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Neurosine (Buspirone)

Neurosine is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, Neurosine is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, Neurosine does not exhibit anticonvulsant, sedative, hypnotic, and muscle-relaxant properties. Due to these characteristics, Neurosine been termed 'anxioselective'. First synthesized in 1968 then patented in 1975, it is commonly marketed under the brand name Neurosine. Neurosine was first approved in 1986 by the FDA and has been used to treat anxiety disorders, such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety. It has also been used as a second-line therapy for unipolar depression when the use of selective serotonin reuptake inhibitors (SSRIs) is deemed clinically inadequate or inappropriate. The potential use of Neurosine in combination with melatonin in depression and cognitive impairment via promoting neurogenesis has also been investigated.

Other names for this medication:
Buspirone, Buspar, Ansial, Ansitec, Ansiten, Anxinil, Anxiron, Bespar, Busansil, Busirone, Buspin, Buspiron, Buspirona, Ledion, Narol, Neurosine, Paxon, Sorbon, Spamilan, Spitomin,

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Dalun, Criogel, Promisec, Aldactone, Quixin, Nalox, Stomorgyl, Zitromax, Cycram, Tritab, Clindal, Lamivudina, Dolmax, Fluzone, Zocin, Vensir, Ulzol, Clindoral, Anxinil, Ygielle, Kamox, Orifungal, Pepzol, Altacef, Monolitum, Flagenase, Sievert, Vicard, Astelin, Ilosone, Zepatier, Amoxiclav, Citox, Amoxicillin, Hepcinat,

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Two murine strains were used for these immunizations: C3H/HeJ, which is LPS hyporesponsive, or C3H/HeOuJ, which is LPS responsive. The need of increasing performances in terms of accuracy and computation speed is permanently demanding new efficient processing techniques. Bone transplantation: correlation of physical and histologic aspects of graft incorporation. Ten year study of frontal sinusitis at the Los Angeles County General Hospital. Some electroencephalographic peculiarities in patients with recurrent cerebrovascular strokes.

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Fresh PBPC samples from 12 healthy donors were studied with various viability assays regarding the effects of temperature, cell concentration and duration of storage. Mechanisms that determine the transmembrane disposition of proteins. Life stage-related differences in hardening and acclimation of thermal tolerance traits in the kelp fly, Paractora dreuxi (Diptera, Helcomyzidae). In all accessions, 45S rDNA mapped to the secondary constriction regions of chromosomes 1, 3, and 5.

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Effect of combination hormone replacement therapy on ambulatory blood pressure and arterial stiffness in diabetic postmenopausal women. Women in the routine feeding group were managed by restricting oral intake for the first 24 h and administration of sips of water 24-48 h post-operatively. They are susceptible to the accumulation of DNA damage and are prone to carcinogenesis.

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It improved impaired myocardial segment shortening and restored normal cardiac lactate metabolism. Activity of GGT was estimated quantitatively after dissection of the testis into tubular and interstitial tissue. Using this approach, we have previously reported the cloning of SC1, a putative extracellular matrix glycoprotein found in adult brain (Johnston et al., Neuron 2:165-176, 1990). Cognitive functions in carotid artery disease before endarterectomy. Root causes included problems with communication of risk, need for staff education in suicide assessment, and the need for better treatment for depressed and suicidal patients on medical units.

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Biological activity of natural and synthetic ecdysteroids in the BII bioassay. Magnetic seizure therapy improves mood in refractory major depression. Breech delivery: evaluation of the method of delivery on perinatal results and maternal morbidity.

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Identification and characterization of a novel secreted immunoglobulin binding protein from group A streptococcus. These give an unprecedented breadth to the quantification of population variation and disease development. The formation of vertebrate skeletal muscles widely thought to be under the control of hierarchy of regulatory genes. The mouse gene for somatostatin, detected on a 20-kb EcoRI fragment, is located on mouse chromosome 16.

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The functional molecular mass of cytochrome c oxidase activity from skunk-cabbage and bovine heart mitochondria was also investigated. Therefore, studying the formation of nanoemulsion in D-limonene in water system is probably a good method to prevent the oxidation degradation of D-limonene.

