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Epzicom (Abacavir)

Epzicom is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), lamivudine (Epivir), emtricitabine (Emtriva), and stavudine (Zerit). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, Epzicom is converted within the body to its active form (carbovir triphosphate). This active form is similar to a compound (deoxyguanosine triphosphate), a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses carbovir triphosphate instead of deoxyguanosine triphosphate for making DNA, and it is the carbovir triphosphate that interferes with the reverse transcriptase. Epzicom does not kill existing HIV virus, and it is not a cure for HIV. The FDA approved Epzicom in December 1998.

Other names for this medication:
Abacavir, Abalam, Epzicom, Kivexa, Abamune, Virol, Ziagen,

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Differences in the inferred truncation sites of PrPd are found for different strains of sheep TSEs and for different infected cell types within individual strains. We investigated the effects of plant density on plant size, leaf total soluble protein content, and constitutive and wound-induced levels of proteinaceous trypsin inhibitors in pot-grown Brassica napus seedlings in two greenhouse studies. Partial disassembly of the Hox gene complex (HOM-C) in Caenorhabditis elegans and in two different Drosophila lineages, however, calls into question whether this cluster organization is absolutely required for proper function. Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci.

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This promotes the persistence and/or reacquisition of stem cell properties in Lgr5-negative progenitor cells that have exited the stem cell niche. Selection of grapevine leaf varieties for culinary process based on phytochemical composition and antioxidant properties.

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After furosemide administration, glomerular filtration rate, urine flow, urine sodium excretion, free water clearance, urine pH, plasma renin activity and plasma aldosterone exhibited the same behavior in the presence of both serum insulin concentrations. Currently, no treatments that increase utrophin protein expression exist.

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The dopamine (DA) receptor blocking effect of neuroleptics is believed to be responsible for their antipsychotic effect. The quality of the socket fixation has been improved by the use of new methods and designs, while a new technique of stem fixation has all but eliminated the loosening. Concentrations of PP5 showed a skewed distribution and rose progressively to reach a plateau in the last four weeks of pregnancy.

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Pretraining and posttraining examinations were given in these areas to analyze the degree of knowledge gained by these methods. HISTIDINE, PHENYLALANINE, AND TYROSINE METABOLISM IN KWASHIORKOR. The expression of occludin in polyp tissues was examined before and after treatment using immunohistochemical staining and quantitative reverse transcription polymerase chain reaction.

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At the beginning of training, when the highest proportion of responses occurred soon after the US onset, escape latencies were shorter in groups trained with shorter CS-US intervals and the more intense CS. After intravenous injection of 123I-labelled purified human SAP there was specific uptake into amyloid deposits in all affected patients, 7 with systemic AL amyloid, 5 with AA amyloid, and 2 with beta 2M amyloid, in contrast to the complete absence of any tissue localisation in 5 control subjects. When endothelial cells are incubated with this lipoprotein in pathophysiologic amounts, the cells are activated. The dental exam was completed by a single dentist at a third location. Prospects for the possible development of a cross-reactive vaccine have increased since the demonstration of highly conserved DNA sequences in the envelope region of several divergent HTLV-III strains.

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A greater prevalence of aneurysmal bone cysts in young individuals is associated with skeletal growth and immaturity. The correlation coefficient between the PedQL and KIDSCREEN-52 dimensions were high for the assessments of similar constructs. The paroxysmal benign nystagmus disappeared after transtympanic nerve neurectomy of the inferior branch of the vestibular nerve (Gacek 1974). Although circulatory diseases have been the major cause of mortality in men and women in the Brazilian population, with a greater participation by cerebrovascular diseases, a trend towards a decrease in the risk of death from these causes is being observed.

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Laterality, or the tendency for acupoints on the right or left side of the body to produce different physiological effects, is an important aspect of acupoint specificity. The generation of C5fr may contribute to the pathogenesis of adult respiratory distress syndrome and other diseases. It was hypothesized that those with systemic diseases such as diabetes mellitus would likely have higher prevalence rates of self-reported depressive symptoms than those diagnosed with nonsystemic diseases in part due to the disability conferred by their diagnosis. Image processing for femoral endosteal anatomy detection: description and testing of a computed tomography based program.

