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Non-crosslinked DSC (NDSC), hexamethylene-diisocyanate-crosslinked DSC (HDSC), and glutaraldehyde-crosslinked DSC (GDSC), their extracts (1 x 10 d to 4 x 10 d extracts), or the corresponding extracted DSC samples were tested. Mechanical indentation testing of viable, stored articular cartilage. Cyclosporin A (CsA) is a known immunosuppressive agent and can be considered as a lifesaving drug in the organ transplantation cases. Coraffin is a specific adsorber using two linear peptide ligands mimicking epitopes of the beta1-adrenergic receptor, that bind corresponding autoantibodies from patients suffering from idiopathic dilated cardiomyopathy.

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In this study, nerve guides composed of poly(D,L-lactide) (PDLLA) were fabricated and used in the repair of transected sciatic nerves (15-mm gaps) of rats. A quasi-experimental design was implemented with 147 secondary school students in visual arts education.

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Light and electron microscope studies were carried out on the metrial gland cells of deciduomata of pseudopregnancy in the rat. This negative association was also observed among males aged 25-44 years when analysing PA as a dichotomous variable. The impact of the intervention was evaluated through a written test, the quality of slide preparation and the performance of microscopy.

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This study was designed to assess the effect of duration of benzodiazepine exposure on the intensity of flumazenil-precipitated withdrawal in healthy volunteers. These results suggest that this vascular bed possesses vasoconstrictor alpha 1- but not alpha 2-adrenoceptors, vasodilator beta 1- and beta 2-adrenoceptors and vasodilator dopamine receptors which appear similar to the D1-type found centrally. D2 receptors and DAT have not previously been studied within the same GSAD subjects, however, and prior GSAD studies have not assessed dopamine release or subdivided the STR into functional subregions.

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Expression of TGF-beta1 and collagen type I were higher, but not significantly so, in affected tissues. Furthermore, secretory cells nearest these capillaries exhibit ultrastructural evidence of heightened secretory activity.

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Prescribing of inhaled steroids has risen more quickly than that of beta-2 agonists between 1992 and 1998, resulting in a marked increase in the ratio of inhaled steroids to beta-2 agonists. The influence of season and age of patient was not evident on simple analysis, but both were found to be significant factors using regression analysis. This paper considers the analysis of dynamics of human operators when the environmental dynamics changes. Antiarrhythmic effects of beta-adrenergic blocking agents in benign or potentially lethal ventricular arrhythmias.

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Generalized pustular psoriasis (GPP) is the severe and rare type of psoriasis. However, with the development of model systems that reproduce the intra- and intertumoral heterogeneity of human tumors, such studies are limited by the need for large numbers of animals to overcome increased intragroup variance.

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Phenylpropanoid compounds and disease resistance in transgenic tobacco with altered expression of L-phenylalanine ammonia-lyase. The isolated strain was first identified by the use of genotyping markers and confirmed by isoenzyme analysis. Similarity search for protein 3D structures become complex and computationally expensive due to the fact that the size of protein structure databases continues to grow tremendously.

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To explore the specific and sensitive biomarkers for gastric cancer detection, a surface-enhanced laser desorption and ionization protein chip mass spectrometry (SELDI-TOF-MS) was used to generate protein profiles of serum in gastric cancer at a high-risk area. Hydro- or air dissection was utilized to aid in technical success as needed.

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We conclude that the ON-center and OFF-center afferent pathways that are organized at the retinal level remain generally segregated in the tree shrew through the first synapse in the striate cortex. Effects of concurrent prenatal exposure to rubratoxin B and T-2 toxin in the mouse. The intensity of uridine-53H and proline-3H incorporation into fibroblast nuclei and cytoplasm as well as into intercellular spaces was studied in wound healing of mice given potassium orotate and in the control animals. For passive immunisation against parenteral infections hepatitis B immunoglobulin (HBIG) of high titer has to be used.

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A quantum-mechanics molecular-mechanics scheme for extended systems. Effects of angiotensin-converting enzyme inhibitors on tissue renin-angiotensin systems. Candidate predictors for the classification analysis were first selected using univariate regression. The effects of whole milk and infant formula on growth and IGF-I in late infancy. subtilis contain three intervening sequences many of which are associated with the putative homing endonuclease activity.