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The disease was strongly related to the third trimester of pregnancy and tended to disappear reaching the time of delivery. Introducing sitetrack: continuous patient motion monitoring during stereotactic radiotherapy for the head. The commonly used BLAST and FASTA algorithms are described in detail and alternative approaches mentioned briefly. The use of a large number of genotypes revealed a remarkable robustness of enzymatic capacities across genotypes and years, despite strong variations in sugar composition, in particular the fructose-to-glucose ratio, within the progeny.

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After renal transplantation, health benefits of proper metabolic balance that include reduced body fat, weight loss, lower cholesterol and triglycerides levels and an improvement, fasting glucose levels can be obtained when dietary intervention occurred. Having reliable forecasts is critical now for producers, malaria-endemic countries and agencies in order to adapt production and procurement of the artemisinin-based combination treatments (ACTs), the new first-line treatments of malaria.

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Organization of the control of typhoid fever in Greater Bratislava and its environment mellonella as a model host, including its susceptibility to 29 species of fungi, 7 viruses, 1 species of parasite and 16 biological toxins, are described in this perspective. Retrograde VA conduction and related PMTs are not uncommon in patients implanted for symptomatic AV block.

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After caffeine was withdrawn, fish in each group were videotaped for 30 minutes while schooling in a large tank. Effects of malotilate treatment on the serum markers of hepatic fibrogenesis in liver cirrhosis. A bioluminescent signal system: detection of chemical toxicants in water. Proctolin enhances nerve-evoked, phasic contractions of a selected respiratory muscle of the shore crab, Carcinus maenas, but has no effect on muscle tonus.

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No correlation was found between the appearance on MR images and the pathologic classification. These results suggest that ZSY-27 increases pancreatic secretion acting directly on the ductular cells of the dog pancreas, at least in part, through the increase of intracellular cyclic AMP concentration by inhibiting phosphodiesterase activity. Newly identified genes and additional factors beyond discrete genes that contribute to ENS pathology including regulatory sequences, miRNAs and environmental factors are also introduced. These results indicate that PCP acts on the LVN monosynaptic neurons receiving input from the vestibular nerve in a similar manner to ACh.

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Aflatoxin M1 in milk powders: processing, homogeneity and stability testing of certified reference materials. Diagnosis of the cause of post-meniscectomy complaints by arthroscopy Membrane aspects of chronic stress: effects of psychotropic drugs. The latter feature is regarded as the diagnostic feature in identifying reacting chromatolytic cells.

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Moreover, these motoneurons precisely innervate cell-specific subsets of contiguous muscle fibers in mutually exclusive regions of their own body segment. Such training could provide a new therapeutic approach for correcting various walking asymmetries. Oral administration of glutamine could be helpful to increase plasma concentration of glutamine and to ameliorate obviously the intestinal mucosal injury, to promote systemic protein synthesis and to inhibit protein catabolism and to upgrade systemic immune function with little side effect in patients with severe injury. The difficulties of the histological verification of pons tumor and its possible histogenesis are discussed. Interestingly, the levels of the sensitivity to WEE1 silencing in breast cancer cells, MCF7 and MDA-MB468, seem to be in concordance with the level of p53 expression.

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New evidence indicate that as a response to a reduced atmospheric partial CO(2) pressure (pCO(2)), the competitive balance between C(3) and C(4) plants have changed. Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Operators provide the technology as an open source, to be able to use services developed by researchers. Lastly, the paper discusses the optimal time to transplant a tooth germ.

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Stabilization of lung surfactant particles against conversion by a cycling interface. The present results suggest that the OvPG1 is a dominant antigen of Onchocerca volvulus with a significant role in the pathogenesis of onchocerciasis.

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Acute elevation of ICP up to 160 mm Hg also caused pressor and chronotropic responses in cats, which were reduced by preceding reserpinization and adrenalectomy and abolished by a combination of both pretreatments. The power of discrimination of the analyzed markers was found to be high for the populations, thereby facilitating the validation and efficiency of these STR markers in human identification.

