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The duration of biological activity of pindolol following short and long term application was tested using a modified isoproterenol-sensitivity-test. Among them, we first focused on determining the functional significance of the interaction between HBx and hepatocystin. The purpose of the present study was to evaluate the clinical outcome of CT-guided high-dose-rate brachytherapy (CT-HDRBT) in patients with unresectable hepatocellular carcinoma (HCC).

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Inhibition of the epidermal growth factor receptor (EGFR) is a fastly developing field in preclinical and clinical cancer research. Case of acute tuberculous sepsis in boy of nine and half years of age The aim of this case report is to discuss the subject of acupuncture in pregnancy and which acupuncture points, or areas, are safe to needle.

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A series of silver alkylcarboxylates, C(7)H(15)COOAg, C(13)H(27)COOAg, and C(17)H(35)COOAg, have been prepared and the thermolysis of those silver alkylcarboxylates in the presence of various alkylamines, C(8)H(17)NH(2), C(12)H(25)NH(2), and C(18)H(37)NH(2), with no use of solvent was conducted at 120 or 180 degrees C for 5 h, providing spherical silver nanoparticles stabilized by alkylcarboxylates and alkylamines. Statistical considerations on the frequency of side effects of drugs A new access incision for the extirpation of intraoral malignancies has been used in 16 cases, and it is described--together with its apparent advantages. Histological findings of the small kidney revealed ischemic atrophy.

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We investigated the effects of grapefruit juice on the pharmacokinetics of sertraline in healthy volunteers. Bacampicillin was given as tablets or syrup in doses of 400 mg three times per day for seven days to twelve subjects.

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We constructed a model humanized system in which human ICAD-L and CAD proteins expressed in DT40 ICAD/CAD double knock-out cells could rescue both DNA fragmentation and stage II chromatin condensation. These studies explore the effects of changes in seawater chemistry, as predicted by climate models for the end of this century, on marine biota. The relation of growth to the lethal damage induced by ultraviolet irradiation in Escherichia coli.

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Treatment of hormone-refractory prostate carcinoma with chemotherapy is purely palliative, and reported response rates have been low. In particular, the in-field and peripheral surface doses from these wedge systems are measured and their clinical differences discussed. Despite studies advocating routine use of medical imaging for patients with suspected acute appendicitis, this study showed that the clinical evaluation is still paramount to the management of patients with suspected acute appendicitis before considering medical imaging. Centrosome abnormalities are frequently seen in a variety of cancers, suggesting that dysfunction of this organelle may contribute to malignant transformation. An analysis of the alpha-adrenoceptor modulation of vasomotor tone at the level of lateral medullary pressor area (LMPA).

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Molecular mimicry leading to crossreactive autoimmune responses has gained strong experimental support in the past decade. Family perspectives on end-of-life care experiences in nursing homes. A wealth of biological and biophysical evidence now suggests that the molecular basis for prion diseases may be encoded by protein conformation.

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The hemolytic potential has been widely used as an in vitro toxicity screen and as a useful indicator of oxidative damage to biomembranes. The constants of DDpyr decomposition in tris-HCl buffer (pH 7.5) and in DMSO are determined (4.5 x 10(-6) and 0.5 x 10(-6) s-1, respectively).

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Chemical lesioning of the ventral subiculum impaired the spatial learning performances in rats. The curative effects of zinc administration were not observed to be influenced by age. By the end of the first year the gross rate of unplanned pregnancy was 1.1 per 100 users of Nova T and 2.1 per 100 users of TCu. Risk/benefit of heparin-dihydroergotamine thromboembolic prophylaxis.

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insidiosa, Aerobacter, Providence group, and most of the Proteus isolates were infectious for mice when injected by the intraperitoneal route. Structure-based drug design was employed to optimize for SHP2 inhibition, and several new protein-ligand interactions were characterized. BM, LM and FM measured using dual-energy X-ray absorptiometry, self-reported dietary information, leisure time physical activity (LTPA) and other factors were assessed one to eight times in 396 girls aged 10 to 13 years (baseline), and in 255 mothers once. We then develop a co-clustering formulation to cluster the genes and the mesh elements, thereby identifying co-expressed embryonic domains and the associated genes simultaneously. Strong associations between human leukocyte antigen subtypes and severe cutaneous reactions due to allopurinol and carbamazepine have been described.

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Occasional inner hair cells were also missing in regions of severe outer hair cell loss. Images of the reconstructions are provided to visually compare the performances of the methods. Management of salivary gland adenoid cystic carcinoma: institutional experience of a case series.

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The incidence of tuberculosis is increasing, and alimentary tuberculosis should be considered in patients from populations at risk presenting with obscure abdominal complaints or unexplained radiologic findings. At the end of 2 years IHH patients with failed puberty or progression of puberty and CDP who lagged behind by more than 2 years by Tanner scale or 4 years per bone age with compelling psychosocial or psychosexual reasons at school or at home were given short courses of 50 mg injection testosterone in an attempt to expedite the onset or progression of puberty. The defecation mechanism of the neorectum is radiologically demonstrated. Two categories and six specified strategies were identified as the interventions.

