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In contrast to HSV-tk gene, T cells infected HSV-sr39tk were more sensitive not only to GCV but also to ACV. Albinism, stigma, subjectivity and global-local discourses in Tanzania. Collagen morphology is not associated with the Ala549Pro polymorphism of the COL1A2 gene. Spinal circuits can accommodate interaction torques during multijoint limb movements. The findings suggested that a inflammation like periarteritis nodosa had occurred at the spermatic cord and subsequently developed into fatty degeneration in the surroundings.

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The anatomical substrate and exact meaning of the MR signal of pathological tissue still remains to be specified. With ultrasonic tracking, the location of a medical device is determined by ultrasonic communication between the ultrasound imaging probe and a transducer integrated into the medical device.

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EEGs were recorded through intracranial electrodes and were reviewed and staged blindly. With the long-term goal of complete understanding of a cell, we have over the past decade created a variety of clone and mutant sets for functional genomics studies of Escherichia coli K-12. Further biological, serological and biochemical characterization of North American, European and Southeast Asian strains of bovine herpesvirus 1 compared with other alphaherpesvirinae members.

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Clinical Prognostic Score for Predicting Disease Remission with Differentiated Thyroid Cancers. We compared balloon expulsion, defecography, colonic transit times, anal manometry, and electromyography in 21 patients with severe constipation.

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Disseminated intravascular coagulation associated with group A streptococcal infection in pregnancy. Detection of asymptomatic peripheral arterial disease increases the risk of vascular morbibity and mortality. The optimised MAE method provides extracts that can be analysed quantitatively using 1H-NMR without any preliminary clean-up or derivatisation steps. The goal of these studies was to determine the rate of release of Pt as a function of pH, the antitumor activity, and plasma and tumor pharmacokinetics of AP5346 in preclinical models. This has been demonstrated by using inhibitors for polyamine biosynthesis (such as alpha-difluoromethylornithine) or adding polyamines to cultured cells.

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This Tutorial Review shows how Raman spectroscopic and microscopic techniques are utilised for non-destructive characterisation of archaeological artefacts and provide novel information for art historians and hints at the use of ancient technologies for the production and treatment of materials and skeletal remains. Anterior mediastinal masses with calcifications on CT in children with histiocytosis-X (Langerhans cell histiocytosis). Sustained negative chronotropic effects were recorded at the highest dose only and were best related to the amount of clentiazem detectable in the myocardium, suggesting that myocardial clentiazem retention is a major factor governing its depressant cardiac impact. Treatment of carcinoma of the penis by iridium 192 wire implant.

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Considering the poor sensitivity of FLT, and the comparable cost and time of obtaining a CDTA at our institution, we conclude that FLT is not a good screening test for CDAD. These results indicate that, although tact and mand functions are different, conditions can be created to facilitate transfer from the former to the latter. Hazards of the intra-arterial oxygen therapy and their prevention Hemispheric differences in a negative brain potential associated with selectively attending the location and type of stimulation were investigated. The family context, family history and perceptions about family duties and responsibilities were important motivators for communication about risk, genetic testing and colonoscopy and influenced participation in genetic testing and screening programmes.

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The various scales correlated differently with various personality traits. Filopodia act as phagocytic tentacles and pull with discrete steps and a load-dependent velocity. Photodynamics of Schiff base salicylideneaniline: trajectory surface-hopping simulations. Developmental regulation of calmodulin gene expression in rat brain and skeletal muscle.

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Three populations of brown trout (Salmo trutta) exposed to different metal levels in their natural environments, were studied with respect to antioxidants metallothionein (MT), superoxide dismutase (SOD) and catalase (CAT) as well as for corresponding mRNA levels. The role of different variables in the development of tardive dyskinesia was examined among patients in two different diagnostic categories. The maximum responses (Emax) were significantly increased during pregnancy and hormone supplementation. The following review explores the epidemiological evidence for the relationship between depression and CHD, examines the biological, behavioral and social mechanisms that may account for this relationship, and considers the findings of the psychological and pharmacological intervention trials seeking to improve outcomes for depressed cardiac patients.

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Splenomegaly is usually a result of torsion of the pedicle and splenic sequestration. Our findings suggest the presence of neurologic sequelae of soccer play, even in college-level players. However, the immediate downstream targets of Pelle have not been identified.

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No differences in the expression of several components of the basal membrane zone (heparan sulphate proteoglycan, laminin, tenascin) were noted between hypertrophic and non-hypertrophic scars. Partial neuroprotective effect of pretreatment with tanshinone IIA on neonatal hypoxia-ischemia brain damage.

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The diphtheria-pertussis-tetanus (DPT) vaccine prevents the symptoms of three serious and often fatal diseases due to the exotoxins produced by Corynebacterium diphteriae, Bordetella pertussis and Clostridium tetani. Several complementary therapy modalities can be helpful in improving the overall care of patients with lung cancer. Conversely, reduction of endogenous L11 by siRNA increases these c-Myc activities.

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Presentation of early onset psoriasis in comparison with late onset psoriasis: a clinical study from Pakistan. The diagnosis can be ascertained by the Doppler-echocardiographic proof of a regurgitation through the aortic valve. There is substantive evidence of significant psychiatric morbidity among primary care patients, mainly in the form of anxiety and depressive disorders.

