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Circulating histamine and neutrophil chemotactic activity during allergen-induced asthma: the effect of inhaled antihistamines and anti-allergic compounds. The acceptor specificity of three major isoforms of UDP-GalNAc:polypeptide N-acetylgalactosaminyltranferases (murine recombinant proteins GaNTase-T1, -T2 and -T3) was investigated using the synthetic peptide (GTTPSPVPTTSTTSAP) containing clusters of threonine residues mimicking the mucin tandem repeat unit of MUC5AC. A detailed review of the physiologic effects of antihypertensive medications, as well as a critique of the clinical trials and some of the problems noted in the pharmacologic management of hypertension, is presented.

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Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels. Despite these advantages, issues relating to inconsistent immunogenicity and immune interference remain to be addressed. Norway rat pups have an enhanced olfactory bulb response to odors which they have learned to prefer early in life. Cigarette smoke induces alterations in the drug-binding properties of human serum albumin. Possible species differences in the physiological factors which control permeability are discussed.

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We show here that this pathway can be inhibited in Arabidopsis thaliana by expression of a ubiquitin variant that contains Arg instead of Lys at position 48 (ubR48). Diagnosis was made through postoperative pathological examination. Expression of a protein fragment containing four N-terminal MBRs (metal-binding repeats) of ATP7B (MBR1-4) protects cells from the toxic effects of cisplatin. The patient suffered from an association of septic and urate-crystal-induced arthritis. Spontaneous remission is a rare feature in mitochondrial liver diseases, and early identification of TRMU mutations could impact on clinical management.

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A prospective 1 year study of all patients hospitalized with CAP in the Negev region of Israel. Solid-phase extraction and reverse-phase high performance liquid chromatography. We report a higher incidence of IE than described by the French national study of 2008. Pharmacologic treatment of SARS: current knowledge and recommendations. Daphnane diterpene esters have previously been shown to have antineoplastic activity in vivo against the growth of P-388 lymphocytic leukemia cells.

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The effect of a chronic mild elevation of plasma triiodothyronine levels upon the contractile properties and fibre distribution of skeletal muscle was studied. Disseminated calcitonin-poor medullary thyroid carcinoma in a patient with calcitonin-rich primary tumor. It is suggested that the altered peptides derived from CII263-272 with substitution of amino acids responsible for TCR contact might be of inhibitory effect on T-cell responses. Charts were reviewed to assess impact of therapy on survival and patterns of recurrence in those that died of disease.

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Cancer stem cells (CSCs) represent a distinct subpopulation of cancer cells which are shown to be relatively resistant to conventional anticancer therapies and have been correlated to disease recurrence. On the other hand, the use of drugs able to reduce exaggerated release of CKs by M/M is suggested in AIDS patients in order to prevent a further aggravation of the clinical condition. Two recent studies that involve perturbing tumour blood supply provide new hope for anti-cancer therapies.

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Metabolites from 1H MRS: N-acetyl aspartate (NA), creatine (CR), choline-containing compounds (CHO), myoinositol (MI), glutamine/glutamate (GLX), lactate, and lipids. Here, by sequencing the sRNAs and mRNAs of WSSV-infected Chinese shrimp (Fenneropenaeus chinensis), we found that the viral transcripts were universally targeted by WSSV-derived siRNAs, supporting a pivotal role for RNAi in the anti-viral immunity of shrimp. We investigated the role of gelsolin and its cleavage product in apoptosis of vascular smooth muscle cells (SMC) induced by the proinflammatory cytokines interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha). amoena is monoecious and as a consequence, the species was transferred to Vasotrema Stunkard, 1928 (Spirorchiidae) as V. Endothelial expression of Fc gamma receptor IIb in the full-term human placenta.

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Copper complexes have radiation protection and radiation recovery activities and cause rapid recovery of immunocompetence and radiation-induced damage to cells and tissues. We investigated the CYP450 protein expression in the in vivo hepatotoxicity of rats induced by CCl(4). Evolutionary trees based on codon and aminoacid usage are consistent with traditional phylogenies of species within the genus.

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Idiopathic pulmonary fibrosis (IPF) is a progressive diffuse lung disease associated with an increased risk of lung cancer. Five courses of BEP therapy were performed, and CT of the chest revealed reduction in the anterior mediastinal mass and disappearance of the multiple lung metastases. Incident falls in 1 year were determined by telephone followup every 4 months.

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The data highlight further the complex pathophysiological implications of microalbuminuria in hypertension. Survival among patients with adenocarcinoma of the pancreas: a population-based study (United States). This anomaly directly connects the gallbladder to the bile ducts, draining a portion of the right lobe of the liver. Blocking oligos can improve the hybridization efficiency of dsDNA to about 2/3 that of ssDNA. The biologic objectives of root canal therapy: meeting the standard.

