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Two different protein kinase activities phosphorylate Ras2 protein in Saccharomyces cerevisiae. Detection of inspiratory resistive loads after anaesthesia for minor surgery.

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A possibility of modulation of DNA topoisomerase I activity by topotecan due to complexation with several sites of a supercoiled DNA molecule is discussed. Pulmonary function was assessed by spirometry, and in 5 patients, inspiratory function was assessed with esophageal manometry. Examination of RA content in the 0-2-h urine samples after oral administration of MPH indicated the presence of higher levels of l-RA (d-RA:l-RA, 0.37), whereas after intravenous MPH, there was no significant difference between the amounts of RA enantiomers. Ambulatory behaviors of 21, 45, and 60 day old rats exposed to methadone (5 mg/kg) during gestation and/or lactation were studied by assessing locomotion in an activity cage, open field, and activity wheel, and latency times to step down from an elevated platform.

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The short-term efficacy (three months or less) of electromyographic biofeedback on the control and strength of six lower extremity muscles in twenty-two hemiplegic patients was investigated. Laminins are large heterotrimeric proteins composed of alpha, beta, and gamma chains. Echocardiographically measured EFT was significantly higher in the patients with GDM. The basis for the frequency of the AML phenotypes is unclear, although there is a rough concordance with the frequency of marrow precursor cells of different lineages.

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A primary outcome measure of endophthalmitis and secondary outcome measure of risk factors for endophthalmitis were studied. Preclinical studies were designed for many animal models and they have contributed to the translation to the human clinic. A note on the use of pigeons for the assay of digitalis products.

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In this study, we tested the hypothesis that these transcriptional coactivators are required for viral IE gene expression during infection of cultured cells. To evaluate the clinical outcome and socioeconomic consequences of occupational asthma (OA). The morphologic findings and histogenetic considerations are reported together with a short review of literature.

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Eight of the 14 patients described had occlusion of one or both transverse or sigmoid sinuses. The incremental cost-effectiveness of sequential screening among male offspring, sequential population-wide screening, and genotypic screening is 41000, 124000, and 161000 Eero/LYG, respectively.

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UBXN-2 and CDC-48 coimmunoprecipitated with AIR-1 and the spindle alignment defect was partially rescued by co-depleting AIR-1, indicating that UBXN-2 controls these processes via AIR-1. While MNTB cells receive singular calyx-like endings from the AVCN, LSO cells receive projections from a long column of cells in the MNTB. PPARgamma and PPARalpha agonists increased mitochondrial copy number, uncoupling protein 1, medium-chain acyl-coenzyme A dehydrogenase, and carnitine palmitoyltransferase 1, but did not change PPARalpha, PPARgamma coactivator 1alpha, or transcriptional factor A mRNA levels. A new study describes one possible mechanism and reveals a potential new therapeutic target in the treatment of asthma.

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Power functions fitting small-pulse and large-pulse limbs of some transfer curves had different scale coefficients, even though exponent values were the same. In a series of 33 cases, the results were excellent or good in 21.

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Women in the treatment group were receiving therapy for either alcoholism, for being battered, or for mental health problems. The present review discusses the theoretical background underlying the evaluation of diagnoses, possible designs of reliability studies, estimation of the reliability coefficient, the standards for assessment of reliability, and strategies for improving reliability without compromising validity. Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II.

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The time course of changes in cyclic GMP levels in response to EDRF in PCA and RA have also been studied. Primary cilia contain specific receptors and channel proteins that sense the extracellular milieu.

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There are over 600 descendants of one English migrant and his spouse living today. Classification SAR modeling of diverse quinolone compounds for antimalarial potency against Plasmodium falciparum. Circulating gonadotropin and testosterone levels in infertile men with varicocele and sperm counts of less than 10(7)/ml were correlated with testicular Leydig cell density and in vitro testosterone synthesis. A double-blind comparison of clonidine and lofexidine in the management of the opioid withdrawal syndrome encountered several difficulties of a non-scientific nature which eventually forced termination of the trial. While the SAPP2 transcript was present under all of the conditions tested, expression of SAPP1 was induced only by the presence of exogenous protein as the sole nitrogen source.