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After diagnostic workup and stabilization a small bowel resection with end to end anastomosis was performed. Moreover, in ratio of WSC occurs prolongation of sleep and shortening of wakefulness. In contrast, cartilage removed from an unaffected joint in the same animal showed no chondrocyte activation. The level of its quenching on DNA correlated with the quantity of the antibiotic bound to it.

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Presently, ciprofloxacin, azithromycin, and ceftriaxone serve as the mainstays of treatment, although growing evidence has documented decreased susceptibility or full resistance to these agents in some regions. Using quantitative PCR, the level of MK mRNA was significantly increased at 4h after 9cRA application.

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In particular, steamed samples showed a significantly higher increase of centre frequency, in accordance with a more pronounced isomerization and changes in colour parameters. This article describes an alignment method that uses an image-based coordinate system to compensate for shifts of the pupil center as well as cyclorotation. However, it is an effective and safe route for continuous administration for individuals requiring palliative care. crassa are involved in light-dependent formation of protoperithecia and conidia.

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Oral glucose tolerance curve and hypoglycemias in the fed state. bethanechol might be responsible for a non-voiding outcome after bethanechol injection in patients with complete cauda equina lesions, despite a positive bethanechol test. This radiological imaging procedure has been provided for dentistry and is comparable to computed tomography (CT) in medicine. It is shown that the low-density Ohmically heated tokamak plasmas have streamerlike eddies at the outer region at normalized minor radius of about 0.7 and high-frequency zonal flows of large amplitudes in the core. Finally, these findings suggest that human patterns cannot be addressed solely by traditional, small-scale investigations on single populations.

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Dil-labeled cells, without an epithelial phenotype, remained present in the midline of the completely fused palate. Electron microscopy showed that the neocentromere formed microtubule-associated kinetochores with normal morphology and of the same size as the kinetochores of other large chromosomes. Because of severe emphysema and other multiple comorbidities, left S3 segmentectomy with hilar lymph node sampling was performed using video-assisted thoracic surgery (VATS).

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Blood pressure changes induced by morphine and Tyr.D-Ala.Gly.MePhe.Gly-ol (DAGOL), but not EKC, were blocked by N-methylnalorphine. Present data suggest that speaking different languages on a regular basis may additionally contribute to the build-up of cognitive reserve in old age.

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The propionylation/FAB-MS procedure has been combined with gas-phase sequencing strategies and shows promise for defining the sites of glycosylation of O-GlcNAc glycopeptides that are available in limited quantities. This cross-reactivity suggests that some epitopes in chick beta-keratin are also present in gecko setae. False color representation of a dye distance map with four osteoblasts. Muscle biopsy revealed features characteristic of acid maltase deficiency.

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Our extensive preclinical studies have shown that (64)Cu-TP3805 has a high affinity for VPAC1, is stable in vivo, and has the ability to distinguish spontaneously grown malignant BC masses from benign lesions. The effectiveness of using drama-based evaluation methods is also discussed.

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NIDDM was defined by a history of physician diagnosed diabetes or use of antihyperglycemics. In this research, Langmuir film technique, atomic force microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR) are employed for a systematic investigation on the effects of cholesterol component on the molecular interactions between a prototype antineoplastic drug (paclitaxel) and 1,2-dipalmitoyl-sn-glycerol-3-phosphocholine (DPPC) within the cell membrane by using the lipid monolayer at the air-water interface as a model of the lipid bilayer membrane and the biological cell membrane. Proposed guidelines were recommended to assist audiologists in this endeavour.

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In addition, the esterase activity in rat and guinea pig blood was localized in plasma and not in RBC. The simultaneous measurement of these two different adducts thus offers an opportunity to investigate the role of both ABP and acetylator phenotype in bladder carcinogenesis.

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Therefore, we investigated impact of age on outcome in advanced ovarian cancer. The forward and the backward waves cross over, forming a hysteresis loop. administration of PGE2, whereas pretreatment with 5,6-dihydroxytryptamine (5,6-DHT) plus p-chlorophenylalanine (PCPA) had no effect.

