and survival in allogeneic hematopoietic stem cell transplanted patients.

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The release of gentamicin after total hip replacement using low or high viscosity bone cement. However, the evaluation of biological activity of the XyNRPSA product suggests that it is neither a compound with antifungal activity nor a siderophore. We measured indinavir C(trough)/C(2h), serum creatinine, pyuria, blood pressure (BP), weight and HIV RNA. The time required for the exchange of 50 per cent of the red cell potassium is calculated to be 43 hours. Immunophenotyping of peroxidase-negative acute leukaemias using immunoalkaline phosphatase (APAAP) method.

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HIF-1 alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages. Today there is a small group of patients showing a large susceptibility to caries. In this review, we analyze the participation of thyroid hormones on ROS production and oxidative stress, and the way the changes in thyroid status in aging are involved in neurodegenerative diseases. Mitral/tufted cells in the olfactory bulb and projection neurons (PNs) in the insect antennal lobe are involved in complex synaptic interactions with inhibitory interneurons to help shape their odor-evoked responses.

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Tumor tissues were harvested from patients immediately before they entered a cisplatin- or carboplatin-based treatment protocol. Long-term followup of a bladder carcinoma cohort: questionable value of radical radiotherapy. The thienopyridine clopidogrel is a pro-drug metabolised in the liver via the cytochrome P450 (CYP) 3A4 system to the active compound which inhibits the P2Y(12) ADP platelet receptor. The first of these activities was inhibited by Z-Pro-prolinal, demonstrated activity towards the thyroliberin analogue, 7-(pyroglutamyl-histidyl-prolyl)-4-methylcoumarin (Glp-His-Pro-NH-Mec), and was catalytically enhanced under reduced assay conditions. Adenovirus-mediated expression of pig alpha(1, 3) galactosyltransferase reconstructs Gal alpha(1, 3) gal epitope on the surface of human tumor cells.

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Two other reports have appeared in the literature which link the development of keratoacanthoma with psoriasis and pustular psoriasis. Fourteen years of experience in uncontrolled organ donation after cardio-circulatory death. We demonstrate that very few (2-4) quantum dots as a gain medium are sufficient to realize a photonic-crystal laser based on a high-quality nanocavity.

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Nuclei of both types of polyp had only a small number of large-sized NORs in a clustered distribution. Data from a prospective study of 17 patients residing in healthcare facilities indicated that supplementary tests remain predictive of a positive response to shunt insertion but cannot predict whether a favorable outcome will be sustained in a population of patients who have been confined to a wheelchair for a prolonged period of time. Moreover, loss of Barhl2 leads to the absence of thalamocortical axon projections, the loss of habenular afferents and efferents, and a gross diminution of the pineal gland.

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Effect of hyaluronic acid on human chondrocyte cell lines from articular cartilage. The priorities for such a network have been listed as follows: The present organization for the MCH website at the Pasteur Institute in Paris should be adapted to better promote collaboration between scientists from industrialized and developing countries. Switching NVP to RPV could result in decreased RPV exposure with subsequent virological failure and dyslipidemia because NVP is regarded as the least dyslipidemic, non-nucleoside, reverse transcriptase inhibitor. None of the seven patients had any suspicion of RO, based on computed tomography (CT). Purified gC (Delta33-116) was more resistant to PI-88 than unaltered protein in its binding to cells.

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The purpose of respiratory support in FC is to reduce atelectasis and the resulting shunt, and to improve removal of mucus from airways. However, it is important to recognize some specific conditions with a unique pattern of tracer uptake, especially in extraosseous locations as they are not related to primary neoplasm or metastases. Photoresponsive properties of poly(N-isopropylacrylamide) hydrogel partly modified with spirobenzopyran. The different functions of pain are presented, especially regarding the extent to which pain represents an experience that constitutes both the body and the identity.

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To evaluate velocity waveforms in muscle and to create a tool and algorithm for computing and analyzing muscle inertial forces derived from 2D phase contrast (PC) magnetic resonance imaging (MRI). Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.

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In this sample of 6-year-old children, greater BMI, weight and BSA were associated with wider retinal venules, while greater BMI and larger waist circumference were associated with narrower retinal arterioles. The subfamily of claudins forming charge- and size-selective pores provides selective paracellular diffusion.

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LC-MS/MS analysis showed that the amino acid sequences of p60 partially coincided with those of the Paramecium tetraurelia unnamed protein homologous to DEAD-box RNA helicase. This should be added to the list of cutaneous side-effects of this class of chemotherapeutic agents. The blood plasma peptide fractions labelled with 3H-leucine after chronic administration of ethanol or acetaldehyde in rats have been analysed. The AS-OCT showed obstruction of the glaucoma drainage device by iris tissue and enabled precise placement of the iridectomy immediately overlying the tube orifice. Plants possess a number of adaptive, avoidance, or acclimation mechanisms to cope with HT situations.

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