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9-cis retinoic acid (RA) is more effective than all-trans RA at inducing neuroblastoma differentiation in vitro, and has distinct biological properties with respect to its ability to promote apoptosis in N-type neuroblastoma cells. Pesticide Environmental Accounting: a method for assessing the external costs of individual pesticide applications. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Thus, angiotensin II seems to be involved in the mechanism of disrupted diurnal BP rhythm in SHRcp. In addition, pretreatment with a specific PI3K/AKT activator (IGF-1) significantly neutralized the pro-apoptotic activity of lupeol in PCNA-1 cells, demonstrating the important role of AKT in this process.

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Acute upper respiratory tract disorders account for about half of the total disability from acute conditions. The relationship between allelic imbalance on 17p, p53 mutation and p53 overexpression in head and neck cancer. Thus, it is very suggestive to regard the synthetic lethal system prune/Killer-of-prune as the Drosophila model for human neurofibromatosis.

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However, he complained of hearing loss which was worsened by upright position and improved by lying down. Immune response of the mouse in infestation by Hymenolepis nana: behavior of intestinal mast cells The overall clinical effect is a haemorrhagic tendency which, although variable, is severe at times in all patients. They were characterized by memory problems, personality changes, reduced consciousness, brainstem disorders and epileptic seizures. At study entry, APA recognizing GH-producing cells were detected in seven of 26 children in group 1 and in 14 of 60 in group 2.

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In this perspective article, the lessons learnt from the outbreak are used to review the challenges impeding effective implementation of the IHR and to propose policy and strategic options for enhancing its application. This marked hypercholesterolemia is primarily due to elevated levels of very low and intermediate density lipoproteins.

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Sexual function in males following abdomino-perineal resection in Nigeria. Immunoreactive islet cells were not visualized in pig and rabbit pancreas. We report the case of a 53-year-old man in whom rupture of an abdominal aortic aneurysm associated with a large retroperitoneal hematoma caused pressure erosion and destruction of lumbar vertebrae. The degree of resistance of mice with transplanted tumors was determined by difference in survival curves of the immunized and nonimmunized mice. Relationship between a nonlinear response and relaxation induced by colored noise.

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Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse. THE EFFECT OF ANDROGENS ON THE UTERINE AND VAGINAL MUCOSA IN CLIMACTERIC METRORRHAGIAS Usually, there is at least one drug from each major class that can be safely utilised to control symptoms.

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Moderate or severe changes were found in the dorsal spine in 29 patients with OA hips (compared with 12 controls), and in the lumbar spine in 32 patients with OA hips (compared with 10 controls). Pericardial patch venoplasty heals via attraction of venous progenitor cells. Iron and sodium concentration in the serum as well as levels of potassium, magnesium and calcium in erythrocytes were significantly higher in the exposed group. A significant between group difference for 2,5-dihydroxybenzoic acid, only, was demonstrated for the multiple cycles of ETOH exposure.

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This indicates that, in the calf, fermentation of nonabsorbed carbohydrates results in increased breath hydrogen values. The possibilities for surgical treatment is limited and is applied upon strict indications. This implies that maximum pulsar age is spatially dependent on position within the dark matter halo of the Milky Way.

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Device-specific sharps injury and usage rates: an analysis by hospital department. To be authorized to market biomaterials based on collagen, manufacturers now have to prove that at least one step of their process is described in guidelines to inactivate prion, viruses, and bacteria. With the growing emphasis on patient-centeredness and culturally sensitive treatment, it is important to recognize the diversity in values placed on potential losses in HRQoL, particularly mental health outcomes.

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Conventional classification methods fail to consider seasonality in hsCRP and may result in substantial misclassifications in the spring and fall. Here, we discuss mechano-transduction as it applies to protein conformation, cellular organization, and multi-cell (tissue) function. Baseline characteristics, in-hospital complications including secondary intracerebral hemorrhage (ICH), sepsis, pneumonia, pulmonary embolism, deep venous thrombosis, urinary tract infections, and discharge outcomes (mortality, minimal disability, and moderate-to-severe disability) were compared between the groups. To assess ethnic differences in prevalence, levels of awareness, treatment and control of hypertension among Dutch ethnic groups and to determine whether these differences are consistent with the UK findings. Complication rates are equivalent to those of staged procedures.