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Use of symptoms by schizophrenics to monitor and regulate their illness. In all 3 patients hydrocephalus internus was already prenatally diagnosed. Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS. To determine the effects of immunodeficiency, nutritional status, and concurrent systemic disease on peripheral nerve function in acquired immunodeficiency syndrome. in lower respiratory tract samples without finding of other nonmycotic infection.

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This is supported by the fact that EEG slowing was associated with less oxido-inflammatory stress. After TIPS placement, there was marked symptomatic relief and improvement in liver function, but the courses of both patients were complicated by the development of an inferior vena cava (IVC) syndrome caused by segmental stenosis of the suprahepatic IVC just at the outflow jet of the TIPS at 11 and 9 months later. Finally, the proposed scheme is used to illustrate Q-S (complete or anticipated) synchronization between the two-dimensional discrete-time Lorenz system and Fold system, as well as the three-dimensional hyperchaotic discrete-time Rossler system and generalized discrete-time Rossler system.

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Novel algorithms reveal streptococcal transcriptomes and clues about undefined genes. flamarioni baculum is thin throughout the shaft with rounded proximal and distal tips. Platelet-activating factor (PAF) is an alkylphospholipid that has been implicated in tissue damage after cerebral ischemia. After an initial dose titration period, the maintenance dose of felodipine was 5 mg twice daily in 14 patients and 10 mg twice daily in 34 patients. ON MALLEOLAR FRACTURES DUE TO TRAUMAS FROM WINTER SPORTS AND THEIR PREVENTION

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Anti-melanin deposition activity of ceramicines from Chisocheton ceramicus. In this study, we examined IL-6 secretion from culture-activated rat PSCs and its regulatory mechanism. The diagnosis of pediatric nail disorders can be a sign of systemic disorders and diseases.

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Our observations also suggest that endogenous SRIF may modulate and inhibit its own release. Examination for an association with progression and malignant transformation without reinterpretation was performed. After the institution of weekly circuit changes, daily surveillance of intubated patients was performed during 18 of 22 weeks from May through September 1993. HCV has a high mutation rate and therefore high variability, which may be important for evading the immune system and response to therapy. Psychometric properties of the EORTC Quality of Life Questionnaire in inpatient cancer rehabilitation in Germany.

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In order to minimize the effects of minor constituents in the oils, the authors compared conventional safflower oil with oil from a mutant strain of safflower that is rich in oleic acid. Psychometric analyses included internal consistency, test-retest reliability, responsiveness and construct validity. HLF, HLFC and HLFP cells pretreated with low concentration were retreated by high concentration of HQ.

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In the wild type, 10 mM of any of the amino acids L-alanine, L-cysteine, L-isoleucine, L-leucine, L-tryptophan and L-valine reduce uptake of any of the three branched-chain amino acids. Other mechanisms are also responsible for resistance since not all resistant strains fully complemented to the wild-type phenotype.

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Polymerase chain reaction amplification of rhinovirus nucleic acids from clinical material. Etofenamate levels in human serum and synovial fluid following iontophoresis. Next, we plotted the number of cancers cell lines exhibiting specific G/T genotypes in 746 cancer cell lines of the Sanger Institute database.

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Assessment of basic human performance resources predicts operative performance of laparoscopic surgery. Discovery of a sexual cycle in Aspergillus lentulus, a close relative of A. A semi-automatic method for quantification and classification of erythrocytes infected with malaria parasites in microscopic images.

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Study of the elution mechanism of sodium aryl sulfonates on bare silica and a cyano bonded phase with methanol-modified carbon dioxide containing an ionic additive. Investigation of the secondary neuropsychiatric disorders occurring with right brain dysfunction contributes to understanding the pathophysiology of idiopathic psychiatric syndromes.

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Administration of mesenchymal stem cells (MSCs) has been shown to improve renal function in rodent models of chronic kidney disease (CKD), in part by reducing intrarenal inflammation and suppressing fibrosis. The procedure of control of sanitary preventive, disinfection and sterilization measures during pre-licensing expertise of organization medical activities is discussed. CPAP failure in preterm infants is associated with increased risk of mortality and major morbidities, including BPD. The second case received surgery followed by chemotherapy with cisplatin and doxorubicin, but she died 2 months later.

