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To assess the efficacy of fertility-sparing treatment using medroxyprogesterone acetate (MPA) for endometrial carcinoma (EC) and atypical endometrial hyperplasia (AH) in young women. Perceptions of authorship criteria: effects of student instruction and scientific experience. Results after hypoglossofacial anastomosis are compared with those obtained by faciofacial anastomoses (published in 1980). In this study, helium-neon laser irradiation produced no measurable benefit on wound healing.

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Some major problems are described and an interview model is proposed as one method of helping the student to cope. Rarely, systemic granulomatous and autoimmune diseases, and to lesser extent acute hypersensitivity reactions can be seen. Genetic analyses identified Ses1 as a significant quantitative trait locus influencing the carrier state of 129S6 mice following a sublethal challenge with Salmonella enterica serovar Enteritidis. Western Blot analysis indicated a specific band at approximately 70 kDa in the membrane fraction of SV40-HCEC and MDCKII-BCRP cells.

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Effect of pH on protein adsorption to hydroxyapatite and tricalcium phosphate ceramics. Infected mice exhibited increased spontaneous and cholecystokinin (CCK)-induced contractions of longitudinal smooth muscle. 3 The vasodilatation induced by methacholine was blocked by atropine and by chemical sympathectomy of the hypothalamus with 6-hydroxydopamine. Pseudomyxoma peritonei--two novel orthotopic mouse models portray the PMCA-I histopathologic subtype. Prednisolone and cyclophosphamide were given to the patient, but clinical symptoms and chest radiographic findings worsened.

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In the postoperative period, almost all the patients had microhematuria, 1 subject having massive bleeding into the retroperitoneal cavity that required nephrectomy. Although these highly conserved, transcriptionally active CTCF-YY1 co-bound regions are often promoter-proximal, gene-distal regions show similar molecular features. This paper presents a Bayesian hierarchical modeling framework for the probabilistic estimation of activated sludge process parameters. Effects of DPL at mercury-water interfaces and estimation of lung surface area. We chemically mutagenized human HeLa cells and validated our ability to isolate mutants at test diploid loci.

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Also, the decreased HDAC2 activity was due to protein modification by aldehydes and nitric oxide products. The pattern of the SBA profile in relation to the severity of the liver disease suggested that hepatocellular excretion is the most sensitive step in the enterohepatic circulation of the bile acids. Small case series reporting the initial experience with ESCP have been superseded by comprehensive reports of large cohorts. All but one of the antigens (Cyn d Bd200K) were found to react with human IgE from sera of BGP-allergic patients. Maximum-likelihood regression with beta-distributed dependent variables.

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The predisposition to LDL oxidation during copper-catalyzed oxidative modification and its relationship with LDL alpha-tocopherol concentration was studied in 41 control subjects. In patients of group C compared with those of group A fewer complaints and muscle tenderness in the hands and fingers were noticed, and more cases with lowered back strength and cinesalgia of the neck were observed. The acute effects (hypothermia, sleeping time) of a single ethanol injection were also unaffected by these peptides. The disadvantage of these archwires is that there are different types of teeth in the mouth and different forces are therefore needed to rectify their position.

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Management of patients with malignant lymphoma: a comparative study with cyclophosphamide and vinca alkaloids. injection of propranolol (0.5 mg/kg b.w.) caused marked decreases in the plasma glycerol concentration both in the dogs fasting for 24 h and 72 hrs, whereas the effects of propranolol on the plasma FFA concentration was found only in the early stage of fasting. No changes in BBB permeability for horseradish peroxidase has been found.

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Support is found for an autonomous and independent profession of psychiatric nursing, able to provide a helping response to those in mental distress independent of psychiatry and psychology. The received signals are filtered, QRS complexes and P and T waves are localized, and different waveforms are classified in order to be able to provide diagnosis tools like heart rate variability and turbulence analysis.

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Immunological interactions can be found at different stages, such as blastocyst attachment, trophoblast invasion into maternal tissues, and flow of maternal blood through the placenta. Endothelial dysfunction is considered to underlie the etiopathology of coronary aneurysm. No unifying trends emerged in the analysis of probable responses in the HRQoL domains across profiles.

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BrdU-positive cells reappeared at the bottom of telogen hair apparatus and formed a secondary hair germ. The aim of our study was to assess the clinical outcomes in consecutive cirrhotic patients with a patent TIPS undergoing major extrahepatic surgery. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the processes of peripheral tissue remodeling and fibrinolysis through the regulation of plasminogen activation. Plasmids with low integration efficiencies have proved to be efficient donors of Tn5, while plasmids with very high frequencies of integration could be used directly to generate mutations. A non-linear mathematical model for computerized analysis of mood curves: construction of the model and its application to the mood curves of depressive and schizophrenic inpatients.