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Rapid reversal of life-threatening hypoglycaemia with a somatostatin analogue (octreotide). In vitro inhibitory effect of lercanidipine on cholesterol accumulation and matrix metalloproteinases secretion by macrophages. Treating hemocytes with Pertussis toxin, a known inhibitor of the signaling pathway initiated by the mammalian fMLP receptor, returned phagocytosis to basal levels. Two distinct kinin receptors have been described, one constitutive (subtype B2) and one inducible (subtype B1), and many physiological functions have been attributed to these receptors, including glucose homeostasis and control of vascular permeability.

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Additionally, a comparison of interspecies nodule proteomes displays that overlapping and individual mechanisms are associated with legume nodulation. Hsulf-1-positive nude mouse tumours showed better development of interstitial matrix structures, with increased blood vessel density in these tumours.

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A multivariate analysis of 9 brain indices from 83 teleost species showed a marked opposition between the non-olfactory telencephalon (and diencephalon) and the medulla oblongata (phylogenetic characters) and between the olfactory bulbs and the optic tectum (adaptive characters). Dental education in the United States has changed considerably over the last 30 years and it could be argued that not all the changes are positive. Despite increasing interest, little is known about the PAP/RegIII protein. Genetic screens based on the use of MudJ-generated lac fusions permitted the identification of novel genes regulated by the Rcs signal transduction system in Salmonella enterica serovar Typhimurium.

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Moreover, it is possible that the cell-killing and appotosis-inducing effects of HT may be mediated by the inhibition of the expression of CenpB and other centromere protein genes. Within 72 hours postsurgery, each underwent diffusion-weighted magnetic resonance imaging, a sensitive test for cerebral ischemic events. Neighborhood walkability-related attributes should be taken into account when promoting the use of existing parks or creating new parks. Old World animals, with the exception of the chimpanzee, have ample amounts of arsenite and monomethylarsonic acid methyltransferases.

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Airway epithelium alterations, including squamous cell metaplasia, characterize smokers with and without chronic obstructive pulmonary disease (COPD). Given that inequity stresses are heaviest in the uneducated and probably rural and poor groups, interventions should aim to reach this group. A questionnaire-based observational research design using the audiology occupational stress questionnaire (AOSQ) was used. Eighty-one esophageal SmCC patients were treated from 1999 to 2007 in our department, and their clinical data were retrospectively reviewed.

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ET-1 was able to enhance the IL-6 promoter activity and its stimulatory effect was inhibited by GF109203X, U0126, salicylate, dominant negative CREB and mithramycin A. This study points to the need for a national database that would allow for a more comprehensive quality-controlled data collection that would provide more meaningful evaluation of direct and indirect effects of risk variables and intervention development. Of the X-ray methods for the demonstration of disturbances of the blood supply only the angiography is of practical importance.

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The extreme lability of the chlorine ligands was apparent, as well as the reactivity of the resulting zirconium metal center as demonstrated by the appearance of numerous similar four-coordinate zirconium species along with di-chloro-bridged dimers. Characterization of the molecular components in kinetoplast-mitochondrial DNA of Trypanosoma equiperdum.

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Moreover, the substitution of plasma components like anti-idiotypic antibodies and immunoglobulins targeted against a host of antigens may add to its beneficial effects. Conversely to what has been previously reported, bicarbonate did not linearize F1-ATPase kinetics. 165 consecutive untreated retinoblastoma patients admitted to the CM-Hospital, between 1993-2000 were evaluated retrospectively.

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However, our whole-body MRI study further provided evidence of signal alterations in the glutei, erector spinae and shoulder girdle muscles. Isolation and structure of cytostatic steroidal saponins from the African medicinal plant Balanites aegyptica. Colour improvement and stability of white spot lesions following infiltration, micro-abrasion, or fluoride treatments in vitro. It is proposed that the appearance of Erwiniae in the vagina is an important indicator in the prediction of urinary tract infection by Erwiniae. Mycoplasma pneumoniae J-domain protein required for terminal organelle function.

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We investigated whether the analysis of FFPE tissue lysates with RPPA would result in biologically meaningful data in two independent studies. Atazanavir/ritonavir monotherapy as maintenance strategy in HIV-1 treated subjects with viral suppression: 96-week analysis results of the MODAT study.

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Pathological exam described serous pericarditis with chronic inflammatory infiltrate, xanthogranulomatous reaction intricated in the pericardium and mesothelial hyperplasia. Twenty-six adult COPD patients with dyspnea were randomly assigned to two groups.

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Abnormal sensory findings secondary to monocular cataracts in children and strabismic adults. Tsix, a transcript anti-sense to Xist, participates in the choice of the inactive X and in Xist regulation through as yet unknown mechanisms.

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We described a complication during percutaneous coronary intervention. Regulation of anthocyanin biosynthesis in Arabidopsis thaliana red pap1-D cells metabolically programmed by auxins. The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled. There were no significant differences in adiponectin or resistin levels in women with metabolic syndrome when compared with the control group.