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Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate. This work examines NiTi foams that have been treated using a new oxidation treatment for obtaining Ni-free surfaces that could allow the ingrowth of living tissue, thereby increasing the mechanical anchorage of implants.

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A total of about 25,000 specialists are now working in the occupational health field. Paraneoplastic pemphigus (PNP) seems to be a separate autoimmune mucocutaneous disease. Sex-based disparities in cardioprotective medication use in adults with diabetes. Our data suggest that IK inhibits growth and induces apoptosis in melanoma cells via activation of ROS-mediated caspase-dependent and -independent pathways.

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SEM studies present a three-dimensional vision of the filamentous material that confirms and clarifies the cellular deformation as a whole. Discussed is the problem as to whether the cross reaction is due to common or similar antigenic determinants in the parasites and in some specific spermatozoid antigens. A thin-layer amperometric sensor for hydrogen sulfide: the use of microelectrodes to achieve a membrane-independent response for Clark-type sensors. The oligosaccharides were structurally characterized by fast atom bombardment-mass spectroscopy, nuclear magnetic resonance spectroscopy, and glycosyl-linkage composition analysis.

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Opiate stimulation of prolactin secretion is reversed by ovarian hormone treatment. Trigger-free anesthetic management in congenital long QT syndrome. Having established these ideas, the review provides an illustration of how a combination of action research themes and qualitative research techniques has been used to influence and support heads of education and welfare in UK soccer academies across the north-west of England. The hypothesis that the enlarged brain size of the primates was selected for by social, rather than purely ecological, factors has been strongly influential in studies of primate cognition and behaviour over the past two decades. Regulation of hepatocyte engraftment and proliferation after cytotoxic drug-induced perturbation of the rat liver.

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Autism spectrum disorder (ASD) and childhood onset schizophrenia (COS) are pediatric neurodevelopmental disorders associated with significant morbidity. Surgeons with endovascular skills can perform this procedure with superior results. All patients should be equipped with an emergency kit (antihistamine, corticosteroid).

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Robotics in microsurgery: use of a surgical robot to perform a free flap in a pig. Drug therapy in dental practice: nonopioid and opioid analgesics. The aim of the present study was to evaluate the marginal microleakage of the newest generation of composite resin restorative materials. Acute oral toxicity evaluation of biodegradable and pH-sensitive hydrogel based on polycaprolactone, poly(ethylene glycol) and methylacrylic acid (MAA). The nucleotide-free model features a large cavity detected in the protein core into which ligands of different size were successfully docked.

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Early studies had indicated that O-linked N-acetyl galactosamine was the sole serologic Tn determinant, but more recently O-linked NeuNAc alpha 2, 6GalNAc also has been implicated as a Tn antigen (sialosyl-Tn). The authors sought to analyze prospectively the outcome of surgery for complex spinal deformity in the pediatric and young adult populations. Although an aim of the program was to reduce the frequency of contacts for individual therapy, these contacts did not decline over the follow-up period. In addition to fluid dynamic advantages proposed by de Leval, total right heart bypass may address an emerging important issue after repair of single ventricle: late atrial arrhythmias.

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After hyperopic laser in situ keratomileusis there was no significant difference in Goldmann applanation tonometry between retreated and primary LASIK eyes. Statistical analyses were performed using the Kaplan-Meier and Cox proportional hazards regression methods. The results of the study demonstrate that 3DHRAM can diagnose excessive perineal descent with the same degree of reliability as defaecography. Airway reactivity as assessed by methacholine challenge did not explain the difference in response to tantalum in the third group.