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The modified glutamine synthetase was more susceptible to endogenous phenylmethylsulfonyl fluoride-insensitive proteolytic activity, which was inhibited by MnCl2 and stimulated by EDTA. Calculating NMR parameters in aluminophosphates: evaluation of dispersion correction schemes. Clinical usefulness of markers of bone degradation and formation.

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Plasma HIV-1 tropism and risk of short-term clinical progression to AIDS or death. Anti-fatty liver activity of crystalline trypsin in insulin-treated depancreatized dogs. Serum markers of oxidative stress and inflammation were compared in a cross-sectional, case-control design study of 40 male individuals, with or without persistent or permanent AF, who were matched for age, sex, diabetes, and smoking status, known confounding variables for the measurement of oxidative stress. In addition, aldo-keto reductases, which detoxify carbonyl compounds produced by oxidative stress, are present at high levels in the epithelia of the genital tract and Sertoli cells of the testis.

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The medical records of horses that had penile amputation and sheath ablation were reviewed. They were stained anti-neuron specific enolase and anti-Thy 1.1 positive, indicating they are retinal ganglion cells. The value of predicting mortality in patients with severe CAP was similar for IL-6, IL-10 and TGF-beta1. Under AG stimulation, corticotrophs showed considerable variations in structural features probably reflecting differences in their functional state.

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Carcinomas of the temporal bone and paranasal sinuses are a complication of radium administered therapeutically or ingested accidentally by watch dial painters. The influence of mechanical loading and degradation on the mechanical characteristics of two different materials for suturing, Prolene and Ethilon, is presented. In this study, we aimed to investigate the association of serotonin 2A receptor gene -1438A/G SNP (HTR2A -1438A/G), tryptophan hydroxylase 2 gene -703G/T SNP (TPH2 -703G/T) and serotonin 1A receptor C-1019G (HTR1A C-1019G) with suicidal behavior.

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The activities of glucose-6-phosphate dehydrogenase, malic enzyme, fatty acid synthetase and acetyl-CoA carboxylase (extracted with or without phosphatase inhibitor) in rat liver did not vary significantly during 24 h. Analysis of mortality for adults aged 20-69 in 1970-2 and 1989-92 using population data from 1971 and 1991 censuses.

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Subacute thyroiditis and concurrent suppurative thyroiditis in one case Evidences for increased levels of neurohypophysial principles in their plasma. Testosterone propionate treatment reduced proenkephalin expression in the diagonal band of Broca, the caudal preoptic area, and the bed nucleus of the stria terminalis. Estimation of renal function is crucial for a number of clinical situations. Experimental and density functional theory and ab initio Hartree-Fock study on the vibrational spectra of 2-(4-fluorobenzylideneamino)-3-(4-hydroxyphenyl) propanoic acid.

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Large numbers of peripheral blood T cells clonally develop into allorestricted anti-viral cytotoxic T cell populations in vitro. Cre-mediated recombination results in a deletion allele which phenocopies our previously reported Smad2(DeltaC) null mutation. Occupational exposure in patients with the antisynthetase syndrome.

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The cobalamins are B12 cofactors with a reactive cobalt-carbon bond at their core and support the activity of two mammalian enzymes that are both medically important. Addition of profilin to polymerized actin causes it to depolymerize until a new steady-state, dependent on profilin concentration, is achieved.

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Renal tissue was processed for light microscopy, and for HO-1 enzyme activity, assay and for Western blot analysis. Blockade of B7 co-stimulation with murine CTLA4-Ig (mCTLA4-Ig) resulted in decreased Th2 cell development as determined by IL-4 and IL-5 cytokine production in vitro. Plasma renin activity (P.R.A.) and plasma aldosterone were measured in twelve patients having hypopituitarism.

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There are also other less obvious applications of retroviruses, such as their insertional mutagenic effects, which may be useful in studies of the genetic factors and biochemical mechanisms involved in, for example, neurotoxicity. This suggests that genetic resistance operates primarily at the level of worm establishment. Intravenous insulin treatment in acute stroke: a systematic review and meta-analysis of randomized controlled trials. Ultrastructural observation of the sciatic nerve showed extensive demylination and axonal loss after eight weeks of diabetes induction.

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The elimination of all the chlorinated anilines in fish showed a bi-phasic pattern, whereas the elimination characteristics of the tetrachlorobenzene are in agreement with a one-compartment model. Hox-5.1 transcripts were detected in mouse embryos, in adult mouse testis, kidney, heart, and intestine, and in mouse embryonal carcinoma cells treated with retinoic acid.

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In two-color microarray experiments, well-known differences exist in the labeling and hybridization efficiency of Cy3 and Cy5 dyes. As a contemporary report this study contributes to the growing knowledge required for developers of medical software and decision support systems to better understand the needs of end-users. zfAhR2 is homologous to previously cloned PAS proteins within the basic helix-loop-helix and PAS domains.