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This is especially true with regard to identifying adjustment disorder (AD), despite the fact that AD is the most prevalent psychiatric diagnosis in cancer patients. alpha 2PI serves only as a glutamine substrate (amine acceptor) for activated Factor XIII in the cross-linking reaction, and the cross-linking occurs between Gln-2 of the alpha 2PI molecule and a lysine residue (amine donor) of fibrin(ogen) alpha chain, whose position was investigated. A closer examination of the data revealed that among several variables reflecting living conditions, the factors best explaining the variation in age at menarche were adult illiteracy rate and vegetable calorie consumption.

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Hepatitis B virus specific DNA polymerase activity as a sensitive marker of viral replication To compare the outcome of short- and long-term survival of patients with Q wave vs non-Q wave myocardial infarction. Lactic dehydrogenase (LDH) and beta-glucuronidase (bGLU) levels are elevated in the gastric juice of patients with gastric cancer, and these enzymes have been used as a screening test for gastric cancer. If the therapist is attuned to what the patient is saying, this can open up unexplored feelings, experiences, and unprocessed traumatic memories.

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The feasibility of replacement of the caloric test with sinusoidal rotatory stimulations of differing frequencies was investigated in ten normal subjects and seven patients with unilateral labyrinthine paralysis. Shell-gland blood flow was minimal in the absence of an egg and increased gradually to a maximum (5-fold) about 5 h after entrance of the egg into the shell gland. Matrix metalloproteinase inhibitors reduce phorbol ester-induced cutaneous inflammation and hyperplasia.

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Logistic regression was used to assess the relationship between the predictors (telemedicine, hospital level, maternal characteristics) and the probability of a transport. The fine structure of the body wall and the intestine of male and female Litomosoides carinii was studied in sections through the middle and posterior regions of the worms. All patients admitted to the two wards in the 5-month period of the study were invited to participate, with a final sample of 299 participants recruited.

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Here, we investigated whether genetic changes in the S gene occurred during virus persistence in vivo. We conclude, migrated biliary stents associated with perforation distal to the Ligament of Trietz (LOT), may be treated by percutaneous drainage of the abscess and retrieval of the stent from the peritoneal cavity, even when associated with a large intra-abdominal abscess.

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These findings show that the DP cell microencapsulation maintain the capacity for initiating the follicle regeneration and can be considered as a substitute for fresh isolated dermal papillae. The quantities of compounds are sufficient for hundreds of phenotypic and protein-binding assays.

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Neither HD nor PD significantly affected ATRA levels, suggesting that dose modifications of ATRA may not be necessary for children with these forms of renal replacement therapy. The actigraph was modified to incorporate two event buttons which subjects were asked to push hourly to report their level of fatigue. Area of influence (AOI) development: fast generation of receptor-oriented sensitivity fields for use in regional air quality modeling. It is stated that revealing delivery traumatic damages is necessary for a diagnosis of the delivery trauma.

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The cellular toxin sodium azide resulted in the development of an altered mental status, profound metabolic acidosis, cardiac arrhythmia (atrial fibrillation and terminal wide complex arrhythmias), a relative decrease in cardiac output, hypotension and non-cardiogenic pulmonary edema. A CASE OF TORSION OF AN INTRA-ABDOMINAL TESTICLE IN AN ADULT BILATERAL CRYPTORCHID Transport behavior of water molecules through two-dimensional nanopores. Geotrichosis of the respiratory tract associated with non-specific skin changes

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Pathologic angiogenesis is an activated pathway in Hodgkin lymphoma and participates in Hodgkin lymphoma progression. Therefore, the ultrafast intermolecular ET should be coupled with the hydrogen-bonding dynamics occurring in the sub-picosecond time domain. Increased ReHo and functional connectivity in the key regions of the central executive network, such as the orbitofrontal cortex, dorsolateral prefrontal cortex, and the angular gyrus, were found in OCD patients.

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coli enzyme (Trp49 and Trp188) reveals that fluorescence quenching of these residues occurs during the binding of xylose by the wild-type enzyme. The aim of this study was to determine the outcome of Gram-negative rod (GNR) bacteremia, which is an important clinical problem with high mortality rates, and the risk factors for GNR related mortality in our Clinic. Despite receiving increasing attention during the last few decades, the production of microalgal biofuels is not yet sufficiently cost-effective to compete with that of petroleum-based conventional fuels. Concanavalin A-agarose removes mannan impurities from an extracellularly expressed Pichia pastoris recombinant protein.

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Correlation of 2-hour and 4-hour urinary proteins with 24-hours proteinuria in hospitalized patients with preeclampsia. In herniated discs CT shows a focal protrusion of the disc margin, in a bulging annulus it shows a generalized extension of the disc margin beyond the vertebral body margins.

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The in vitro effect of Loxesceles laeta venom on human platelet aggregation was also studied. As is the case today, the innovations in Dutch neurosurgery in the first half of the 20th century were based on the interaction between techniques, knowledge and clinical experiences.