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Development of a gene capture method to rescue a large deletion mutant of human cytomegalovirus. The inter-specific differences between the birds indicate that the efficacy of methyl anthranilate formulations as a repellent has to be specified for every species. However, much remains to be learned about the nature of their physiological role in the organism, as well as the molecular details of viral entry.

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Educational needs of dietitians were identified by 232 practitioners in Ohio by means of a self-administered questionnaire. The cumulative fragment mass distribution obeyed the double exponential or power law with exponential decay.

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They occurred in 11 of 13 cancer patients and in each of the five patients with benign conditions with median incidences of 2.2 and 0.4 per 1000 glands, respectively. The objective of this study was to characterize the UGT and SULT activities in liver S9 fractions from various species including humans, monkeys, dogs, and rats. On renaturing pp60 in the presence of globin mRNA, a stable RNA-protein complex is formed. This cyclolignan exhibits a wide array of biological properties ranges from piscicidal to antifungal, antiviral and antibacterial activities. In three-week (wk)-old NMRI mice four monoclonal antibody escape mutants caused an extensive infection of the olfactory epithelium and, like a wild type strain, a lethal brain infection after spread along olfactory pathways.

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The latter also represents a mechanism for the transport of homocysteine in plasma. They were tested in two tasks, one involving hierarchical global/local stimuli, the other involving face-like or geometrical stimuli where the processing of the inter-elemental spatial relationships was emphasized.

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Prediction of the bovine rhodopsin secondary structure and its sequence similarity with bacteriorhodopsin. Sarcopenia associated with renal function in the patients with type 2 diabetes. After the implementation of CNG since April 2001, Delhi has the highest fraction of CNG-run public vehicles in the world and most of them were introduced within 20 months.

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No patients had any problems in carrying or handling the data-logger and compliance was good. Three levels of diagnostic confidence are differentiated: Definite, Probable, and Possible. Cholesterol depletion disorganizes oocyte membrane rafts altering mouse fertilization. Comparison of the polarographic behavior of N-methyl-nicotinic acid chloride and nicotinic acid

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Editorial: Current Challenges and Future Perspectives on Emerging Bioelectrochemical Technologies. 20 children with nonepileptic psychogenic seizures and 30 children with tension type headaches, aged 11.3 - 17.11 years.

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In this way pellicular anion chromatography in combination with this postcolumn reaction reaction to be a sensitive and specific HPLC procedure for analysis of monosaccharides and oligosaccharides in complex biological matrices. Metabonomics study on the hepatoprotective effect of polysaccharides from different preparations of Angelica sinensis. Excited electronic potential-energy surfaces and transition moments for the H3 system.

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We demonstrate the moving tube technique on two small molecules (thymol and butylhydroxytoluene) and show good carbon-13 quantification. Hippocampal atrophy, epilepsy duration, and febrile seizures in patients with partial seizures. EFFECT OF PROGESTERONE ON THE OXYTOCIC ACTION OF ESTRADIOL-17-BETA. We conducted a Phase II study of biweekly oxaliplatin plus oral tegafur-uracil in the preoperative chemoradiotherapy (CRT) for locally advanced resectable mid-to-lower rectal cancer in our hospital, to evaluate the feasibility of this drug combination in tumor pathologic response, acute toxicity, local control, disease-free survival (DFS), overall survival (OS), and time to distant metastasis in an Asian cohort. In the anterior CNS, however, there is only a limited number of foci of RA synthesis, and less attention has been placed on regions such as the anterior hindbrain where RA synthesizing enzymes are absent.

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After HRP-injection into the VB, peroxidase-positive cells were observed contralaterally in the dorsal column nuclei (DCN), in the trigeminal nuclei and in the lateral cervical nucleus (LCN), and ipsilaterally in the somatosensoty I (SI) and II (SII) cortical areas. Its output (synaptic potential) sharply increases at emergence of the precisely certain interpulse interval in an input pulse sequence. An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma.