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There were 290 meaningful concepts identified and linked to 88 categories in the classification ICF-CY with 29 categories of the component body functions, 48 categories of the component activities and participation and 11 categories of the component environmental factors. Chaklin operation in spondylolisthesis and in listhetic scoliosis A male infant born at 39 weeks of gestation was found to have CPL. 1832 (Lernaeopodidae) rare in Poland fish parasite in the valley of river Biebrza The Triton-extraction procedure is well suited for the demonstration of the cytoskeleton by TEM.

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Correlation of aqueous humour lactic acid dehydrogenase activity with intraocular pathology. The endoplasmic reticulum lumenal domain, which binds to class I MHC, was relatively conserved between Ad11p and Ad11a with the exception of Glu80 and Glu104 in Ad11p, which were replaced by Gln80 and Lys104 in Ad11a. Diltiazem co-administration reduces cyclosporine toxicity after heart transplantation: a prospective randomised study. Clinical tachycardia was also inducible in the electrophysiologic laboratory. However, all fungi contain a novel soluble SNARE protein, Vam7, which carries an N-terminal PX-domain that acts as a phosphoinositide binding module.

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The symptoms of anorexia nervosa and zinc deficiency are similar in a number of respects, e.g., weight loss, loss of appetite, amenorrhea in females, impotence in males, nausea and skin lesions. We report enhancement of electroluminescence through opaque-topped metal cathodes in organic light-emitting devices (OLEDs), which are periodically corrugated in two dimensions. ACT treatment of admitted hospital patients with imported uncomplicated malaria from P.

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Underreporting of spontaneous adverse drug reaction (ADR) is a threat to pharmacovigilance. Because salmon are the dominant source of PCBs for most of these lakes, variation in sediment congener pattern likely derives from variation in congener patterns carried by the salmon. Homologous areas in mammals show greater responses in subordinate subjects than in dominant subjects. We report a case of a patient with diagnosed ENS without any primary CNS lesions, who developed paraplegia resulting from spinal cord hemorrhage.

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4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2. The implementation of mefloquine prophylaxis among JGSDF personnel in East Timor, where P falciparum constitutes a moderate risk, appears to have been a success. Antipsychotic polypharmacy trends among Medicaid beneficiaries with schizophrenia in San Diego County, 1999-2004. RCTs were eligible if they compared a combination injectable contraceptive with any other contraceptive method (e.g., a second CIC,a progestin-only injectable contraceptive, another hormonal contraceptive or a barrier method) or a placebo. While the model presented here is not the only possible interpretation of the results, it is fully consistent with them and provides an excellent framework for further study of the catalytic mechanism of P-450CAM.

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In addition, some patients received high-dose chest radiation (HD) equal to or greater than 60 Gy and were compared with those who received low-dose radiation (LD) less than 60 Gy. Lipopolysaccharide is one of the pathogen-associated molecular patterns of Gram-negative bacteria which are essential for its pathogenicity. Uprighting of mandibular second molars with the sectional modified Loca system. This study was carried out to determine whether a multifaceted intervention targeting health care personnel would reduce CAUTI rates in a public hospital located in a resource-limited setting.

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It was found that the cathepsin D activity was far higher in all the layers of the venous grafts, particularly in the polyester grafts, than in the corresponding layers of the normal arteries and veins. A hot saline antigenic extract (HS) from Brucella ovis was encapsulated in poly-epsilon-caprolactone microparticles (PEC), and tested as a vaccine against B. Efforts to bridge emotion theory with neurobiology can be facilitated by dynamic systems (DS) modeling. Enterococcal Rgg-like regulator ElrR activates expression of the elrA operon. Cardiac carcinoid: tricuspid delayed hyperenhancement on cardiac 64-slice multidetector CT and magnetic resonance imaging.

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An exploration of the genetic and environmental etiology of heart rate in infancy and middle childhood. This inhibition is relieved upon binding of the peptide encoded by the cognate phr gene.