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Phylogenetic analysis of bacterial and archaeal PCR-amplified 16S rDNA genes obtained from Fe(III)-reducing enrichments and separated by denaturing gradient gel electrophoresis revealed sequences related to Deferibacter, Thermotogales (Bacteria) and Thermococcus (Archaea) for which the capacity for Fe(III) reduction had been reported. It discusses the uses of plain radiographs, MR imaging, computed tomography (CT), and CT myelography, in addition to the methodologies of discography, epidural injections under visualization, and facet and nerve root injections. Although this representation is not required for acquisition of the task in the anterograde direction, removal of this representation has a disruptive effect on expression of the task. Our results show that it is possible to make in vitro-in vivo predictions of high, intermediate and low CL(int) drug categories. Females appear to be at much higher risk of developing obesity, IGT, and NIDDM and at a younger age.

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A successful challenge despite advanced second trimester cervical dilatation. This prospective randomized trial compared 14-Fr pigtail catheters and 28-Fr chest tubes in patients with traumatic pneumothorax presenting to a level I trauma centre from July 2010 to February 2012. We enrolled women aged 18-45 years in Brazil and the USA who expected to have sex 1-4 days per month for 6.5 months.

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Evidence regarding safety and efficacy of heparin-bridging therapy for colonoscopic polypectomy remains scarce. An approximately linear correlation between the internalized plasmid and the transgene expression was observed for all the treatments in this study. administration of cisplatin in addition to 4D5 did not improve results. We apply our graph theoretical results to address several interrelated questions: do proteins acquire new domains infrequently, or often enough that the same combinations of domains will be created repeatedly through independent events?

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To determine the impact of preoperative resting hypercapnia on patient outcome after bilateral lung volume reduction surgery (LVRS). The purpose of this study was to investigate the value of UltraFast Doppler ultrasonography (US) for evaluating hepatic vessels in liver recipients. The impact of guidelines on long-term asthma care: a study of hospitalised patients in Malta. The rate constants and activation energies derived are in fact composed of several elementary rate constants. Our lack of knowledge of the basic controlling influences has inhibited investigations in this area, but ultrasound has at least allowed us to begin to scratch the surface of this complex subject.

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Thus, efficient knock-down of hTERT can inhibit glioma cell proliferation and migration prior to its effect on telomere length. One hour after injection, the unconditioned stimulatory effect of dynorphin had dissipated and no longer affected responsiveness to the nipple. The aim of the current study was to evaluate the association of PAI-1 4G/5G polymorphism with coronary artery disease (CAD) risk using a meta-analysis. Thirty minutes after the administration of 0.6 N HCl, the stomach was removed and ulcer indices were calculated. We present and discuss the applicability of a combined intravascular photoacoustic (IVPA) and intravascular ultrasound (IVUS) imaging approach to assess both vessel structure and tissue composition thus identifying rupture-prone atherosclerotic plaques.

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Proinflammatory and anti-inflammatory cytokines play a key role in the pathogenesis of periodontal diseases. Further, a positive relationship was found between the number of painful body areas below the cervical spine, as measured on a body drawing, and the SCL-90 scores. Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells.

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Each column is composed of two lines of tightly opposed round cells, which then elongate into spindle-shaped cells. Subunits of Complexes I, III, IV, and V from skeletal muscle mitochondria isolated from four patients with mitochondrial myopathies were analyzed by immunoblotting.

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To investigate the single nucleotide polymorphism (SNP) of A118G and its interaction with smoking and drinking on oesophageal squamous cell carcinoma (ESCC) risk. Specific immunofluorescence test for the herpes-type EB virus of Burkitt lymphoblasts, authenticated by electron microscopy. Determinants of augmentation of ECG QRS complexes and R waves in patients after hemodialysis. Human babesiosis is a zoonotic tick-borne protozoan infection caused by several species of the genus Babesia.

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Screening effect on the exciton mediated nonlinear optical susceptibility of semiconductor quantum dots. Comparison of Phase-Based 3D Near-Field Source Localization Techniques for UHF RFID.

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Non-steroidal anti-inflammatory drug hypersensitivity in adults and the factors associated with asthma. Peculiarities of respiratory mechanical studies in spontaneously breathing newborn infants. Complete Freund adjuvant was found to be more effective than the Ei Listeria factor. What has also become clear over the past several years is the intimate relationship between the control of cell proliferation and the control of cell fate, particularly the activation of apoptotic pathways. The evolution of the terrestrial vertebrates: environmental and physiological considerations.

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However, CYP1A1 and CYP1A2 protein levels were approximately 100-fold higher than CYP1B1, which could not be detected by either immunoblot analysis or immunohistochemistry in the livers of rats treated with TCDD for 30 weeks at a dose-equivalent less than 35.7 ng/kg/day. Overview of echo-enhanced vascular ultrasound imaging for clinical diagnosis in neurosonology. Moreover, lineage specific gene family expansions are identified, which suggest certain biological demands associated with their ecological setting.