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Over-expression and refolding of isotopically labeled recombinant catalytic domain of human macrophage elastase (MMP-12) for NMR studies. ActinomycinD experiments revealed that AngII stabilized cyclinD1 mRNA in human mesangial cells via HuR. Antidepressant-like effects of the traditional Chinese medicine kami-shoyo-san in rats. Expression of and relationship between caspase-1 and interleukin-18 mRNA in brain tissue of hypoxic-ischemic neonatal rats

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Patients with OAB symptoms were randomised to double-blind treatment with 0.1 mg of imidafenacin twice daily (group A) or propiverine 20 mg once daily (group B) for 12-week regimen, and assessed for efficacy and safety. Effects of dynorphin1-13 on opiate binding and dopamine and GABA uptake in stroked cat brain. Using a longitudinal study design, 123 young adults-identified in adolescence as at-risk for high school dropout-were examined for the effects of multi-domain childhood victimization on emotional distress and suicide risk, net of adolescent risk and protective factors, including family dysfunction. We derived the three point extension (TPE) of the hypernetted chain/mean spherical approximation (TPE-HNC/MSA) and Poisson-Boltzmann (TPE-PB) integral equations.

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Our results show that EEG features recorded in epileptogenic areas are largely coupled with rCBF increase. Quantification of calcium in solitary pulmonary nodules using single- and dual-energy CT. Dissolution profiles for alginate matrices of different viscosities were similar in acid but differed upon increase of pH. Thus, prevention of osteoporosis by identifying risk factors or risk indicators, as well as the development of new treatment strategies, are major issues.

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A novel device and procedure for the collection and isolation of microvolumes of plasma have been developed and two pilot rodent PK studies have been completed. Intrathecal midazolam as an adjuvant has been used and shown to improve the quality of spinal anaesthesia and prolong the duration of post-operative analgesia. Equivalent forms of the MIS were given at the beginning and end of the testing session to assess alternate forms reliability. Fibrogenesis represents a complex process in which focal adhesion kinase (FAK) plays an important role. Hormonal interactions and glucocorticoid receptors in patients with the nephrotic syndrome

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In one group the tumour was excised totally, in the other group tumour material was left. The biology of parasites from the genus Argulus and a review of the interactions with its host. The RAND Future Elderly Model illustrates important principles about the relation among medical technologies, health spending, and health. Sodium salicylate inhibits expression of COX-2 through suppression of ERK and subsequent NF-kappaB activation in rat ventricular cardiomyocytes.

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However, in contrast to that observed for other RNA and DNA viruses, dengue virus capsid degradation was not responsible for genome uncoating. These results support legislative interventions in populations without helmet legislation. By contrast, deletion of almost the entire extracellular domain of the receptor (TM409 mutant) totally impairs receptor function, thus confirming a role of the juxtamembrane extracellular region in receptor function. To compare the safety and effectiveness of flexible ureteroscopy (F-URS) with transperitoneal laparoscopic ureterolithotomy (TPLU) in cases of obstructive pyelonephritis secondary to large proximal ureteral stones.

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Testicular androgen production by the Leydig cells is almost entirely dependent on LH/hCG action, while in the ovary LH triggers both oestrogen and progestin secretion and ovulation of the Graaffian follicles. To determine the adequacy of reduction and the soundness of the technique of primary internal fixation, the authors studied prospectively 96 femoral neck fractures over 6 1/2 years. Inhibition of human granulocyte chemotaxis towards casein was observed in the presence of both the mu and kappa opioid receptor agonists, which, per se, exhibited chemokinetic activity. The five components of the Bishop score were assessed by digital examination and cervical length was measured by transvaginal ultrasonography in 177 women with a single pregnancy, 36-42 weeks of gestation, and a live fetus in cephalic presentation before induction of labor. Regulation of ventilation during hemorrhage and its alterations in response to CO 2 .

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With this integrated iter it is possible to reduce false negative and positive findings and consequently to obtain a non correct diagnosis and to plane a more precise therapy. The Relationship between C-Reactive Protein Level and Discharge Outcome in Patients with Acute Ischemic Stroke.

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Peptide antigens are presented to T cells by major histocompatibility complex (MHC) molecules, with endogenous peptides presented by MHC class I and exogenous peptides presented by MHC class II. To investigate the clinical significance and therapeutic efficacy of small follicular ovulation (SFO) in infertile women and recurrent spontaneous abortion patients.

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Over a course of 72 h, FN (10 micro g/ml) caused both increased survival and proliferation of NCI-H446 cells. Cardiovascular risk-associated allele frequencies for 15 genes in healthy elderly French and Chinese. The findings suggest the need of health education campaigns in general population as well of safety devices for some domestic harmful products.

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Among differential cDNA fragments two unkown sequences were found and their complete gene and gene function remained to be investigated. The examined subjects were 82 males and 308 females aged 30-69 years.

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Pharmacokinetic-pharmacodynamic modelling of intravenous and oral topiramate and its effect on phonemic fluency in adult healthy volunteers. Associations between physical activity and the neighbourhood social environment: baseline results from the HABITAT multilevel study. Broad-host-range plasmid cloning vectors for gram-negative bacteria.

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An evidence-based model for assessing risk in child sexual abuse cases is proposed. Epidural hematoma is a rare but serious neurological complication of neuraxial anesthesia. Psychological interventions may be targeted toward those whose child has had ongoing illness before extracorporeal membrane oxygenation. Preparation and efficacy of Newcastle disease virus DNA vaccine encapsulated in PLGA nanoparticles.

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