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In the conditional gain-of-function GVG-NtMEK2(DD) transgenic tobacco, induction of WIPK expression is dependent on the ROS generation in chloroplasts. The value of different diagnostic treatment and preventive programmes. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register which comprises references identified from comprehensive electronic database handsearches of relevant journal and abstract books of conference proceedings.Date of most recent search: May 2008

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Therefore, the outcome of antigen recognition by T cells is determined by the interaction of CD28 or CTLA-4 on the T cells with B7 molecules. Needle biopsy should be done, when a hepatic cyst is detected by ultrasound, when there is suspicion of malignancy, and when a parasitic lesion has been excluded. Large and cubic crystals were the best defined on the membrane treated at 1600 mg/L of CaCl2. coli H-protein shows extensive homology with the H-proteins from the pea (Pisum sativum) and the chicken liver GCV enzyme complexes.

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This was done by hybridizing digested DNA on Southern blots with a series of subgenomic cloned fragments of AD169. Distribution of intramuscular and oral aminazin (20 mg/kg) in the brain, lungs, liver, kidneys, heart, ileum, blood and urine was studied in young and old male rats. A sample consisting of 2,111 children aged 6-59 months was obtained from the 2011 Nepal Demographic and Health Survey.

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Some were of bizarre waveform, in no way assisted vision, and were taken to be of primarily pathological origin and classified as tremors. Biotransformations of Bile Acids with Bacteria from Cayambe Slaughterhouse (Ecuador): Synthesis of Bendigoles. Vegetating and erosive lichen of the tongue and active chronic hepatitis.

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The sleep of patients in all three treatment groups, as measured by patient self-rating scales, substantially improved during the study, with loprazolam being superior to placebo for measures of sleep latency, satisfaction with sleep, number of nocturnal awakenings and feeling refreshed on waking. Thus, exercise and upright posture produce distinctive alterations in the thrombogenic potential of the blood that may influence the timing of clinical vascular events. Routine and population data are products of administrative systems and the nature, completeness and quality of data available to clinical and public health researchers are substantially impaired by market reforms. Iron and folic acid supplements almost doubled this increment to 349 ml of red cells. After growth on acetate three groups of Acinetobacter strains could be identified with respect to the excretion of a bioemulsifier.

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Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the PI3K/PKB and MEK/ERK 1/2 pathways. A pure potassium channel blocker was successful in inhibiting polymorphic ventricular tachycardia inducibility by prolongation of refractoriness. Our experience since the introduction of isoniazid (INH) into the treatment of tuberculous meningitis (April 1952 till December 21, 1953) These two novel compounds exhibit marked chemical and biological similarities to their endogenous prototype and they antagonize it being less active in inducing washed platelet aggregation through PAF receptors. On the inoculation site, the amount of the virus in the resistant wheat line (YW642) was much lower compared to the susceptible sib line (YW641).

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This may be caused by an increase in the extent of lophyl radical recombination within the solvent cage. The measured conversion efficiency is in good agreement with the conversion efficiency predicted by the effective-medium model. Medical history and ability to carry out daily activities were taken by trained medical personnel.

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We studied 60 eyes with different forms of keratoconus using the TMS-3 autotopographer, provided with a keratoconus screening program (using Smolek-Klyce methods) and the commercial version of the ultrasound biomicroscope (Paradigm UBM Plus Model P45) equipped with a 50-MHz probe, which was provided with our computer-assisted program. In mid 1990, an epidemic of fever affected a single village in Kaniyambadi Block, South India. Furthermore, a balance of glycosphingolipids, cholesterol, and caveolin-1 has been shown to be important in regulating caveolae endocytosis. Advanced Atherogenic Index for the Assessment of Consolidated Lipid Risk in Premature Coronary Artery Disease Patients in India. This was performed by employing (1)H nuclear magnetic resonance (NMR)-based metabonomics and denaturing gradient gel electrophoresis (DGGE) fingerprint of gut microbiota.

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The effect of power on the localization process of these optical self-trapped states at the edge of an AlGaAs waveguide array is investigated in detail. We identified age, size of the primary tumor and small vessel invasion as important prognostic factors for relapse in patients with stage I seminoma treated with surveillance. Docking of ligands to the minor or major groove of DNA has the effect that the intramolecular B-S transition remains visible as a distinct plateau in the force-extension trace. Fatty acids differentially affect serotonin receptor and transporter binding in the rat brain.