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Tiling array results were validated by bisulfite direct sequencing and qPCR. Myotonic dystrophy (DM) is the most common neuromuscular disease with adult onset (incidence 1 in 8000). On that basis, the minimal mechanism of the above reaction was postulated. Chenodeoxycholic acid (CDCA) also exhibited these effects, whereas deoxycholic acid and litocholic acid were ineffective.

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Thus, successful screening of solid phase libraries can be accomplished using selected sequences of the target enzyme. The pathomorphological alterations of the vegetative ganglia of the stomach, intestine and celiac plexus were found by the authors to be identical in the dogs subjected to laparotomy and in those dead of diffuse peritonitis within the first 3 days. the identification of specific morphological structures and the compartmentation of proteins, indicate that this layer is a specific region of mitotic cells. Evidence to suggest that clofibrate influences pulmonary surfactant metabolism. We abstracted information about endocrine abnormalities from their medical records.

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Both visual and quantitative sublobar source analysis of scalp ictal EEG can predict surgical outcome in most cases after AMTL and complement non-invasive presurgical evaluation. Chronic adaptation of dog parathyroid function to a low-calcium-high-sodium-vitamin D-deficient diet. These data further support the coupling of cholesterol efflux to the activation of membrane and transmembrane signaling events leading to the activation of a unique signaling pathway involving the cross-talk between cAMP and tyrosine kinase second messenger systems, thus defining a new mode of cellular signal transduction initiated by cholesterol release. Preface: RECOMB systems biology, regulatory genomics, and DREAM 2012 special issue. The resulting expression was evaluated for truncated and shifted Lennard-Jones fluids by means of computer simulation.

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Major salivary gland tumor extent was routinely assessed by preoperative ultrasonography. The method used was to screen the personnel in a Swedish mechanized battalion serving in Bosnia from March until October 1996 on four occasions: before deployment, immediately after deployment, 6 months after deployment and 1 year after deployment. However, the precise mechanisms by which TZD may possibly affect tubular cell survival after injury remain unclear. Our results indicate that grasses in diculture supported a more species and phylogenetically rich soil mite fauna than was observed for monocultures and that this relationship was significant at depth but not in the upper soil horizon.

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Effect of ovarian steroid hormones on superficial activator calcium in the rabbit uterus. Effect of 4 weeks of basic military training on peripheral blood leucocytes and urinary excretion of catecholamines and cortisol. Although clinical trials with G-CSF have been started for the treatment of myocardial and limb ischemia, our results indicate that caution should be exercised in applying these results to cerebral ischemia. Signalling by PAF is closely linked to adhesive interactions between cells of the inflammatory and vascular systems. However, when aphidicolin was added at the early neurula stage, development could be seen for up to 40 h after addition.

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The serum 25-OHD levels were normal, which excludes a dietary vitamin D deficiency or a reduced hepatic hydroxylation of the vitamin. pneumoniae were collected from November 2002 through April 2003. The targeting of hepatic TXNIP by quercetin and allopurinol may have therapeutic implications for prevention of type 1 diabetes-associated NAFLD. It has been found that the lower the culture temperature, the higher the level of chromosomal aberrations.

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Experimental evidence lends support to the idea that the commitment of interstitial cells into nerve cells is the first morphogenetic prerequisite for emergence of head structures, when the number of nerve cells increases. Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals. It can supplement the RNFL thickness as an indirect gauge of ICP and is particularly helpful in patients with secondary optic atrophy.

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This is a new view of the genome, which sees DNA as not only a simple alphabet but also a more complex geography. Chronic exposure to ultraviolet B wavelengths has been linked to cortical cataracts, and posterior subcapsular cataracts have likewise been associated with the chronic effects of ultraviolet radiation.

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Acute in vivo administration of arsenite rapidly decreased intracellular pools of all ATP phosphate with concomitant increases in inorganic phosphate and phosphomonoesters. The morbidity rate was similar in both groups, but patients with leukocyte filter had a lower incidence of perioperative infections, fever, and hyperdynamic states as compared with patients with the conventional filter. Send-out test requests that met defined criteria were reviewed by a rotating team of doctoral-level consultants and a genetic counselor in a pediatric tertiary care center. Warming the scrotum did not affect this cold-induced increase in food intake.

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Flutamide treatment increased the expression of BMP4 mRNA on GD50 and GD108 and BMPR-IB mRNA on GD50. PhysioNet: a Web-based resource for the study of physiologic signals.

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We show that initially, only a small population of cells (including both quiescent neural stem cells and transit-amplifying cells) responds to Shh in regions undergoing neurogenesis. The assay could detect the presence of ACP and, or, some of its metabolites in horse urine for at least 25 hours after intravenous injection of 0.1 mg kg-1 ACP maleate, but because of non-specific interference, horse serum could not be used.

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A survey of sex differences in 249 pemphigus patients and possible explanations. The racemose form of brain cysticercosis arises from an intense proliferation of the bladder wall after the scolex part has degenerated. Apurinic apyrimidinic endonuclease/redox effector factor 1 (APE1/Ref-1) protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through its independent activity as a redox transcriptional co-activator.