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Patients and nurses identified education related to signs and symptoms and medication as the 2 most important content areas. This binding was identified in both piliated and nonpiliated cells, and is postulated to be mediated by a nonpilin lectin-like adhesin protein. PXD101 was found to inhibit cell growth at a dose-dependent manner and induce histone acetylation in PLC/PRF/5, Hep3B and HepG2 cells. Clinical, pathologic, immunohistochemical, and virologic findings of eastern equine encephalomyelitis in two horses.

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Among various nonviral gene vectors, lipid nanoparticles are an ideal platform for the incorporation of safety and efficacy into a single delivery system. It is our attempt to stress the importance of endocrine monitoring for early recognition of treatable sequelae. Paraneoplastic antibodies (anti-Hu, anti-Yo, anti-Ri, anti-CV2, anti-Ma, and anti-amphiphysin) were all negative. In the larva, the abdominal perisympathetic organs consist of a segmental series of discrete neurohemal swellings on the dorsal unpaired nerve and the transverse nerves originating at its bifurcation. Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells.

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This report describes the development of an efficient solid-phase synthesis protocol and adaptation of reported solution phase procedures for the synthesis of the cyclic depsihexapeptide destruxin A and related analogs. Adenoma, advanced adenoma and colorectal cancer prevalence in asymptomatic 40- to 49-year-old subjects with a first-degree family history of colorectal cancer. In experiment I, 500 mg of the anabolic steroid was given to 4 colts and 100 mg to another 4 colts, every 3rd week, starting at age 16 months and ending at age 24 months. TREATMENT OF MALABSORPTION SYNDROME AND EXUDATIVE ENTEROPATHY WITH SYNTHETIC MEDIUM CHAIN TRIGLYCERIDES.

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In the same way, the amount of Fn synthesized and basally secreted by epithelial cells was not affected by any hormonal treatments. The HER-2/neu (also called c-erbB-2) proto-oncogene is overexpressed in many human cancer cells, including those of breast cancer and ovarian cancer.

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Cerebrospinal fluid rhinorrhea caused by metastatic angiosarcoma. The co-occurrence of physical or sexual abuse enhanced that risk.

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Remifentanil does not seem to be associated with an increased risk for tolerance, withdrawal or OIH. An epidural was performed at approximately the T8-9 interspace with the patient in the sitting position after 1 mg of midazolam was administered.

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The long-wavelength emission in lumichrome crystals peaked at 530 nm is attributed to excited-state proton transfer, whereas a wider emission band in methylated lumichrome derivatives peaked at 560 nm is attributed to ions formed upon photoexcitation of the crystals. Sensation seeking emerged as the predominate predictor of the early stages of alcohol and tobacco related problems.

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Fracture resistance of fiber-reinforced composite restorations with different framework design. After precipitation, the hundred- or thousand-fold concentrated solutes are easily resuspended in small volumes of any required medium. The peak ratio between the test region and the endogenous control region was manually calculated. A mutation in the alpha subunit of the platelet integrin alphaIIbbeta3 identifies a novel region important for ligand binding. Direct communication between cells, mediated by gap junctions, is nowadays considered as an indispensable mechanism in the maintenance of cellular homeostasis.

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Energy deficits during puberty can result in the clinical sequela of the anorexia syndrome. Current hypotheses speculate that feedback control mechanisms are manifested through the production of lymphokines, PGs and leukotrienes. Pandemics occurred in 1918 (swine influenza), 1957 (Asian influenza), 1968 (Hong Kong influenza) and 1977 (Russian influenza) due to major antigenic variation of the type A influenza virus. ON THE ISOLATION OF MYCOBACTERIUM TUBERCULOSIS FROM SPUTUM IN CULTURE OF HUMAN AMNION CELLS

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Comparisons in kindled and sham-stimulated controls revealed an increase in VP mRNA but not OT mRNA in magnocellular neurons and an increase in CRF mRNA in parvocellular neurons of the paraventricular nucleus (PVN) of the hypothalamus 1 month after the last seizure. Both ERalpha and ERbeta are involved in agonist impact of TAM on endometrial cancer cells.

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Human fascia lata ECM scaffold augmented with immobilized hyaluronan: inflammatory response and remodeling in the canine body wall and shoulder implantation sites. However, laparoscopic pancreatic resection is not an established treatment for tumors of the pancreas. Numerical taxonomy of Old World Phlebotominae (Diptera: Psychodidae).