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The results showed that the NLR and PLR may have added value in the early diagnosis of LC, but further research is needed to confirm these results. The response on the whole was favourable and we suggest that this form of patient education could be helpful in primary care.

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We conclude that SNPs can be used to generate a time series for nuclear markers from ancient material, and thereby to study selection on genes over time. Lack of association between plasma leptin levels and appetite in children with iron deficiency. To investigate auditory perception, speech production, and language ability of prelingually deaf toddlers with cerebral palsy (CP) who were implanted within a sensitive period and who received proper speech therapy. The expression of cathepsin B is of prognostic significance in non-small cell lung cancer, and ranges directly after the pN and pT stages in multivariate statistical analysis. Building a psychiatric-medical liaison: observations of the process.

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Adrenaline stimulates acid production in isolated pig and human parietal cells. The efficacy of recombinant vaccines against white spot syndrome virus in Procambarus clarkii. Chondroitin sulfate was administered orally to six healthy volunteers, six patients with rheumatoid arthritis and six patients with osteoarthritis. One genus can be differentiated because it is highly correlated with another highly differentiated one.

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Ethanol potentiates GABA- and glycine-induced chloride currents in chick spinal cord neurons. The conclusion is that altered regulation of autophagic proteolysis decreases susceptibility of older cells to lysosomal degradation, and it may lead to the accumulation of altered organelles and membranes.

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We tested the hypotheses that endothelial expression of the tight-junction protein, zonula occludens-1 (ZO-1), would be altered during experimental sterile corneal inflammation and that endothelial cell density (ECD) would remain unaffected. Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne viral zoonosis widely distributed in Africa, Asia and eastern Europe. To investigate the role of junctional adhesion molecule-A (JAM-A) in the pathogenesis of systemic sclerosis (SSc).

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Similar bands corresponding to the major proteins of each species of bifidobacteria were observed. N-glycan profiles were obtained for five different fractions: total plasma, isolated IgG, IgG-depleted plasma, and the bound and flow-through fractions of protein enrichment. To determine survival, long-term tumor control, and the effects of irradiation for stage II seminoma. Pacing experience with the atrial screw-in leads at the Singapore General Hospital. Delay of blastocyst implantation in the mouse by ovariectomy of lactation.

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These results indicate that EB and EE may inhibit the metabolism of drugs metabolized via CYP2C9 and CYP2E1, and have the potential to increase the toxicity of the drugs. The patient had atrial septal defect, sensorineural hearing loss, polycystic ovaries, hirsutism, glomerulosclerosis, dental anomalies, and low intelligence.

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EFFECT OF LIMINAL CARBON DIOXIDE CONCENTRATIONS ON THE RESPIRATION FOLLOWING TRANSSECTION OF THE BRAIN STEM AT VARIOUS LEVELS Restoration of wild-type activity to mutant p53 offers promise to eradicate cancer cells using novel pharmacological agents. The slow-release tablets were preferred by 15 of 18 children and their families when the effects, side effects and dosage were evaluated.

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The BMRES group of 17 persons is described and details are given of the trek to 5400 m. In idiopathic acquired sideroblastic anemia, ALAS mRNA for both isozymes was normal and enzyme activity was slightly elevated. Specific labeling could be detected in different cell types of human placenta, dependent on the developmental stage. In community dwelling elderly, those with vascular disease were at higher risk of developing apathy but not depression. We investigated the effect of PRP injections in patients with knee OA based on decreasing pain, improving function, global assessment and changes regarding joint imaging.

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We here show that synthesis of IL-6 by human mononuclear phagocytes exposed to recombinant human (rh) LIF is preceded by an increase of IL-6 transcript levels as a result of transcriptional activation of the IL-6 gene. Factors controlling the size of DNA loops in frog embryos and Friend erythroleukemia cells. In the presence of helical peptides, a PMP1 fragment, or an annexin fragment, the DPC local dynamics are not affected whereas the DPC aggregation number is increased to match an appropriate area/volume ratio for accommodating the bound peptides. Variation in the appearance of the lateral liver scan with patient position. The retention behaviour of amino acids was studied in hydrophilic LC on zwitterionic stationary phases.

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PBPRP2 is abundantly expressed in all adult gustatory organs on labellum, legs, and wings and in the internal taste organs on the proboscis. A luciferase reporter gene assay and mRNA stability tests revealed that the expression of GADD153 was regulated at both the transcriptional and post-transcriptional levels following celecoxib treatment. Simultaneous insertion of DZP suppository and oleaginous base significantly decreased maximum concentration (C(max)) and area under the blood concentration-time curve (AUC) of plasma DZP concentrations.

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Absorption, distribution, and excretion of sodium fluoroacetate (1080) in rats. Nutritional ecology of obesity: from humans to companion animals.