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Results and long term follow-up for 1581 patients with metastatic breast carcinoma treated with standard dose doxorubicin-containing chemotherapy: a reference. Studies of hepatosplenomegaly associated with Schistosoma mansoni infection and exposure to Plasmodium infection indicate that differences that occur over 1-2 km in levels of Plasmodium transmission are related to the degree of exacerbation of hepatosplenomegaly and that Plasmodium falciparum schizont antigen (Pfs)-IgG3 levels may be a marker for the differing levels of exposure. Against this background, quantitative structure-activity relationship (QSAR) models have been developed here for the toxicity of ILs against the green algae Scenedesmus vacuolatus using computed descriptors with definite physicochemical meaning. Other significant toxic effects were neutropenia, asthenia, tumor pain and transient liver enzyme elevation. To examine the training periodization of an elite Australian Football team during different phases of the season.

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In singleton pregnancies, maternal drug dependence is associated with an increased risk of placental abruption. Next to strategies to optimize maternally acquired immunity in individual foals, current research explores other options to modulate immune responses in foals. Preterm animals endowed with limited fat stores, thus, minimal available glycerol, would be incapable of survival. Reparixin, an inhibitor of CXCR2 function, attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord.

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BMP-2 and BMP-6 mRNA levels were higher in the normal than the necrotic site (normal/necrotic: 16.8/6.8 and 1.75/1.64, respectively). If thymidine-(3)H monophosphate is supplied, a small amount of radioactivity is incorporated into both nuclear and chloroplast DNA in proportion to the abundance of these DNA components. Clinical characteristics of late-onset severe pneumonia after allogeneic hematopoietic stem cell transplantation The central nervous origin of the swimming motor pattern in embryos of Xenopus laevis.

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Driven by their beneficial effects on human metabolism, isoflavonoids have gained considerable importance reflected by an increased number of isoflavone-rich foods, food supplements and pharmaceutical products on the market, mainly derived from soy and red clover. pestis-specific frameshift mutation, also failed to produce aerobactin. The protective effect for hypertension on Hispanics had been disappearing over time (P interaction race/ethnicity and survey year .002). Using NO imaging with diaminofluoresceine in cultured hippocampal neurons we analyzed the time course of neurotrophin-induced NO signals. Predictive factors determining the survival time of patients are strongly associated with morphological features of tumours.

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The mean annual incidence rate of early-onset MG was constant at 3.5 x 10(-6). Phenotypic polymorphism of the blood by the ABO system in the clinical picture of mengingococcal infection in children Genetic analyses have revealed both positive and negative regulatory interactions of Tailless with various target genes, leading to the idea that, like many other nuclear receptors, Tailless mediates both activation and repression of transcription. Viral DNA replication, late viral protein expression, and production of infectious progeny were characterized. Similar effects occurred in CA3 pyramidal cells and dentate gyrus granule cells when their major glutamatergic afferents were stimulated.

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The effect of this susceptibility must be large enough to overwhelm the opposing effect of decreased UV intensity at higher latitudes, and this emphasizes the dangers of excessive solar exposure to fair-skinned individuals. The preliminary structural and functional characterization of a recombinant PcF homologue, N4-rPcF, is reported. We prepared a series of dendrimers with a bidentate phosphine core ligand having carboxy groups at the peripheral layer. Propagation of sinusoidal electrical waves along the spinal cord during a fictive motor task.

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We suggest that impaired macrophage phagocytosis in Cav-1 knockout mice could have implications for altered innate immunity against pathogens, the regulation of inflammatory responses, and the development of autoimmune disease. Outpatient visits (July 29, 2008 to October 27, 2011) are included with a 200 patients random sample calculation. The Drosophila eye has long provided a beautiful system for understanding various aspects of retinal-cell differentiation.

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On the possibility of treating leg ulcers by skin transplantation ambulatory patients Treatment with insulin and its analogs in pregnancies complicated by diabetes. Generalized estimating equations evaluated changes in withdrawal and craving, depression and anxiety symptoms, and alternative reinforcers over time, between participants who were smoking at 6-months and participants who were abstinent (confirmed with carbon monoxide) at 6-months.

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This was the first multi-disciplinary service operating permanently within an Australian health service. The measures include land use change or fertiliser reduction, reduction in atmospheric nitrate and ammonium deposition, and the introduction of water meadows or connected wetlands adjacent to the river. The frequency of stressful life events, the characteristic psychopathological features, and the course of relapse were studied in 22 schizophrenic patients who relapsed while on maintenance neuroleptic medication and 27 noncompliant patients off treatment. Respiratory health status of 3098 Canadian grain workers studied longitudinally.