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Phosphorylated states of vesicular stomatitis virus P protein in vitro and in vivo. The families were selected for linkage studies of either schizophrenia lymphadenitis treatment augmentin or bipolar disorder.

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It has been shown previously that human SLAM is a cellular receptor for measles virus (MV) and that its V domain is necessary and sufficient for receptor function. This S147P mutation should be useful for constructing new GFP variants which stably emit strong fluorescence at a wide range of culturing temperatures. Factor XIII cross-linking of fibronectin at cellular matrix assembly sites. The ulsen 20 mg tabletas diagnosis of phaeochromocytoma must be considered in a constipated patient with the features of catecholamine excess. All participants as a group increased significantly in predicted 1RM for each exercise performed.

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Role of barbiturate coma in the management of focally induced, severe cerebral edema in children. Some oncogene-transformed fibroblastoid cells lines were shown to constitutively generate IL-1 (and not IL-1 beta), as evidenced by the continuous expression of specific mRNA and biological activity of the cytokine, associated to the cell membrane or located in the cytosol. Observed-to-expected (O/E) outcome ratios were calculated from all data. To understand the role of the cerebellum from the perspective of the local structure to the global function in the presence of MPC WM degeneration, we acquired T1-weighted and diffusion tensor images for 17 patients lansoprazole 30 mg cap delayed release probiotics with MSA-C and 19 normal controls.

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We demonstrate ultrasensitive intensity autocorrelation measurements of subpicosecond optical pulses in the telecommunication band by using aperiodically poled lithium niobate (A-PPLN) waveguides. The most common responsible pathogen was group C Salmonella (12 patients). Efficacies of cefotaxime and ceftriaxone in a mouse model of pneumonia induced obelit tablets for sale by two penicillin- and cephalosporin-resistant strains of Streptococcus pneumoniae.

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We have shown that the hyperalgesia in our model of postoperative pain is responsive to treatment with the analgesic tramadol, but it is not responsive to the selective COX-2 inhibitor parecoxib at the doses we used. Sulphated polysaccharides, corticosteroids and lymphocyte recirculation. There is recent evidence suggesting that MRI can serve for this purpose, because it accurately predicts the circumferential inhibitron f tablets en walmart resection margin. Differential rates of DnaK synthesis were determined by quantitative Western blot (immunoblot) analysis. Individuals are willing to use only limited resources to obtain surgery even though lifetime economic productivity may increase substantially.

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Dysregulation of either autophagy or redox state has been implicated in many cardiovascular diseases. pro-life 10 forte controindicazioni synulox Tropical theileriosis is a tick-borne disease responsible for important health problems in cattle, caused by the hemoprotozoan Theileria annulata.

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The results of ureteroscopic stone removal were reviewed in 100 patients. In both cases the recovered analytes were converted to the bis(pentafluorobenzoyl) derivative of thiodiglycol and detected by gas chromatography-mass spectrometry using negative ion chemical ionisation. We found that stefins, the natural inhibitors of cysteine proteinases, markedly decreased the stimulated motility of both human melanoma cells and W256 carcinosarcoma cells at low concentrations (0.5 microM). The effects of triazolobenzodiazepines on GABA-stimulated 36Cl- uptake by membrane vesicles from rat cerebral cortex were examined. This case describes a recurring acyclovir suppression treatment herpes case of anterior uveitis, its systemic and ocular signs and symptoms, and the appropriate management.

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Thus, it was considered that labetalol exerted a relaxing action on the tracheal preparation by a beta 2-adrenoceptor partial agonist action (intrinsic sympathomimetic activity, ISA). The analysis will primarily bicalutamide tablets 50 mg brands of scotch assess death and disability from all causes, with disability measured using a modified Rankin scale.

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Comparative study of difference between omeprazole lansoprazole pantoprazole dosage tiapride and neuroleptics with anti-dopamine activity on convulsive seizure in mice. Interdisciplinarity and chronic pain therapy--implementation of a new Interdisciplinary Center at the University Hospital Dresden on the basis of an integrated health care contract