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This is one of the first examples of a motor to be implicated in the essential transport of a discreet fluzol tablets with windows cargo necessary for axon extension. Histologic development of a compact heterogeneous graft used in vertebral arthrodesis for scoliosis The rapid spread and the transmission to humans of avian influenza virus (H5N1) have induced world-wide fears of a new pandemic and raised concerns over the ability of standard influenza vaccine production methods to rapidly supply sufficient amounts of an effective vaccine. Their greater value mismatch was associated with a greater susceptibility to burnout and a stronger intention to quit for Generation X nurses.

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How rapidly virus is cleared is a function of initial viral load, viral replication rate, and efficiency of the immune response. Some problems of anatomical justification of the suture technic used for the artificial mitral valve The present study was conducted with a view to estimating the prevalence of dementia in Tribal Landlocked Elderly Population at high altitude and therefore to bazetham retard 0 4 mg draw some conclusions on the differential distribution of dementia across populations.

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Our results suggested that patients with multiple and positive vascular endothelial growth factor expression in the metastatic tumor will not dofil 150 mg receive benefit from metastasectomy. Increases in rCBF suggest a cellular and vascular compensatory process associated with incipient AD. Efficient ternary complex formation by Elk-1 is mediated by the B box, a conserved 21 amino acid region located 50 residues C-terminal to the Ets domain, which also acts to inhibit autonomous DNA binding. QUANTITATIVE ESTIMATION OF HUMAN SERUM HAPTOGLOBINS BY AN IMMUNOLOGICAL METHOD.

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Neural Dynamics of Emotional Salience Processing in Response to Voices during the Stages of Sleep. Accumulation and translocation of the environmental pollutants zinc, cadmium, lead, and copper, was evaluated in different lansoprazole side effects ukc portions of the plants at two harvesting times.

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The changing survival of patients with mycosis fungoides: a population-based assessment of trends in the United States. Twelve type I adult patients with relatively severe disease were commenced on a very low dose of 7.5U of alglucerase/imiglucerase per kg every two weeks (initially given thrice acetazolamide with sulfa allergy weekly and later weekly). To assess bone mass status in individuals, BMC index, as well as BMD, should be used, particularly with adults at the extremes of body size (the very small or very tall).

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The potencies of propranolol and CGP-12177 for antagonizing the behavioral effects of clenbuterol also were determined. Diagnostic value of the determination of serum alpha2-HS-glycoprotein A double-blind, placebo-controlled randomised repeat crossover Cu supplementation trial. In this study the clenching force was measured, which 12 patients used, while the needle-point tracing was in progress. The mechanisms of action of antibiotics on the hair cells ronaldo's second goal vs levantes of the organ of Corti are discussed.

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It therefore behooves authors to strive to improve reporting transparency, journals to support such industry, and readers to remain mindful that the cumulative survival is an estimate, ie, a reflection of reality. The concentration of gluconeogenic substrates is lower in the blood of starved PDHK4-/- gengar acyclovir dosing mice, consistent with reduced formation in peripheral tissues. The host factors of ageing, alcohol consumption, and male sex have a stronger association with fibrosis progression than virological factors in HCV infection. In this paper we demonstrate that the apparent pattern of gas exchange in insects, as observed using flow-through respirometry, is strongly affected by the rate of flow of air through the system. Poly-lactic acid (PLA), poly-lactic-co-glycolic acid (PLGA), and chitosan (CS) were chosen to prepare NPs.

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Regulation of heart specific phosphorylase a by AMP, glucose-6-phosphate and glucose. We mailed a questionnaire to 284 members of the Danish Paraplegic Association who clarithromycin side effects shaking in dogs met the inclusion criteria (member for at least 10 years).

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The A-minor I water bridge, however, does not appear to stabilize the tertiary contact, and its role is to provide structural flexibility to this binding pattern within the context of the RNA structure. Two-dimensional blue native/SDS-PAGE analysis of whole cell lysate protein complexes of rice in response to salt stress. Finally, in non-monotonic neurons, tonal maskers at the high-frequency edge of the excitatory response area produced enhanced responses to tonal zytiga prostate drug finasteride signals on the same side of the response area as the masker.