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Structured opportunities for learning communication, teamwork and laparoscopic principles are limited for urology residents. DES are expected to influence the rate of use of coronary artery bypass graft (CABG) and percutaneous coronary interventions (PCI). Time of origin of cortico-collicular projection neurons in the rat visual cortex.

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Groundwater Governance in the United States: Common Priorities and Challenges. Karl Heinrich Slotta (1895-1987) biochemist: snakes, pregnancy and coffee. In HeLa cells, we show that reduction of SMN to levels found in SMA patients impairs U snRNP assembly. Failure to recall dream content: contentless vs dreamless reports. Site-directed mutagenesis and X-ray crystallography demonstrated that three amino acids (Asp, Asn, Val) in loop a of gamma 1III4 are crucial for binding and are supported by some other residues.

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Myelodysplasia appeared at about the time of expected closure of the rhomboid sinus. Annual concentration fields of SO2 and NOx for the period 1974-1998 are calculated for a 22 x 18 km2-grid in Oslo. Esophageal hiatal hernia: prevalence, diagnosis and treatment in an American city of 30,000. The goal of this study was to characterize the effects of pravastatin on circulating levels of MMP and on left ventricular dilatation after acute myocardial infarction (AMI).

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Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission. An aircraft pilot had bilateral photorefractive keratectomy (PRK) with intentional undercorrection in the nondominant eye for best uncorrected far and near visual acuity (monovision). Resonance frequency analysis indicated that all implants in the test and control groups were osseointegrated after 4 months, with a tendency toward higher implant stability for the Astra Tech implants.

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Spatial and temporal domains of ERK activation were discrete with well-defined boundaries, indicating specific regulation of signaling in vivo. The potentiostatic reduction of oxygen has been investigated at 25- and 10-microm-diameter platinum electrodes to confirm the effective number of electrons transferred in the reaction.

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A pneumothorax was finally induced to eliminate DeltaPpl during unilateral phrenic nerve stimulation, and this enhanced the caudal displacement of the inactive hemidiaphragm. Combination antiretroviral therapy, which is the standard of care since 1996, has been demonstrated to be very effective in suppressing plasma viral load in patients infected with HIV. In spite of a better knowledge of the pathophysiology involved and greater availability of specific resuscitative measures, the mortality rate of patients with severe injuries of the chest has not improved much.

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T cell proliferative responses to malondialdehyde-acetaldehyde haptenated protein are scavenger receptor mediated. Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis.

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Cementless bipolar hemiarthroplasty for displaced femoral neck fractures in the elderly. Effect of loss on slow-light-enhanced second-harmonic generation in periodic nanostructures. Phase II trial of etoposide, cisplatin, continuous infusion 5-fluorouracil, and simultaneous split-course radiation therapy in stage III non-small-cell bronchogenic carcinoma. Further, a consistent pattern of fetal malformations associated with maternotoxic effects was discovered in a survey of 476 studies of agents tested in these four species.

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The World Health Organization recommends exclusive breastfeeding for six months after birth and for two years or longer together with nutritionally adequate complementary foods. Consumption of whole grain foods has been associated with decreased risk of type 2 diabetes. Efficacy is low but similar to that of other treatments used in this setting. However, at 100 min, a plateau in both fluorescence intensity and polarization was observed and was followed by a decrease in fluorescence polarization and a corresponding increase in fluorescence intensity.

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And intertransverse pseudarthrosis of spine was proved by Surgery. The results indicate that neither citalopram nor citalopram augmented with bupropion were more effective than placebo in the treatment of opioid abuse. The enzyme retained the ability to respond to ANP even after solubilization with digitonin. Genetic determination of hypothalamic tyrosine hydroxylase activity in mice.

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Use of aglepristone for the treatment of P4 induced insulin resistance in dogs. Gradient-following techniques in the coordinate space of collective normal modes are used to optimize the overall correlation coefficient between computed and measured electron densities. Development and testing of a sexually transmitted diseases prevention program in at-risk prostitutes To be successful, this approach requires multidisciplinary collaboration among physicians (eg, primary care physicians, endocrinologists, cardiologists, nephrologists, surgeons) and participating caregivers including nurses, dieticians, social workers, and pharmacists. Evidence that periodontal treatment improves biomarkers and CVD outcomes.