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Gay grows up:an interpretive study on aging metaphors and queer identity. Review concerning the prevention of rhesus immunization using anti-D-gammaglobulin

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This information contributes to the understanding of potential risks associated with silage preservation and contamination of livestock feed with manure-borne pathogens. Behavior disorders in children following a short period of hospitalization. The authors studied the membrane-stabilizing effect of two water-soluble preparations of antioxidants, analogues of ionol, in thermal burns. Current hazard assessment approaches are analyzed in terms of data availability and quality, and covering non-test tools, the integrated testing strategy (ITS) approach, the adverse outcome pathway (AOP) concept, methods for assessing uncertainty, and the issue of explicitly treating mixture toxicity. Mutations in the Complex III Assembly Factor Tetratricopeptide 19 Gene TTC19 Are a Rare Cause of Leigh Syndrome.

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In Experiment 2, we introduced a difference in exploration mode between the two modalities (visual exploration was parallel while haptic exploration was serial or vice versa). This study describes the method of knowledge acquisition for the identification of the triggering symptoms used in the reasoning of three experts for the diagnosis of schizophrenia. The effect is more pronounced in women and in younger subjects, and is not conveyed by cardiopulmonary comorbidity. All suspected cases of VAP were confirmed by a positive quantitative culture of a respiratory sample. These results suggest that manipulations, such as artificial horizons, that provide stable visual representations of the static environment within which the motion occurs may provide important health and safety measures for individuals working in modern vehicular conveyances.

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Knowledge, attitudes, and practices of non-medical students in traditional and complementary medicine in Gharbiya governorate, Egypt: a cross-sectional study. Chemical constituents and pharmacological action of Polygonum cuspidatum Sieb. Renal transplantation in patients with amyloidosis due to familial Mediterranean fever.

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The decoloring capacity of the selected resins (D296 and Dt) was compared by the dynamic adsorption decolorization experiments. Like its orthologues from invertebrates, SmCAR contains a P box sequence of ESCKA in the DNA binding domain.

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Thus, the category selectivity at the population level resulted from averaging responses of a heterogeneous population of single units. To simplify the analysis, the steady-state conditions have been considered here in order to perform a linear stability analysis of the hydrodynamic equations with respect to the uniform shear flow state. By analogy with structures on Earth, we propose here that the faults are in fact the surface expression of dykes, and not of large-scale tectonic movements. Strong ID1 expression was significantly associated with increased tumour thickness, and significantly reduced survival. Biochemical methods in the treatment of alcoholism, with special reference to antabuse.

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Differential association of oral and transdermal oestrogen-replacement therapy with venous thromboembolism risk. A lamellar hybrid assembled from metal disulfide (MoS2 , WS2 ) nanowall arrays anchored on nitrogen-doped carbon layers is developed via an in situ hybridization strategy through a synergistic pyrolysis reaction of thiourea and oxometalates. Furthermore, the relative representation of the cues often changes as a function of the time resolution of the code, implying that information about multiple cues can be multiplexed onto individual spike trains. Toxicity and toxicokinetics of a phosphorothioate oligonucleotide against the c-myc oncogene in cynomolgus monkeys.

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For patients with unresectable disease or where surgery would not be appropriate, radiotherapy appears to be an effective therapeutic option. An efficient enantioselective approach to cyclic beta-amino acid derivatives via olefin metathesis reactions. Net migration measures take account of the direction of migration flows, but our understanding of migration can be extended using population turnover and churn as measures of population stability. Reversible integration of the dominant negative retinoid receptor gene for ex vivo expansion of hematopoietic stem/progenitor cells.

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Colonization by Alcaligenes xylosoxidans in children with cystic fibrosis: a retrospective clinical study conducted by means of molecular epidemiological investigation. Application of Hilbert-space coupled-cluster theory to simple (H2)2 model systems. Taken together, these results demonstrate that the Smad3 protein is involved in TGFbeta-dependent regulation of steroidogenesis. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase.