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Periods of heightened vulnerability to weight gain have been identified, and research supports the notion that obesity has its origins in early life. The objective of this article is to illustrate the statistical technique of spline regression, an under-utilized tool in clinical research. Accompanying citizen of persons with traumatic brain injury in a community integration project: An exploration of the role. The central nervous system (CNS) affects reflexes that control urine storage and micturition, and norepinephrine and serotonin play a key role in maintaining storage capability by means of contraction of the external striated muscle of the urethral sphincter.

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With the increasing flow of biological data there is a growing demand for mathematical tools whereby essential aspects of complex causal dynamic models can be captured and detected by simpler mathematical models without sacrificing too much of the realism provided by the original ones. For a compressor cascade, the particle impact rate increases proportionally with the flow inlet angle and the erosion rate on the pressure side surface of blade are related to the surface or coating materials. The results of ophthalmic examinations of the patient were consistent with orbital cellulitis. A versatile multi-input device based on an x-y recorder was designed for the study of the Pulfrich effect.

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The AM-PAC can assess a broad range of function in patients with complex medical illness. Orolingual hematoma as differential diagnosis can be excluded by CT-scan.

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The phenotype of mutations of G2655 in the sarcin/ricin domain of 23 S ribosomal RNA. These peptide vaccines induced both helper T-cell responses and production of antibodies that were specific for influenza Aichi hemagglutinin but not for the major histocompatibility complex binding frame in mice bearing Ak or Ab. Relationship between doppler-derived left ventricular diastolic function and exercise capacity in patients with myocardial infarction.

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Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). The integrated perspective needed to quantify the net effect of N on greenhouse-gas balance is being addressed by the NitroEurope Integrated Project (NEU). It should thus be noted that increased anaerobic catabolism by microbes and impaired transport of end products may cause gas-formation in patients with diabetes mellitus. Arm circumference and other factors in children at high risk of death in rural Bangladesh.

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In particular, accumulation of non-methyltetrahydrofolates due to altered partitioning of folate metabolism at the level of methylenetetrahydrofolate is of interest. Counts of daily increments were used to estimate the location of the first opaque growth zone, which was completed before the first assumed birthday. Canadian C-Spine Rule study for alert and stable trauma patients: II. DAT individuals were also more likely to allow inappropriate information to actually drive responses (i.e., increased intrusion errors). Sanitary and Hygiene examination of light drinks such are: kvass, beer, fruit, mineral and other drinks, juices and none standardized drinks in Tbilisi in 2000-2004 showed that this products typically, mostly produced by small commercial enterprises, are typically produced out of sanitary-epidemiological and sanitary-hygiene norms and regulations.

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Expressions of c-Fos and NADPH-d in the related brainstem during vestibular compensation Smad protein family members act downstream in the TGF-beta signaling pathway mediating various biological processes, including cell growth, differentiation, matrix production, apoptosis and development.

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With the wealth of literature available, searchers trying to find PHC-specific citations can feel overwhelmed. Interestingly, of the 23 multi-organ recipients who survived at least 3 years, none died or required retransplantation. Little is known about sperm-binding proteins in the egg envelope of nonmammalian vertebrate species. The repeat has a unit size of 39 bp, is highly conserved and is present in at least 14 copies. The software is implemented in the R language and can be downloaded from the Bioconductor project website (http://www.bioconductor.org).

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PEH was associated with advanced age and significant comorbidity. The measurement of immunoreactive gamma-GTP protein in sera appears to be useful for the detection and monitoring of certain malignant tumors. The reasons for focussing on those parameters, on which the European Guidelines and now the German programme are based, and their significance in the long-term effectiveness of this programme are explained. Immunohistochemical evaluation of the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on dopaminergic nigrostriatal neurons of young adult mice using dopamine and tyrosine hydroxylase antibodies.

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These findings indicate that high-density, oligonucleotide-based microarrays can be successfully used as tools for the detection of chromosomal rearrangement in clinical samples. To determine the effect on survival after transarterial chemoembolization (TACE) in patients with unresectable hepatocellular carcinoma (HCC). Isolation and amino acid sequence of flavostatin, a novel disintegrin from the venom of Trimeresurus flavoviridis. Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration. On the pathogenesis and therapy of dementia of the Alzheimer type: some neuropathological, biochemical, genetic and pharmacotherapeutic considerations.