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We also performed the experiment with the biopsy needle for in vivo tumor detection in rabbits. Human germinal matrix: venous origin of hemorrhage and vascular characteristics. Effects of Xuebijing on hypothalamus-pituitary-adrenal axis in early stage of septic rats

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Changes in the activity of cortical neurons after administration of biogenic amines The use of a combination of different dental implants in a patient.

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The lack of standardized protocol, the inhomogeneity of groups and the absence of long-term studies preclude objective comparisons between the different beta-adrenoceptor antagonists. As expected, the radon concentrations were found to depend strongly on the ventilation in the three experimental halls.

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This minimal adhesiotomy method is technically simple, safe and time-saving. Three-way fluorescence data and multivariate calibration based on parallel factor analysis (PARAFAC) are combined for the simultaneous quantitation of three fluoroquinolone anitibiotics (norfloxacin, enoxacin, and ofloxacin) in human serum samples. Reorganisation of the daily working plans is one of the recommendations for improvement. Hospital discharge on the first compared with the second day after a planned cesarean delivery: a randomized controlled trial.

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The growth process of InAs quantum dots grown on GaAs (511)A substrates has been studied by atomic force microscopy. In vapour phase toxicity tests with female lice, benzaldehyde and salicylaldehyde were much more effective in closed containers than in open ones, indicating that the mode of delivery of these compounds was largely due to action in the vapour phase. Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction. The internally truncated LRP5 receptor presents a therapeutic target in breast cancer.

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Histomorphometric analysis of the intramedullary bone response to titanium particles in wild-type and IL-1R1 knock-out mice: a preliminary study. Screening siblings for inborn errors of fatty acid metabolism in families with a history of sudden infant death.

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In those patients taking sulphonylureas insulin secretion can be demonstrated to be higher, but there are also data which have been interpreted as evidence that these drugs may cause an alteration in peripheral insulin sensitivity. Here, we have used highly faceted cubic Pt seeds to direct the epitaxial overgrowth of a secondary metal. Labelled cells and immunoreactivity for the receptor and substance P were identified by using three different fluorophores and the relationships between them were assessed in single optical sections with three-colour confocal laser scanning microscopy.

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Post-traumatic facial paralysis without any fracture of the petrous bone Cocaine-evoked synaptic plasticity of excitatory transmission in the ventral tegmental area. The results indicate a deficiency in collagen type III in patients with varicose veins.

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With the help of a recently developed non-equilibrium approach, we investigate the ionic strength dependence of the Hubbard-Onsager dielectric decrement. Here, gel electrophoretic, mass spectroscopic, and chemical kinetics methods were used to provide evidence that medicinally relevant concentrations of 4 rapidly form covalent adducts with abasic sites in double- and single-stranded DNA under physiological conditions.

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Analysis showed that the Double-coding Test differentiates between clinical group and normal children more effectively than does the WISC-R Coding B subtest or the d2 Test. Treatment with everolimus reduces the size of SEGA associated with TSC with an adequate safety profile, and constitutes an alternative to surgery in certain cases. We observed also that specific T cells could be detected in a blood sample with a high sensitivity by using an A68/LAGE-1 fluorescent multimer.

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With the combination of TBX5 and MEF2C, GATA4 can reprogram postnatal fibroblasts into functional cardiomyocytes directly. Skin changes in advanced age--biochemical findings corresponding to morphology? In 2008, we initiated a prospective study to explore the frequency and predictive value of epidermal growth factor receptor (EGFR) mutations in an unselected population of Danish patients with non-small cell lung cancer offered treatment with erlotinib, mainly in second-line. This suggested that the unique structures of rice and barley stamen filaments should be fit for their function of elongation in anthesis, and also endow with the susceptibility to the fungus, V. Recently there has been an increase in the number of case reports detailing the recurrence of cancer in the pancreatic remnants following surgical resection of intraductal papillary mucinous carcinoma (IPMC) of the pancreas.