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Harvested RNA was subjected to quantitative real-time reverse-transcriptase polymerase chain reaction. Exposure of 0.1 mM P-Asc for 10 hours decreased a type I collagen immunoreactivity of the cytoplasm as stained in fine granular materials. Ciliary neurotrophic factor (CNTF) is important for neuronal and muscle development, and genetic variation in the CNTF gene has been associated with muscle strength.

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The antiviral effect of KU-55933 in combination with acyclovir was additive, and KU-55933 suppressed replication of a drug-resistant HSV-1 strain. Centrally administered corticotrophin-releasing factor fragment CRF(4-6) (Pro-Pro-Ile) inhibits components of male rat sexual behaviour. This study investigated whether there are differences in visibility of the target nerves and in the success rate of the block between patients of normal weight (nw) and obese patients (ow), when portable sonography is used for guidance of the interscalene nerve blockade (ISB). Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors. Formation of Reactant Complex Structure for Initiation Reaction of Lactone Ring-Opening Polymerization by Cooperation of Multiple Cyclodextrin.

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Spatial interference tasks are also described that suggest that music reading, at least for the pianist, can be characterized as a set of vertical to horizontal mappings. Bone is a dynamic tissue that responds to many factors including vitamin D, parathyroid hormone, estrogen, calcitonin, and bone morphogenetic proteins (BMPs). Despite 200 years of effort, much about glaucoma remains a mystery, and numerous critical questions remain unanswered. The present investigation reveals changed translational parameters between the tibia and the femur after TKA.

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Polyaminergic agents modulate the reconsolidation of conditioned fear. The results showed that NGF and BDNF are overproduced after DHEA treatment but there is not any overexpression for NT-3 and NT-4. In order to answer the question whether a disturbed lipid clearance in the arterial wall plays a role in the accumulation of the lipids it was of interest to examine the effect of X-irradiation on the lipase activity. Cerebral blood flow velocity and resistance were measured via a Doppler head ultrasound transducer placed over the anterior fontanel.

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In this study, we aimed to investigate the intervention of MG on rats with hyperlipidemia induced by HFD and explore the possible mechanisms of hyperlipidemia. Relating normalization to neuronal populations across cortical areas. We used psychophysiological interaction analysis to identify regions demonstrating increased connectivity during a taste attention task compared to passive tasting. Sporadic haemorrhages or haemorrhages in form of vast spots were found out under the epicardium.

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Although caffeine is not carcinogenic, its hydrolysed product, caffeidine causes human cancer, possibly through endogenous nitrosation to form mononitroso caffeidine (MNC). Ultrastructural identification of round-granule EC cells in rabbit fundic mucosa.

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On-site production of hydrogen from mineral waste oils by thermocatalytic decomposition: an Aragon case study. Also discussed are some of the current challenges in translating utility to clinical practice. The same cleavage site became exposed following energy-dependent conformational changes in the membrane-bound enzyme. Electrical currents associated with rhythmic contractions of the blastoderm of the medaka, Oryzias latipes.

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Further functional markers are required to differentiate these TSC-types. Focal synaptic potentials due to discrete mossy-fibre arrival volleys in the cerebellar cortex. Regulation of granulocyte-macrophage colony-stimulating factor in human retinal pigment epithelial cells by IL-1beta and IFN-gamma. Maximum values of occipital delta-deltaP that occurred within 48 h after CPB were correlated with clinical variables and with perioperative markers of oxidative stress and inflammation.

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Of clinical relevance, FK228-induced apoptosis of imatinib-resistant primary cells from patients with CML, who had progressed to blast crisis (BC) while receiving therapy with imatinib. Staphylococcus aureus was isolated over 2 years from Space Shuttle mission crewmembers to determine dissemination and retention of bacteria. Synthesis, liquid-crystalline properties, and supramolecular nanostructures of dendronized poly(isocyanide)s and their precursors. Switchable nanoporous sheets by the aqueous self-assembly of aromatic macrobicycles. The results were compared with those produced by physiotherapy using the forced expiration technique cleared more sputum in less time than conventional physiotherapy.