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Although further development of this philosophy is required, this ethic shows great promise as a guide to decision making in nursing. Depletion of Acb1p resulted in the differential expression of genes encoding proteins involved in fatty acid and phospholipid synthesis (e.g. Concomitant hysterectomy, increased BMI and bladder injury do not alter good long-term results of TVT. Heavy labeling due to specific concanavalin A binding was detected on the plasmalemma of undifferentiated carcinoma cells lacking zymogen maturation, neoplastic cells of intermediate differentiation with only occasional zymogen granules, and highly differentiated acinar carcinoma cells containing numerous cytoplasmic zymogen granules.

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Plasma renin activity (PRA) and plasma levels of catecholamines, angiotensin II (AII), atrial natriuretic peptide (ANP), and arginine vasopressin (AVP) were measured. The secretory activity of the hypothalamo-hypophyseal system in the frog Rana temporaria under conditions of dehydration has been studied histologically using two parameters, the amount of stained neurosecretory material and the amount of neurosecretory material labelled by a radioactive precursor. Cosegregation information also declines with increasing training data size, and its persistence over generations is lower than that of LD, suggesting the need to model LD and cosegregation explicitly.

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In a one-day field experiment, periphyton grown in fast-flow conditions and dominated by opportunistic green algae were exposed to light levels corresponding to sub-saturating (forest shade) and saturating (open stream section) irradiances, and to N and P nutrient additions. In only 1 of 50 men were there numbers of motile spermatozoa possibly compatible with fertility. Acute, non-selective beta-blockade is well tolerated by transplant recipients, but significantly attenuates beneficial functional effects of sympathetic reinnervation on exercise performance.

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These cases provide an augmented training set for constructing a new computer model of the cases of interest. The effect of retained placenta and metritis complex on reproductive performance in dairy cattle -- a case control study. The HFE mutations associated with Hereditary Haemochromatosis are not more common in Irish CD patients. Although the role of insulin sensitivity is not negligible, insulin secretion appears to be the major determinant of diabetic control in overt type 2 diabetic patients who are treated with metformin alone or with a two-drug therapy combining metformin and glyburide. In this paper I focus on NAC due to phenotypic plasticity of neutral alleles.

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Depletion of H1c, H1d, and H1e causes pericentric chromocenter clustering and de-repression of major satellites. Inherited deletion of chromosome (21p-) in a child with congenital malformation and psychomotor retardation. Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity. Qualitative changes with pergolide were observed with some mice showing hyporeactiveness, ptosis, slowed respiration and placing loss. Eight animals, including one control, were employed in this study, yielding data from 32 tumours as well as adjacent adipose and connective tissues.

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The distribution of nerves, monoamine oxidase and cholinesterase in the skin of the camel (Camelus dromedarius). This report describes a 74 year old Caucasian man, with no known allergies, presenting severe myalgia, muscle weakness, jaw claudication, and fever.

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Quantitative scintigraphy of the joints in psoriasis arthropathica Atmospheric aerosols: increased concentrations during the last decade. Moreover, each landmark is centered into a spherical confidence region that can help the clinician in a subsequent manual refinement of the annotation. The present results show that PAS may increase the amplitude of later corticospinal volleys, consistent with a cortical origin of the effect of PAS. Muramyl peptides in mammalian tissues and their effects at the cellular level.

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We apply MASTOR to data on high-density lipoprotein cholesterol from the Framingham Heart study. Abusive behaviour by family carers towards people with dementia is common, with a third reporting important levels of abuse and half some abusive behaviour.

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To assess the fitness to drive of psychiatric outpatients in a sample representative of current clinical practice. Neuropeptide Y messenger ribonucleic acid in the magnocellular hypothalamo-neurohypophysial system of the rat is increased during osmotic stimulation. A gene island with two possible configurations is involved in chromatic acclimation in marine Synechococcus.

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Assay method of glycosidase and glycosyltransferase activities using enzyme-linked immunosorbent assay Atopy is known to play an important role in the asthmatic disease. We measured CCL3L1 copy-number in 1136 RA cases from New Zealand (NZ) and the UK, 252 NZ T1D cases and a total of 1470 controls. The major adducts formed in he interaction between tobramycin and ticarcillin have been recently isolated in pure form in our laboratory.

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Hereditary nonpolyposis colon cancer is a common hereditary disorder caused by the germ-line mutations of DNA mismatch repair (MMR) genes, especially hMLH1 and hMSH2. To compare patients treated for heart failure in relation to the management in general practices versus hospital admission. (4) Predicted gestational age by transverse cerebellar diameter nomogram for singletons provided satisfactory correlation for twins.

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