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Caudate nucleus hypointensity in the elderly is associated with markers of neurodegeneration on MRI. Healing kinetics of periapical lesions enhanced by the apexum procedure: a clinical trial. Subendocardial and intramural temperature response during radiofrequency catheter ablation in chronic myocardial infarction and normal myocardium. KERATINOLYTIC ACTIVITY OF MICROSPORUM CANIS AND MICROSPORUM GYPSEUM. Nutrient assimilation studies included determination of serum carotene levels, D-xylose absorption and fat absorption.

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Comparison of barbiturate blood levels measured in the hospital and the Medicolegal Institute, following acute poisonings with intermediate and short acting barbiturates. Recent research has shown that retinal oximetry could become an important clinical tool in glaucoma. Antigenic mimicry between microbes and cardiac proteins causes autoimmunity in myocarditis. A onefold reduction in the dimensionality of the original rotating-frame experiment is achieved by using a train of strong radiofrequency pulses separated by short acquisition windows.

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Renal insufficiency is a very important manifestation and affects the prognosis of patients. Hepatitis C virus infection: evidence for an association with type 2 diabetes.

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Recognition of psychiatric disorders, and self-perceived problems. With the introduction of technetium-99m mercaptoacetyltriglycine (99mTc-MAG3), a tracer with a high renal extraction, the estimation of DRF might hopefully become accurate and reproducible both between observers in the same institution and also between institutions. New aspects of the clinicopathology and genetic profile of metachronous multiple lung cancers. Tryptophan stimulation of growth and sporulation of Rhizopus arrhizus Fischer. Constitutively active STAT5A partially restores tube formation in the presence of Src or Jak2 inhibitors.

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These nationwide data suggest that better thyroid disease management is required, particularly during the first two trimesters of pregnancy, together with vigilant monitoring. Despite their low degree of sequence homology, yeast and plant FTases shared similar in vivo and in vitro substrate specificities, demonstrating that this enzymatic modification of proteins with intermediates from the isoprenoid biosynthesis pathway is conserved in evolutionarily divergent eukaryotes.

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At this level, they are observed exclusively in the dorsolateral space adjacent to the roof of the neural tube. Each relapse is accompanied by elevation of sIL-2R alpha and sICAM-1 in serum, during remission serum levels of both molecules do not changed significantly. Treatment of attention deficit disorders in adulthood using psychostimulants and low-dose neuroleptics--a critical case report Despite the success of tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 oncokinase, patients are not considered to be cured with the current therapy modalities.

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Diet has been reported to influence arterial blood pressure, and evidence indicates that the Mediterranean diet reduces cardiovascular mortality. Performance on Reversed Digit Repetition (RDR) was investigated using 102 subjects with documented disease of the central nervous system. The clinical significance of isolated hypoprolactinemia is discussed. Three of four recipients of transfusion in the United States are patients undergoing surgery, and despite promising advances in the development of alternatives to allogeneic blood transfusion, it is likely that for years to come this patient population will remain dependent on blood donated by volunteers.

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Heart rate variability (HRV) analysis was performed on recordings obtained before, during, and after a standard mental arithmetic task to induce mental stress. The location of the proteolytic cleavage site, which creates the N-terminus of mature HTLV-1 reverse transcriptase, has not been previously identified. Since then reports suggest that this higher dose of atropine may be of some limited value in treating this highly resistant form of arrest. Another assay has been developed in which the toxin A binds to the red cells and then the erythrocytes are agglutinated with antitoxin. ROS-mediated genotoxicity of asbestos-cement in mammalian lung cells in vitro.

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We have previously demonstrated that the facilitatory effect of the amygdala on the hypothalamo-pituitary-adrenocortical (HPA) axis responses to photic stimulation depends on the presence of norepinephrine (NE) in this region. The long cycle is a genuine alternative for these women to the improvement in living quality and hygiene even if for this purpose extensive great studies are not yet available. Fixed rabies virus strain M512 was shown to propagate in BHK cell cultures without interfering with cell growth.

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Effect of pinealectomy and melatonin on vasopressin-potentiated passive avoidance in rats. MediAgent: a WWW-based scalable and self-learning medical search engine. Hence, the need for new drugs and therapeutic strategies aiming at minimizing damage accrual through a better control of disease activity and a steroid-sparing potential is paramount.