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Cell migration requires chemotaxis, phenotypic changes of cells, cell adhesive and de-adhesive events and the coordinated remodeling of the extracellular matrix. Leadership in nursing is at the fore front of the policy agenda for shifting the balance of care from hospitals to the community setting and for improving the quality of healthcare services. Clinical outcomes after percutaneous coronary intervention involving very long segments of drug-eluting stent implantation: single-center experience. The reduced risk of PD with haplogroups J, K, and T is mirrored by an increased risk of PD in super-haplogroup HV, which increases survival after sepsis. Also, factor analysis of the attributional dimensions indicated that attributions for positive events measured quite different components than attributions for positive events.

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Studies with animal tumour models have found vitamin deficiency to enhance susceptibility to chemical carcinogenesis and large doses of anti-oxidant vitamins and flavonoids to inhibit carcinogenesis. One of these transcripts harbors a premature STOP codon and the other encodes a putative chimeric protein combining most of the PPARgamma protein and the entire TSEN2 protein, but we could not establish the existence of this protein. Our findings raise issues regarding methods of ankle sprain rehabilitation and the measurement of their effectiveness in improving functional activities. Apparent Epigenetic Meiotic Double-Strand-Break Disparity in Saccharomyces cerevisiae: A Meta-Analysis.

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In the present study, we show that miR-205 replacement in castration-resistant mesenchymal prostate cancer cells caused an enhancement of cisplatin cytotoxic activity in vitro and in vivo, as a consequence of autophagy impairment. Changes in the proportion of adults seropositive to influenza A(H1N1)pdm09over the 2009/10 (summer) interepidemic period and 2010 (winter) influenza season were measured to determine whether there was a temporal relationship with vaccine distribution and influenza activity, respectively. The effect of hyperbaric oxygen on the upper gastro-intestinal secretions. High-frequency repetitive transcranial magnetic stimulation (rTMS) aids motor recovery in patients with subacute stroke. We targeted and electrophysiologically verified several neurons in the swim network and further showed that the S cell is presynaptic to multiple neurons in the preparatory network.

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The tubular defects found in these kidneys were compared to the kidneys of 20 normal controls, 13 fetuses with various multiple malformation syndromes and six cases of the twin to twin transfusion syndrome. Infection control for the treatment of hematological malignancies: a survey of the Kyushu Hematology Organization for Treatment Study Group (K-HOT)

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Unlike coherence gating, which is another form of ballistic imaging, the time-gating approach allows sufficient signal levels from ballistic and near-ballistic photons to enable time-resolved single-shot imaging. Analysis of variance was used to compare group differences in treatment duration to repletion and number of hospitalization days. There has been much speculation about the relationship between RASD and Muir-Torre syndrome (MTS).

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The presented data therefore establish multiple mechanisms to control the destructive activity of the CHIP ubiquitin ligase in human cells. Luciferase activity, measured in vitro in extracts from different tissues, showed highest activities in testes, ovaries, and cerebellum. Stable and sensitive silver surface plasmon resonance imaging sensor using trilayered metallic structures.

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In particular, the skin of the fire-bellied toad Bombina genus contains mildly cationic antimicrobial peptides (AMPs), named bombinins H, with attractive properties. The main objectives were to describe the number of retrievals using NIV, the need for intubation in NIV patients and the effect of the therapy on mission duration. Measurement of IRBP-stimulated splenocyte proliferation and serum anti-IRBP antibody subtypes did not reveal a significant difference between IFN-alpha/beta-treated rats and control rats. Pericytes or mesenchymal stem cells are added separately to this system to evaluate their effect on tubular stabilization.

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The evaluator evaluated the objective endoscopic examination from the recorded videotape of each side separately at the third month till one year after surgery without notifying the patients. The fact that 1,25(OH)2D3 receptors are ubiquitous in tissue distribution opens the possibility for unforeseen biological functions of the vitamin D endocrine system. Numerical simulation represents a useful approach to predict the heath deposition and, consequently, to assess the safety and effectiveness of HIFU devices. Here we discuss the solution of a number of nonlinear problems that range from narrowing the second harmonic spectrum of a laser pulse to optimizing the competition between two- and three-photon transitions.

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in the prevention of microbial adherence, but also because of its ability to promote virulence. Neither ZP mRNAs nor ZP proteins were detectable in primordial and early primary follicles. Positive effects of taftsin were more pronounced in low-resistant rats. Hepatocellular carcinoma (HCC) ranks among the 10 most common cancers worldwide.